Test 3 groups Flashcards
Cephalosporins
Group 1 Gen 1: Cephapirin, Cefazolin Group 2 Gen 1: Cephalexin Group 3 Gen 2: Cefoxitin Group 4 Gen 2:Cefotaxime, Ceftiofur, Cefovecin Group 5 Gen 3: Cefpodoxime Group 7 Gen 4: Cefepime
Antiviral
Amantadine
Inhibit fungi
▪amphotericin B, nystatin
▪caspofungin, flucytosine, terbinafine
▪fluconazole, griseofulvin, itraconazole, ketoconazole, posaconazole, voriconazole, miconazole
Binds ergosterol
▪amphotericin B, nystatin
Inhib Glucan
caspofungin
Antimetabolite antifungal
Flucytosine
Inhibit mitosis antifungal
Griseofluvin
Target Squalene epoxidase to inhibit ergosterol synth
Terbinafine
Inhibit ergosterol synth.
▪fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, miconazole
Common AE of ..azoles
Hepatopathy, Inhibit P450 Endocrine changes (except itraconazole)
Common AE of binding ergosterol (systemic admin)
▪amphotericin B, nystatin
AE: Nephrotoxicity, fever, phlebitis, tremors, renal K wasting
Urinary promoters
Bethanechol, Phenoxybenzamine
Reduce incontinence
Adrenergic agonist: Phenylpropanolamine
Estrogen: Estriol, Diethylstilbesterol
Reduce urinary calculi
Acidify urine: ammonium chloride.
Alakalize urine: potassium citrate
Diruretics
acetazolamide, furosemide, hydrochlorothiazide, spironolactone
mannitol
Fluid therapy
hetastarch, hypertonic (7.5%) saline
Normal saline, Ringer’s
lactated Ringer’s, Normosol-M, Normosol-R, Plasma-Lyte A, Plasma-Lyte M
Muscle paralysis
3 curs suck
Atracurium, Cisatracurium, Pancuronium
Succinylcholine
Inc muscle relaxation
▪diazepam, guaifenesin
Reverse muscular blockade
edrophonium, neostigmine, physostigmine
Inc muscle mass
▪estradiol, progesterone, testosterone, trenbolone
Inc heart rate and cardiac contractility
Epinephrine, Isoproterenol, Dopamine, Atropine, Glycopyrrolate. (Dobutamine)
Inc cardiac contractility with out inc of heart rate
Digoxin, Pimobendan, Dobutamine
Vasodilation
▪PIMOBENDAN, CARVEDILOL, HYDRALAZINE, AMLODIPINE, DILTIAZEM, benazepril, enalapril
Vasoconstriction
EPINEPHRINE, phenylephrine, dopamine, (dobutamine)
Dec sympathetic output
PROPRANOLOL, TIMOLOL, ATENOLOL
CARVEDILOL
BENZAPRIL, ENALAPRIL
Anticoagulants
Asprin, clopidogrel, dalteparin
Antiarrythmics
Quinidine, procainamide, lidocaine.
Sotalol, carvedilol.
Amiodarone.
Diltiazem.
Membrane stabalizers
Class 1.
Quinidine, Procainamide, Lidocaine
Beta blockers
Class 2.
Sotalol, Carvedilol
Block K channels to prolong action potential
Class 3.
Amiodarone
Ca channel blocker
Class 4.
Diltiazem
Dilate bronchioles
Albuterol, Clenbuterol
Dec coughing
Hydrocodone
Antineoplastics
5-FU, cisplatin, cyclophosphamide, cytarabine, doxorubicin, L-asparaginase, lomustine, methotrexate, piroxicam, toceranib , vincristine
Reduce seizures
Phenobarbital, phenytoin.
Diazepam.
Gabapentin, levetiracetam, potassium bromide, zonisamide
Anticonvulsants: barbituates
Phenobarbital, phenytoin
Anticonvulsants: succinimides
Diazepam
Drugs used for status epileptic
Diazepam,
Other benzodiazepines,
Phenobarbital,
Inhalant anesthetics.
Sedatives
Xylazine, Romifidine, Dexmedetomidine, Detomidine.
Acepromazine, Chlorpromazine.
Diazempam, Midazolam, Lorazopam.
Alpha 2:
Sedatives,
Reversals.
Alpha 2 agonists: Xylazine, Detomidine, Dexmedetomidine, Romifidine.
Alpha 2 antagonists: Yohimbine, Tolazoline, Atipamezole.
Phenythiazines
Acepromazine, Chlorpromazine.
Benzodiazepams:
Sedatives,
Reversals.
Sedatives: Diazepam, Midazolam, Lorazopam.
Reversals: Flumazenil.
Reversals
Yohimbine, Tolazoline, Atipamezole.
Flumazenil.
Naloxone, Naltrexone.
Opiate antagonists
Naloxone, Naltrexone.