test 3 giardia and trichomonas Flashcards

1
Q

What is an axostyle?

A

tube like organelle in some flagellates. extends from the area of the kinetosome to the posterior end.

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2
Q

What is a kinetosome?

A

basal bodies specifically found in ciliates.

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3
Q

Where does Trichomonas vaginalis? T. hominis? T. tenax? T. foetus?

A

T. vaginalis lives in the reproductive tract.
T. hominis lives in the gut.
T. tenax lives in the mouth.
T. foetus parasitizes cattle.

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4
Q

How long can Trichomonis live outside the body?

A

only 1-2 hours, or up to 24 if in urine.

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5
Q

What about a T. vaginalis infection causes vaginitis?

A

Desquamation and inflammation

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6
Q

Describe the life cycle of T. vaginalis.

A

Gets passed from person to person by sexual intercourse. In the reproductive tract the parasite multiplies by binary fission.

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7
Q

Where are the most common sites of a T. vaginalis infection?

A

Urethra in men.

Vagina in women.

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8
Q

What are the symptoms of T. vaginalis infection?

A

Women: Creamy, frothy discharge; itching, burning; dysuria.
Men: asymptomatic. ocasionally urethritis

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9
Q

How does T. vaginalis cause cell death?

A

secreted proteases at the site of parasite attachment.

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10
Q

What is the treatment for T. vaginalis?

A

oral metronidazole

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11
Q

What is the undulating membrane?

A

little wavy thing on the parasites body.

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12
Q

How many flagella does T. vaginalis have?

A

4

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13
Q

Why is a T. fetus such a big problem?

A

causes sponaneous abortions within the first trimester.

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14
Q

If a bull is infected with T. fetus what is the solution?

A

THey are usually culled because no approved therapy is available.

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15
Q

Where does T. tenax live in the mouth?

A

in the tartar around teeth or in teeth defects. associated with pus pockets.

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16
Q

Which of the 3 human trichomonas is the least common?

A

T. hominis. lives in the colon.

17
Q

Who was probably the first person to discover giardia?

A

Leeuwenhoek

18
Q

What is the most common flagellate of the human digestive tract? How many cases are there per year?

A
Giardia intestinalis (lamblia or duodenalis)
200 million
19
Q

Why is the zoonotic transmission of giardia controversial?

A

They havent been able to find a clear link between human and animal infections. Giardia could infect a wide range of hosts or each species could have its own type of giardia. Transmission between dogs and humans is rare.

20
Q

What is the best way to remove the parasite from water? How long can cysts survive in cold water?

A

Filtration. Chemicals like chlorine wont kill the parasite.

weeks to months.

21
Q

How much of the population in developing countries is infected with giardia? U.S.?

A

10%

4%

22
Q

How does giardia feed? What is the effect?

A
attaches to the microvilli.
causes malabsorption (lactase def. carbs, fats, B12 lost), flattening of the villi, duodenal ulcerations.
23
Q

How many cases are asymptomatic?

A

2/3 in endemic areas, 1/3 in an outbreak.

24
Q

how long is the incubation period?

A

1-3 weeks.

25
Q

how long does it take for the symptoms to resolve?

A

1-4 weeks

26
Q

How does one diagnose a G. lamblia infection?

A

cysts or trophozoites in the stool. antigen detection. UGI biopsies or aspirates

27
Q

What drug is used to treat giardia infection?

A

metronidazole.

28
Q

What is the best way to remove pathogens from a water supply?

A

filter.