Test 3: Chapters 6b, 8, 9 Flashcards
Functions of bone remodeling
Resorption and deposition of bone to:
- adjust bone shape (maintains thickness of compact bone)
- regulate blood calcium & phosphate
- assist repair of broken bones
Normal blood calcium level?
9.2-10.4 mg/dL
Normal blood phosphate level
3.5-4.0mg/dL
What are the effects of hypocalcemia (insufficient blood calcium)
Over excitability of the nervous system; muscle tremors & tetany-carpopedal spasm (ankle/wrist), laryngospasm (throat)
Effects of hypercalcemia (excessive blood calcium)
Depresses nervous system-sluggish reflexes; muscle weakness-cardiac arrest
Calcitrol- where it comes from and how it maintains calcium homeostasis
Form of vitamin D from kidney-raises blood calcium; increases Ca absorption in intestine, stimulates osteoclasts to remove Ca from bone, promotes Ca reabsorption by kidneys
Parathyroid hormone (PTH)
Raises blood Ca; stimulates osteoclasts, inhibits osteoblasts so less Ca is added to bone, promotes Ca reabsorption by kidneys
Calcitonin- where it comes from and how it maintains homeostasis
From thyroid C cells; lowers blood Ca; inhibits osteoclasts so less Ca is removed from bone, stimulates osteoblasts so more Ca is added to bone
What are the steps bone repair
- Hematoma forms
- Fibrocartilaginous callus formation
- Bony callus formation
- Bone remodeling
What causes achondroplastic dwarfism
Growth hormone(GH) deficiency limits long bone growth
What causes Rickets and osteomalacia
Rickets-In kids
Osteomalacia-in adults
Vitamin D or Ca deficiency softens bone
What causes osteoporosis
Bone loss from deficient estrogen/activity
What causes osteomyelitis
Bacterial infection of bone marrow
What is osteoma
Benign tumors in skull bone
What is osteochondroma
Benign bone/cartilage tumor of long bone
What is osteosarcoma
Malignant cancer in long bones
What is chondrosarcoma
Cancer in hyaline cartilage
3 functional classes of joints & examples of each
- synarthroses: little or no movement Ex)skull bones, periodontal ligaments, tibia-fibula, radius-ulna, sternum-rib 1, epiphysis-diaphysis
- amphiarthroses: slightly moveable Ex)intervertebral disc, pubic symphysis
- diarthroses: freely moveable Ex) most appendicular joints
3 structural classes and examples of each
- fibrous: collagen fibers Ex) skull bones, periodontal ligaments, tibia-fibula, radius-ulna
- cartilagenous: cartilage Ex) sternum-rib 1, epiphysis-diaphysis, intervertebral disc, pubic symphysis
- synovial: synovial fluid in synovial cavity Ex) most appendicular joints
Two types of cartilagenous joints and examples
- synchodroses-hyaline cartilage Ex) sternum-rib 1, epiphysis-diaphysis
- sympheses-fibrocartilage Ex) intervertebral disc, pubic symphysis
What is synostoses & give examples
Fibrous or cartilagenous joints that ossify after growth Ex) skull bone joints (sutures), epiphysis to diaphysis, 1st rib to sternum
Features present in all synovial joints
- Articular cartilage
- Joint cavity
- Synovial fluid
- Articular capsule
- Ligaments & tendons
- Nerve & blood vessels
Features of synovial joints only in some joints
- Meniscus (cartilage pads)
- Bursa (fibrous sac with synovial fluid)
- Tendon sheath (cylindrical bursa)
What are all the types and categories of synovial joints
A.) nonaxial- slipping or gliding movement
1. Plane: wrist-carpals, ankle-tarsals
B.) Uniaxial-movement in one plane
2. Hinge: elbow-humerus & ulna, knee-femur & tibia
3. Pivot: elbow-radius & ulna
C.) biaxial-movement in 2 planes
4. Condyloid: base of fingers
5. Saddle: base of thumb
D.) multiaxial- movement in 3 planes
6. Ball & socket: shoulder and hip
Flexion
Decreases joint angle
Extension
Increases (straightens) joint angle
Hyperextension
Joint extension greater than 180 degrees
Abduction
Moving body part away from midsagittal line
Adduction
Moving body part toward midsagittal line
Circumduction
Circular movement of distal end of appendages
Rotation
Bone turns on long axis; medial and lateral
Supination
Palm faces forward or upward
Pronation
Palm faces backward or downward