Test #2 Autoimmune ARTICLES- Dwayne Flashcards

1
Q

The majority of carcinoid tumors are located where/

A
GI tract (appendix, rectum, and ileum)
Bronchial tree
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2
Q

carcinoid tumors

A

Slow growing, small bowel tumors

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3
Q

Which tumor bypass the liver

A

Bone, hepatic, gonadal, pulmonary

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4
Q

S/S of carcinoid tumors

A

hypotension, HTN, Flushing (most reported), broncho-constriction, diarrhea

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5
Q

carcinoid tumors produce excess of what?

A

Serotonin (the most) histamine and kinins

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6
Q

Serotonin can cause HTN and Hypotension why?

A

Indirect stimulation of Norepi release

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7
Q

Serotonin is metabolized by?

A

MOA and aldehyde dehydrogenase

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8
Q

Most common test to diagnose carcinoid tumors is

A

5-HIAA 24 hr urine assay

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9
Q

Treatment for carcinoid tumors is

A

octreotide and surgical removal

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10
Q

Octreotide

A

synthetic somatostatin with a long 1/2 life

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11
Q

What NMB is recommended for these Pts

A

Vec r/t cardiovascular stability

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12
Q

Most common complication during surgery?

A

cardiovascular instability

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13
Q

carcinoid tumors cardiovascular effects what side of the heart

A

Right side

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14
Q

Avoid what drugs R/T histamine release in these pts?

A

morphine and actracurium

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15
Q

SLE is what? systemic Lupus Erythemiatosus

A

chronic inflammatory disease of unknown cause that effects jpints, kidneys, lungs, nervous system and serous membranes

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16
Q

2 antibodies common for SLE

A

anti-double-stranded DNA antibodies and anti-Sm antibodies

17
Q

what test is the best diagnostic test for SLE

A

(ANA) antinuclear antibody test

18
Q

Weight gain in SLE is due to

A

Hypoalbuminemia, water and salt retention

19
Q

earliest S/S of Lupus is?

A

joint pain in 90% of Pt’s

20
Q

Most common lesion in Lupus is?

A

Butterfly rash over face

21
Q

RA Assessment

A

Neck and airway assessment crucial, for subluxation of the atlanto-axial joint 25%

22
Q

RA S/S

A

joint pain w nodules, worse in the morning but improving with activity, fatigue, wt loss, depression and disability 25% of RA Pts

23
Q

atlanto-axial subluxation

A

80% anterior, 5% posterior, Vertical 10-20%

24
Q

Airway envolvement

A

Cricoarytnoid joints, w nodules may distort anatomy, ROM of Neck and TMJ mobility may interfere w mouth opening

25
Q

All RA Pts should have what test

A

C Spine xray

26
Q

Most common symptom of atlanto-axial subluxation is

A

pain radiating to the occiput the paraesthesia to the shoulders and arms with head movement

27
Q

Thyroidectomy are at high risk for what post-op?

A

PONV