Test 2 Flashcards
Is the pancreas composed mostly of endocrine or exocrine tissue?
both but mainly exocrine
what does the exocrine tissue help in?
Digestion-it secretes pancreatic juice and breaks up fat, carbohydrates, and protein into smaller molecules
What does the endocrine tissue help in?
- Hormones such as glucagon and insulin
- maintains sugar and salt balance
what type of cells does exocrine make?
Acini
What are the pancreatic juices composed of?
- amylase
- lipase
- trypsin
- chymotrypsin
- carboxypepidase
- nucleases
- sodium bicarbonate
how much does acini cells function in the exocrine tissue?
80%
what does lipase digest?
Fats
What does Amylase digest?
carbohydrates
What does trypsin, chymotrypsinogen, and carboxypeptidase digest?
Proteins
What does nucleases digest?
Nucleic acids
What does sodium bicarbonate digest?
Neutralize hydrochloric acid
what is hormone release stimulated by?
partially digested food
Hormones cause the production of________
pancreatic juices
what are the 2 ducts of the pancreas?
Duct of Wirsung (Main panc duct)
Duct of Santorini
What happens in the duct of Wirsung?
Pancreatic juice collects then moves into the duodenum through the ampulla of Vater
What does the sphincter of Oddi do?
relaxes to allow the passage of juices
what type of cells does the Langerhans consist of?
alpha, beta, and delta cells
Where do hormones secrete?
Into the blood stream
what is the action of Insulin?
Glucose to glycogen
What is the action of Glucagon?
Glycogen to glucose
What is the action of Somatostatin?
Alpha and Beta inhibitor (inhibit insulin and glucagon production)
Where does the pancreaticduodenal artery supply?
Supplies the head and part of the duodenum
Where does the branches of the splenic artery supply?
Supplies body and tail and later enters the spleen
Which vessel is tortuous?
splenic artery
Where does the pancreas lay?
in the retroperitoneum in the epigastric region
What is the uncinate considered a part of?
the neck
the head is more _____ to the body and tail
inferior
the neck and body is more _________ than head and tail
superficial
the tail is more _______ direction towards the spleen
superior
what is the echogenicity of the pancreas?
isoechoic or hyperechoic to the liver
True or false. Pancreas never changes with age?
False, the pancreas increases in echogenicity with age.
how does the uncinate appear to the rest of the pancreas?
hypoechoic
what is the echotexture of the pancreas?
homogenous
true or false, the size of the pancreas is comparable between sexes?
true
true or false, the pancreas increases in size with age?
false, the pancreas decreases in size with age
what is the largest and smallest part of the pancreas?
largest-head
smallest-neck (and the body and tail)
what is the contour of the pancreas?
usually smooth, sometimes lobulated
what are the landmarks that will help you visualize the pancreas?
Gastroduodenal Artery (GDA)
Common Bile Duct (CBD)
IVC
Where does the GDA lie?
Anterior lateral aspect of the pancreas head
Where does the CBD lie?
posterior lateral aspect of the head
what are the landmarks for the neck and uncinate process?
anterior to the SMV and portosplenic confluence
what are the landmarks for the pancreas body?
SMA
Splenic vein
SMV
Body is medial anterior to Portosplenic confluence
What are the landmarks for the pancreas tail?
Splenic vein lies posterior to the tail
Splenic artery is tortuous and travels adjacent to the splenic vein ( seen in cross section)
what does the Duct of Wirsung merge with?
merges with CBD before entering the duodenum at the major papilla or ampula of Vater
What ducts can be seen on ultrasound?
Duct of Wirsung (main pancreatic duct)
Duct of Santorini (accessory duct)
what is the size of the main pancreatic duct?
3mm or less
what are the windows used when scanning the pancreas?
- Supine
- Right anterior oblique and left lateral decubitus
- left coronal
what are some helpful imaging techniques for pancreas?
- try different window
- push belly out
- breath in
what are the 2 buds that formed the pancreas?
dorsal(cranial)
Ventral (caudal)
How did the two pancreatic ducts form?
arise from opposite sides foregut and midgut
When do the two pancreatic ducts form?
6 to 8 weeks
what part of the pancreas forms in each bud?
Dorsal-body and tail of pancreas
Ventral- Head and uncinate process
What is the annular pancreas?
A ring of pancreatic tissue that encircles the duodenum
what is agenesis?
absence of the body and tail (head is usually larger)
What is the pancreatic divisum?
most common
Lack of fusion of the dorsal and ventral pancreatic buds
What can normally happen with the pancreas head?
pseudomasses (false masses) not real but can fool you when scanning