Terminologies II (lec) Flashcards
Found on the surface of RBC
Antigen
Found in serum
Antibody
Antigen-antibody interaction;
Involves immune response of transfusion elements
Immunohematology
Blood Banking embraces the following:
- collection
- preparation
- processing
- preservation
- distribution of blood, blood components and derivatives
To separate or remove different components
Apheresis
Blood components
- Packed RBC
- WBC
- Plasma
- Platelet
Plasma that is -18 oC
Fresh Frozen Plasma
Two factors of leukocyte
Factor VIII
Factor IX
Composed of several antigens related to each other whose incidence vary to each other
Blood Group System
Genetically encoded antigen of the erythrocytes, leukocytes, platelet and plasma
Blood Group Antigen
Implies selection with preparation and infusion of blood, blood components and blood derivatives for each individual
Hemotherapy
An alternative gene of which may occupy a locus
Allelomorphs/Allele/Allelic
Alleles on ABO gene locus
A gene
B gene
O gene
Opposite allele; referring to antigens produced by allelic genes
Antithetical
Rh Blood Group System
D, C, c, E, e
Considered amorph silent gene; doesn’t produce detectable antigen
D
Having two or more alleles at a given locus
Polymorphic
Position occupied by a gene
Locus
Highly polymorphic than the ABO system
Rh blood group system
Genetic constitution which produces the trait; actual genetic make up from each parent; determined by family studies; individuals are categorized as homozygous or heterozygous
Genotype
Observable expression of inherited traits; commercially prepared reagents are used
Phenotype
Two loci of the chromosome are occupied by the same gene; antigenic control in double dose
Homozygous
Two loci of the chromosome is occupied by different genes; antigenic control in single dose
Heterozygous
Equal expression of two different inherited alleles
Codominant
Immune serum
Antiserum
Has water soluble A, B, H substances in their secretion (Se gene)
(Sese, SeSe)
Secretor
No water soluble A, B, H substances
sese
Non secretor
