Blood Component Preparation And Therapy Flashcards
5 min hard spin (5000 g)
PRBC
platelet con
7 min hard spin (5000 g)
Cryoppt
LP-PRBC
cell free plasma
3 min light spin (2000 g)
PRP
Centrifuge platelet con at RT. other blood components at _____
1-6 C
Used to replace RBC mass and plasma volume
Whole blood
Treatment of asymptomstic anemia where oxygen carrying capacity is needed
PRBC
For treatment of anemia
For neonates
RBC aliquots
Volume of leukocyte reduced rbc to prevent non-hemolytic febrile transfusion reaction
5x10^8
Volume of leukocyte reduced rbc to prevent HLA sensitization
5x10^6
Methods used to prepare leukocyte reduced rbc
Centrifugation
Filtration
First generation filter
- removes fibrin clots
170-260 um
Screen filter
Second generation filter
20-40 um
Micropore screen filter
Third generation filter
Adhesion filter
Blood component for treatment of AIHA PNH igA deficiency Allergic reaction
Washed rbc
For rare blood donor units
Frozen deglycerolized rbc
Used to treat multiple coagulation deficiencies
FFP
For replacement of fibrinogen
Source of factor VIII, XIII, VWF
Cryoppt
Replaced cryoppt for treatment of factor VIII and vwf deficiency
Factor viii concentrate
DDAVP
Storage of cryoppt
1 year at -18C
6 hrs if thawed at 20-24C
4 hrs if pooled
For patients with thrombocytopenia
Platelet con
For patients with neutropenia
Granulocyte/leukocyte concentrate
Treatment of stable coagulation deficiency especially factor IX
Plasma
For patients with hemophilia A or factor VIII deficiency
Factor VIII concentrate
For patients with hemophilia B or factor IX deficiency
Factor IX concentrate
Used for treatment of bleeding disorders other than hemophilia
Hypofibrinogenemia
Hypovolemia
Cryosupernate
For patients susceptible to TA GVHD
Gamma irradiated rbc
Gamma irradiated rbc
Cesium 137
Cobalt 60
Kinds of spin
Hard
Soft