teratogens Flashcards
1
Q
ACEi
A
renal tubular dysplasia renal failure oligo IUGR lack of cranial ossification
2
Q
alcohol
A
growth restriction pre and post birth
mental retardation
midfacial hypoplasia
renal and cardiac defects
3
Q
androgens
A
female virilization
male advanced genital development
4
Q
carbamzepine
A
NTDs fingernail hypoplasia microcephaly IUGR developmental delay
5
Q
cocaine
A
bowel atresias congenital malformations of heart, limbs, face, GU microcephaly IUGR cerebral infarctions
6
Q
DES
A
clearcell adenocarcinoma
vaginal adenosis
cervix, uterus, testes abnormalities
7
Q
lead
A
SAB
stillbirths
8
Q
lithium
A
Ebstein’s
9
Q
methotrexate
A
SAB
10
Q
mercury
A
cerebral atrophy microcephaly mental retardation spasticity seizures blindness
11
Q
phenytoin
A
IUGR
dysmorphic craniofacial
cardiac defects
fingernail hypoplasia
12
Q
radiation
A
microcephaly
mental retardation
13
Q
streptomycin and kanamycin
A
hearing loss, CN VIII damage
14
Q
tetracycline
A
teeth discoloration
hypoplasia of tooth enamel
15
Q
thalidomide
A
limb deformities
cardiac and GI anomalies
16
Q
trimethadione, paramethadione
A
cleft lip and cleft palate
cardiac defects
17
Q
VPA
A
NTD
craniofacial defects
18
Q
vitamin A
A
SAB small ears thymic agenesis CV defects microphthalmia cleft lip, cleft palate mental retardation
19
Q
warfarin
A
nasal hypoplasia stippled bone epiphyses developmental delay IUGR ophthalmologic anomalies
