teratogens Flashcards

1
Q

ACEi

A
renal tubular dysplasia
renal failure
oligo
IUGR
lack of cranial ossification
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

alcohol

A

growth restriction pre and post birth
mental retardation
midfacial hypoplasia
renal and cardiac defects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

androgens

A

female virilization

male advanced genital development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

carbamzepine

A
NTDs
fingernail hypoplasia
microcephaly
IUGR
developmental delay
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cocaine

A
bowel atresias
congenital malformations of heart, limbs, face, GU
microcephaly
IUGR
cerebral infarctions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

DES

A

clearcell adenocarcinoma
vaginal adenosis
cervix, uterus, testes abnormalities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

lead

A

SAB

stillbirths

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

lithium

A

Ebstein’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

methotrexate

A

SAB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

mercury

A
cerebral atrophy
microcephaly
mental retardation
spasticity
seizures
blindness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

phenytoin

A

IUGR
dysmorphic craniofacial
cardiac defects
fingernail hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

radiation

A

microcephaly

mental retardation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

streptomycin and kanamycin

A

hearing loss, CN VIII damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

tetracycline

A

teeth discoloration

hypoplasia of tooth enamel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

thalidomide

A

limb deformities

cardiac and GI anomalies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

trimethadione, paramethadione

A

cleft lip and cleft palate

cardiac defects

17
Q

VPA

A

NTD

craniofacial defects

18
Q

vitamin A

A
SAB
small ears
thymic agenesis
CV defects
microphthalmia
cleft lip, cleft palate
mental retardation
19
Q

warfarin

A
nasal hypoplasia
stippled bone epiphyses
developmental delay
IUGR
ophthalmologic anomalies