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step 2 > drug side effects > Flashcards

drug side effects Flashcards

1
Q

ACEis

A

COUGH

rash proteinuria angioedema teratogen

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2
Q

amantadine

A

ataxia

livedo reticularis

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3
Q

aminoglycosides

A

ototoxic

nephrotoxic (ATN)

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4
Q

amio

A 
AV block, hypoT, bradycardia
PULMONARY FIBROSIS
blue discoloration
corneal deposition
transaminases, hepatitis
thyroid shiz
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5
Q

ampho

A

nephrotoxic, bone marrow suppression, anemia

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6
Q

antipsychotics

A

sedation, movement crap, NMS

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7
Q

azoles

A

P450 inhibition

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8
Q

bile acid resins

A

GI upset

malabsorption

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9
Q

carbamazepine

A

P450 induction
agranulocytosis, aplastic anemia
liver toxicity

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10
Q

CCBs

A

PERiPHERAL EDEMA
constipation
cardiac depression

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11
Q

chloramphenicol

A

gray baby

aplastic anemia

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12
Q

cisplatin

A

nephrotoxicity

acoustic nerve damage

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13
Q

clonidine

A

severe rebound headache and hypertension

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14
Q

colzapine

A

agranulocytosis

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15
Q

cyclophosphamide

A

HEMORRHAGIC CYSTITIS

myelosuppression

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16
Q

digoxin

A

YELLOW VISUAL CHANGES
arrythmias
GI

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17
Q

doxorubicin

A

cardiomyopathy

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18
Q

fluoroquinolones

A

kids cartilage

adults Achilles

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19
Q

lasix

A

ototoxicity
hypokalemia
nephritis
gout

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20
Q

gemfibrozil

A 
myositis
LFT increase (reversible)
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21
Q

HCTZ

A 
hypoK
hypoNa
hyperU
hypergly
hyperCa
22
Q

statins

A 
myositis
LFT increase (reversible)
23
Q

hydral

A

drug induced lupus

24
Q

hydroxychloroquine

A

retinopathy

25
Q

INH

A

peripheral neuropathy (prevent with B6)
hepatotoxicity
g6pd hemolysis

26
Q

methanol

A

blindness

27
Q

methotrexate

A

hepatic fibrosis, pneumonitis, ANEMIA

28
Q

methyldopa

A

+ Coombs

drug lupus

29
Q

metronidazole

A

disulfiram reaction
metallic taste
vestibular dysfunction

30
Q

niacin

A

flushing

31
Q

nitroglycerin

A

hypoT, tachy, headache, tolerance

32
Q

penicillamine

A

drug lupus

33
Q

phenytoin

A

teratogen
gingival hyperplasia
hirsutism
nystagmus, diplopia, ataxia, arrhythmia

34
Q

prazosin

A

first dose hypotension

35
Q

procainamide

A

drug lupus

36
Q

propylthiouracil

A

agranulocytosis

aplastic anemia

37
Q

quinidine

A

cinchonism, thrombocytopenia, arrythmias

38
Q

reserpine

A

depression

39
Q

rifampin

A

I’M ALL ORANGE

P450 induction

40
Q

salicylates

A

respiratory alkalosis and metabolic acidosis
fever
dehydration, diaphoresis, hemorrhagic gastritis

41
Q

succinylcholine

A

malignant hyperthermia

hyperkalemia

42
Q

TCAs

A

QRS prolongation
sedation
coma
anticholinergic

43
Q

tetracyclines

A

tooth discoloration
photosensitivity
Fanconi’s syndrome
GI distress

44
Q

trimethoprim

A

megaloblastic anemia, leukopenia, granulocytopenia

45
Q

depakote

A

neural tube defects

hepatotoxicity

46
Q

vanc

A

RED MAN

nephro and oto

47
Q

vinblastine

A

severe myelosuppression

48
Q

vincristine

A

peripheral neuropathy

paralytic ileus

49
Q

methimazole

A

agranulocytosis
teratogen (1st tri)
cholestasis

50
Q

PTU

A

agranulocytosis
hepatic failure
vasculitis

step 2 (8 decks)

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