drug side effects Flashcards
ACEis
COUGH
rash proteinuria angioedema teratogen
amantadine
ataxia
livedo reticularis
aminoglycosides
ototoxic
nephrotoxic (ATN)
amio
AV block, hypoT, bradycardia PULMONARY FIBROSIS blue discoloration corneal deposition transaminases, hepatitis thyroid shiz
ampho
nephrotoxic, bone marrow suppression, anemia
antipsychotics
sedation, movement crap, NMS
azoles
P450 inhibition
bile acid resins
GI upset
malabsorption
carbamazepine
P450 induction
agranulocytosis, aplastic anemia
liver toxicity
CCBs
PERiPHERAL EDEMA
constipation
cardiac depression
chloramphenicol
gray baby
aplastic anemia
cisplatin
nephrotoxicity
acoustic nerve damage
clonidine
severe rebound headache and hypertension
colzapine
agranulocytosis
cyclophosphamide
HEMORRHAGIC CYSTITIS
myelosuppression
digoxin
YELLOW VISUAL CHANGES
arrythmias
GI
doxorubicin
cardiomyopathy
fluoroquinolones
kids cartilage
adults Achilles
lasix
ototoxicity
hypokalemia
nephritis
gout
gemfibrozil
myositis LFT increase (reversible)
HCTZ
hypoK hypoNa hyperU hypergly hyperCa
statins
myositis LFT increase (reversible)
hydral
drug induced lupus
hydroxychloroquine
retinopathy
INH
peripheral neuropathy (prevent with B6)
hepatotoxicity
g6pd hemolysis
methanol
blindness
methotrexate
hepatic fibrosis, pneumonitis, ANEMIA
methyldopa
+ Coombs
drug lupus
metronidazole
disulfiram reaction
metallic taste
vestibular dysfunction
niacin
flushing
nitroglycerin
hypoT, tachy, headache, tolerance
penicillamine
drug lupus
phenytoin
teratogen
gingival hyperplasia
hirsutism
nystagmus, diplopia, ataxia, arrhythmia
prazosin
first dose hypotension
procainamide
drug lupus
propylthiouracil
agranulocytosis
aplastic anemia
quinidine
cinchonism, thrombocytopenia, arrythmias
reserpine
depression
rifampin
I’M ALL ORANGE
P450 induction
salicylates
respiratory alkalosis and metabolic acidosis
fever
dehydration, diaphoresis, hemorrhagic gastritis
succinylcholine
malignant hyperthermia
hyperkalemia
TCAs
QRS prolongation
sedation
coma
anticholinergic
tetracyclines
tooth discoloration
photosensitivity
Fanconi’s syndrome
GI distress
trimethoprim
megaloblastic anemia, leukopenia, granulocytopenia
depakote
neural tube defects
hepatotoxicity
vanc
RED MAN
nephro and oto
vinblastine
severe myelosuppression
vincristine
peripheral neuropathy
paralytic ileus
methimazole
agranulocytosis
teratogen (1st tri)
cholestasis
PTU
agranulocytosis
hepatic failure
vasculitis