Teratogens Flashcards
1
Q
ACE inhibitors
A
Renal damage
2
Q
Alkylating agents
A
Absence of digits
3
Q
Aminoglycosides
A
CN VIII toxicity
4
Q
Carbamazepine
A
Neural tube defects Craniofacial defects Fingernail hypoplasia Developmental delay IUGR
5
Q
DES
A
Vaginal clear cell adenocarcinoma
Congenital mullerian anomalies
6
Q
Folate antagonists
A
Neural tube defects
7
Q
Lithium
A
Ebstein anomaly
8
Q
Methimazole
A
Aplasia cutis congenita
9
Q
Phenytoin
A
Fetal hydantoin syndrome
10
Q
What is Fetal hydantoin syndrome
A
Microcephaly Dysmorphic craniofacial features Hyplastic nails and distal phalanges Cardiac defects IUGR Intellectual disability
11
Q
Tetracyclines
A
Discoloured teeth
12
Q
Thalidomide
A
Limb defects
13
Q
Valproate
A
Inhibition of maternal folate absorption
14
Q
Warfarin
A
Bone deformities
15
Q
Alcohol
A
FAS
16
Q
Cocaine
A
Placental abruption
17
Q
Smoking
A
LBW Preterm labor Placental problems IUGR ADHD
18
Q
Iodine
A
Goiter
Hypothyroidism
19
Q
Maternal diabetes
A
Caudal regression syndrome
Congenital heart defects
Neural tube defects
20
Q
Vitamin A excess
A
Spontaneous abortions
Birth defects
21
Q
X-rays
A
Microencephaly
Intellectual disability
