Plasmid-mediated mechanisms of drug resistance Flashcards

1
Q

Production of beta lactamases and cleavage of beta lactam rings

A

Penicillins

Cephalosporins

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2
Q

Inactivation by acetylation, adenosylation, phosphorylation

A

Aminoglycosides

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3
Q

Inactivation by acetylation only

A

Chloramphenicol

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4
Q

Increased efflux

A

Tetracyclines

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5
Q

Active export and lowered affinity

A

Sulfonamides

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6
Q

Ligase produces cell wall pentapeptidases terminating in D-ala-D-lactate

A

Vanco

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