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First Aid 2014 Flashcards > Exotoxin mechanisms > Flashcards

Exotoxin mechanisms Flashcards

1
Q

Inactivate EF-2

A

Diptheria

P. aeruginosa

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2
Q

Inactivate 60S by removing adenine and can cause HUS

A

Shiga

EHEC

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3
Q

Increase cAMP and cGMP (overactivation)

A

ETEC heat stable

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4
Q

Mimic adenylate cyclase (increase cAMP)

A

B. anthracis

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5
Q

Overactivate adenylate cyclase (increase cAMP)

Permanent activation of Gs

A

V. cholerae heat labile

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6
Q

Overactivate adenylate cyclase (increase cAMP)

Disabling Gi

A

Pertussis

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7
Q

Cleave SNARE

A

Tetanus

Botulinum

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8
Q

Lecithinase

A

C. perfringes

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9
Q

Streptolysin O degrades cell membranes

A

S. pyogenes

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10
Q

Bind MHC II and TCR leading to excessive IFN-gamma and IL-2

A

S. aureus

S. pyogenes

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First Aid 2014 Flashcards (113 decks)

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