Drug reactions Flashcards

1
Q

Coronary vasospasm

A

Cocaine
Sumatriptan
Ergot alkaloids

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2
Q

Cutanous flushing

A

Vanco
Adenosine
Niacin
CCBs

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3
Q

Dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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4
Q

Torsades de pointes

A
Class III, IA
Macrolides
Antipsychotics
TCAs
Chloroquine
Protease inhibitors
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5
Q

Adrenocortical insufficiency

A

Glucocorticoid withdrawal

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6
Q

Hot flashes

A

Tamoxifen

Clomiphene

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7
Q

Hyperglycemia

A
Tacrolimus
Protease inhibitors
Niacin
HCTZ
Beta-blockers
Corticosteroids
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8
Q

Hypothyroidism

A

Lithium
Amiodarone
Sulfonamides

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9
Q

Acute cholestatic hep

Jaundice

A

Erythromycin

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10
Q

Diarrhea

A
Metformin
Erythromycin
Colchicine
Orlistat
Acarbose
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11
Q

Focal to Massive hepatic cirrhosis

A

Halothane
Amanita phalloides
Valproate
Acetaminophen

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12
Q

Hepatitis

A

INH

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13
Q

Pancreatitis

A
Didanosine
Corticosteroids
Alcohol
Valproate
Azathioprine
Diuretics
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14
Q

Pseudomembraneous colitis

A

Clindamycin
Ampicillin
Cephalosporins

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15
Q

Agranulocytosis

A
Dapsone
Clozapine
Carbamazepine
Colchicine
Methimazole
PTU
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16
Q

Aplastic anemia

A
Carbamazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
PTU
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17
Q

Direct Coombs

A

Methyldopa

Penicillin

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18
Q

Gray baby

A

Chloramphenicol

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19
Q

G6PD hemolysis

A
INH
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
20
Q

Megaloblastic anemia

A

Phenytoin
MTX
Sulfa drugs

21
Q

Thrombocytopenia

A

Heparin

Cimetidine

22
Q

Thrombotic complications

23
Q

Fat redistribution

A

Protease inhibitors

Glucocorticoids

24
Q

Gingival hyperplasia

A

Phenytoin
Verapamil
Cyclosporine
Nifedipine

25
Hyperuricemia and gout
``` Pyrazinamide Thiazides Furosemide Niacin Cyclosporine ```
26
Myopathy
``` Fibrates Niacin Colchicine Hydroxychloroquine IFN-alpha Penicillamine Statins Glucocorticoids ```
27
Osteoporosis
Corticosteroids | Heparin
28
Photosensitivity
Sulfonamides Amiodatone Tetracyclines 5-FU
29
Rash - Stevens-Johnson
``` Ethosuximide Carbamazepine Lamotrigine Phenytoin Phenobarbitol Allopurinol Sulfa drugs Penicillin ```
30
SLE
``` Sulfa drugs Hydralazine INH Procainamide Phenytoin Etanercept ```
31
Teeth discoloration
Tetracyclines
32
Tendonitis, Tendon rupture, Cartilage damage
Fluoroquinolones
33
Cinchonism
Quinidine | Quinine
34
Parkinson-like
Antipsychotics Reserpine Metoclopromide
35
Seizures
``` INH Buproprion Imipenem/Cilastatin Tramadol Enflurane Metoclopromide ```
36
Tardive diskinesia
Antipsychotics | Metoclopromide
37
DI
Lithium | Demeclocycline
38
Fanconi
Expired tetracycline
39
Hemorrhagic cycstitis
Cyclophosphamide | Ifosfamide
40
Interstitial nephritis
Methicilin NSAIDs Furosemide
41
SIADH
Carbamazepine Cyclophosphamide SSRIs
42
Dry Cough
ACE inhibitors
43
Pulmonary Fibrosis
Bleomycin Busulfan Amiodarone MTX
44
Antimuscarinic
Atropine TCAs H1 blockers Antipsychotics
45
Disulfiram
``` Metro Some Cephalosporins Griseofulvin Procarbazine 1st gen sulfonamides ```
46
Nephro/Ototoxicity
Aminoglycosides Vanco Loops Cisplatin