Oncogenes Flashcards
1
Q
BCR-ABL
A
CML
AML
Tyrosine kinase
2
Q
Bcl-2
A
Follicular and undifferentiated lymphoma
Anti-apoptotic
3
Q
BRAF
A
Melanoma
Ser/Thr kinase
4
Q
c-kit
A
GIST
Cytokine receptor
5
Q
c-myc
A
Burkitt lymphoma
Transcription factor
6
Q
Her2/neu
A
Breast
Ovarian
Gastric carcinoma
Tyrosine kinase
7
Q
L-myc
A
Lung tumor
Transcription factor
8
Q
N-myc
A
Neuroblastoma
Transcription factor
9
Q
Ras
A
Colon cancer
Lung cancer
Pancreatic cancer
GTPase
10
Q
Ret
A
MEN 2A, 2B
Papillary thyroid carcinoma
Tyrosine kinase