TCA cycle Flashcards
1
Q
The first reaction in the TCA cycle is _____ with ____ converted to ____ via ______
A
Oxaloacetate, Acetyl-CoA, Citrate Synthase
2
Q
What drives the first reaction of TCA cycle forward?
A
Hydrolysis of Acetyl-CoA Thioester
3
Q
The second enzyme of the TCA cycle is ___
A
Aconitase
4
Q
What is the second step in TCA Cycle?
A
Conversion of Citrate to Isocitrate via aconitase
5
Q
What is the third step in the TCA cycle?
A
Conversion of Isocitrate to alpha-ketoglutarate via isocitrate dehydrogenase, generates NADH
6
Q
What reaction proceeds similarly to pyruvate dehydrogenase and why?
A
The decarboxylation of alpha-ketoglutarate into Succinyl-CoA
7
Q
______ reactions deplete the components of the cycle
A
Cataplerotic
8
Q
_____ reactions replenish components of the cycle
A
Anaplerotic
