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Biochemistry > T1Q6 Cancer 2 > Flashcards

T1Q6 Cancer 2 Flashcards

1
Q

LOH

A

wh: loss of heterozygosity

causes:
mis-segregation results in tumor that is
a. monozygous in a heterozygous body
b. uniparental disomy
c. gene conversion
d. independent unrelated mutation (not TRUE loh)

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2
Q

gene conversion

A

?

unidirection exchange that is otherwise similar to homologus recombination

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3
Q

p16

A

wh: tumor supressor
mechanism: cyclin kinase inhibitor

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4
Q

TGFB pathway

A

a RTK signaling pathway that limits cell growth

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Biochemistry (15 decks)

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