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K Sun
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Decks in this class (15)
DNA Replication
Telomere,
Origins of replication,
Growing forks
18
cards
Transcription
Mediator complex,
Hats,
Atp dependent chromatin remodelin...
10
cards
Eukaryotic Transcription
Promoter proximal sequences,
Enhancers,
Regulatory factors
26
cards
Mendelian Inheritance III: Confounders
New mutations,
Germline mosaicism,
Delayed age of onset
9
cards
Medical Genetics: Clinical Cytogeneics
Cri du chat syndrome cry of the cat,
Cytogenetics,
Angelman s syndrome
12
cards
Medical Genetics: Genetic Mapping and Cloning
Linkage v association 3,
Strategy functional approach,
Strategy candidate gene
11
cards
Genetic Testing
1. Scope:
2. Techniques:
3. Risks and Benefits (see lecture notes)
14
cards
T1Q5: Apoptosis
Leaning Objectives
• understand necrosis vs. apoptosis
• understand the steps in apoptosis, and the proteins involved at each step
Key
wh- what
wy- why
wn- when
whr- where
25
cards
T1Q5: Epigenetics
• distinguish between epigenetic and genetic inheritance
• distinguish functional and structural differences between 2 heterochromatin
types and euchromatin
• understand how gene expression states can determine phenotype
• understand basic mechanisms and examples of epigenetic gene regulation
• understand overall principle of how imprinting works and how it can lead to
atypical inheritance patterns
18
cards
T1Q5: Cell Cycle
Define the stages of the mammalian cell cycle and describe how protein kinases
control the progression of the cell cycle.
• Define the four major checkpoints and understand what event they monitor.
21
cards
T1Q5 Signal Transduction I & II
1. understand the key properties of signal transduction pathways
2. understand the roles of protein phosphorylation; g-protein activation, and second messengers in signal transduction
3. describe several major signal transduction pathways
22
cards
T1Q6 Cancer 1
Oncogene,
Tumor supressor gene,
Gate keeper
17
cards
T1Q6 Cancer 2
Loh,
Gene conversion,
P16
4
cards
T1Q6 Cancer Inheritance
Cytogenetic observation,
Positional cloning,
Cloning
16
cards
Cancer 3
Mechanisms of oncogene activation,
Reciprocal translocation,
Inversion
7
cards
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Biochemistry
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