DNA Replication

Question 1

telomere

Answer 1

end of DNA, often repeating, protective

Question 2

origins of replication

Answer 2

a specific site of DNA synthesis in prokaryotes

Question 3

growing forks

Answer 3

sites of active DNA synthesis

Question 4

helicase

Answer 4

unwinds DNA. it looks beautiful

Question 5

binding protein (ssb)

Answer 5

binds single strands of DNA and prevents them from renealing

Question 6

primase

Answer 6

enzyme that makes RNA primer for DNA synthesis

Question 7

leading strand

Answer 7

strand continuously synthesized 5-3’

Question 8

lagging strand

Answer 8

strand discontinuously synthesized from 5’-3’ with okazaki fragments

Question 9

topoisomerase

Answer 9

bacterial, relieve stress through nicking and looping

Question 10

catenane

Answer 10

latine for “chain”; description of DNA’s shape with toposiomerase

Question 11

reverse transcriptase

Answer 11

make DNA from RNA, but are error prone due to lack of 3’->5’ exonuclease activity

Question 12

telomerase

Answer 12

reverse transcriptase that extends a telomere on the lagging strand. DNA pol fills in gap

Question 13

DnaA

Answer 13

a prokaryotic protein that initiates the origin of replication

Question 14

DNA pol I has ____ activity

Answer 14

has 5-3’ exonuclease activity

Question 15

okazaki fragments

Answer 15

600 base pairs, chunks used to form the lagging strand

Question 16

Tau subunit

Answer 16

forces coordination of lagging and leading strand synthesis

Question 17

backward slippage in the ____ causes ____

Answer 17

synthesized strand causes an insertion

Question 18

fordward slippage in the ____ causes _____

Answer 18

parental strand causes deletion