T cells at work Flashcards
What are cytoknes
proteins used for signals to the rest of the immune system
Do cytokines travel between cells or systemically
don’t travel far, travel locally
What are 3 types of helper T cells
Th1, Th2, Th17
What dictates the type of cytokines that the t cell expresses
The APC provides coaching including the type of invader and location of infection(different areas have different cytokine expression so APC remembers where it came from)
What types of infections do TH1 respond to
bacterial/viral infection
What are the 3 things that Th1 releases
- TNF
- IFN-gamma
- IL-2
What does release of IL-12 cause
TH1 cells
What types of infections do Th2 cells respond to
parasite and bacteria
Which cell does il-4 produce when released from Dendritic cell
Th2 cell
Which IL’s does Th2 make
IL-4, IL-5, IL-13
What does IL-4 produce
IgE class siwtching to address parasites
What does IL-13 stimulate
Mucus production against bacteria/parasitic infections
What types of infections do Th17 respond to
Fungi and extracellular bacteria
Which cytokine is most infalmmatory/most important in producing fever
IL-1- causes inflammation and fever in injuries and illness (specifically covid)
Main function of CD8
destroy APC that has viral infection
