Systemic Sclerosis

Question 1

A group of rare diseases that involve the hardening and tightening of the skin. Cutaneous Fibrosis.

Answer 1

Systemic Sclerosis/Scleroderma

Question 2

Two types of scleroderma

Answer 2

1. Systemic Sclerosis (Limited and Diffuse Scleroderma)
2. Localized Scleroderma

Question 3

Age affected

Answer 3

30 to 50 y.o.

Question 4

Pathological Processes of scleroderma

Answer 4

1. Excessive deposition of collagen
2. Non inflammatory vasculopathy
3. Alterations in cellular and humoral immunity

Question 5

Severe type of scleroderma in systemic sclerosis

Answer 5

Diffuse Scleroderma

Question 6

Mild type of scleroderma in systemic sclerosis

Answer 6

Limited Scleroderma

Question 7

CREST in limited scleroderma

Answer 7

1. Calcinosis
2. Raynaud’s phenomenon
3. Esophageal Dysfunction
4. Sclerodactyly
5. Telangieactasis