Osteomalacia

Question 1

It is termed as defective bone mineralization.

Answer 1

Osteomalacia

Question 2

Signs and Symptoms of osteomalacia

Answer 2

1. Generalized aching bone pain
2. Easy Fatigue
3. Proximal weakness
4. Periarticular tenderness

Question 3

Dx of osteomalacia

Answer 3

1, General demineralization with cortical thinning, stress fractures, looser’s zone, multiple old rib fractures.

Question 4

Tx of osteomalacia

Answer 4

1. Vitamin D replacement
2. Sunlight or sun exposure
3. Ca supplements

Question 5

Causes of Osteomalacia

Answer 5

1. Vitamin D related
2. Hypophosphatemia
3. Miscellaneous

Question 6

Low dietary intake, low sunlight exposure, malabsorption syndromes, increased renal clearance, increased catabolism, pseudovitamin D-deficient rickets, hereditary vitamin D-deficient rickets

Answer 6

Vitamin D-related cause of osteomalacia

Question 7

Tumor induced osteomalacia, genetic hypophosphatemic rickets syndromes, Fanconi’s syndrome, RTA type 2

Answer 7

Hypophosphatemia cause of osteomalacia

Question 8

Hypophosphatasia, aluminum intoxication, fluorosis, bisphosphonate overdose

Answer 8

Miscellaneous causes of osteomalacia