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Mycology & Virology > Systemic Mycoses > Flashcards

Systemic Mycoses Flashcards

1
Q

Other terms for Blastomycosis

A

Gilchrist’s disease
North America Blastomycosis

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2
Q

Ecological Niche of B. dermatitidis

A

Wet acid soil
Moist environments (wood, tree bark, rotting vegetation)

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3
Q

B. dermatitiidis is endemic in

A

Mississipi
Missouri
Ohio river and tributaries
Canada
Kentucky
Carolina
Appalachian region
Winsconsin

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4
Q

lesion of B. dermatitidis

A

chronic granulomatous and suppurative disease

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5
Q

lesions of B. dermatitidis are found in

A

skin
mucus membrane
lungs
bone
GUT

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6
Q

4 types of blastomycosis

A

Cutaneous
Pulmonary
Osteoarticular
Genitourinary

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7
Q

elevated macerated ill-defined scaly borders with central ulcer

A

skin cutaneous blastomycosis

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8
Q

70% of blastomycosis

A

cutaneous blastomycosis

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9
Q

deisseminated and has round pneumonia mass like density w/ air in bronchogram

A

pulmonary blastomycosis

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10
Q

where is osteoarticular blastomycosis found

A

spine, long bones, ribs

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11
Q

symptoms of osteoarticular blastomycoses

A

painful debilitating arthritisis
ostemyelitis

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12
Q

where does genitourinary blastomycosis occur

A

males
prostate
epididymis

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13
Q

stain of tissue specimen on Blastomyces diagnosis

A

H and E
Giemsa
GMS (black wall)
PAS (red internal structure)

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14
Q

2 antigens used in Blastomyces

A

A and B

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15
Q

more effective antigen in Blastomyces

A

A

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16
Q

used for skin testing and extracted from yeast form

A

Blastomycin

17
Q

immunology methods in blastomyces diagnosis

A
  1. Immunodiffusion tests
  2. Enzyme immunoassay
  3. Complement fixation
  4. Chemiluminiscent DNA probe
18
Q

Specificity of ID in Blastomyces

A

84-100%

19
Q

sensitivity of ID in blastomyces diagnosis

A

57-62%

20
Q

specificity of EIA in blastomyces diagnosis

A

98%

21
Q

sensitivity of EIA in blastomyces diagnosis

A

80

22
Q

what colonies need stringent lab procedures

A

white fluffy colonies

Mycology & Virology (10 decks)

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