Synthetic routes- reaction pathways Flashcards

1
Q

alkene to alkane

A

H2 + Nickel catalyst

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2
Q

product alkene + H2 + nickel catalyst

A

alkane

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3
Q

reactant alkene to haloalkane

A

hydrogen halide (such as HCl)

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4
Q

product alkene + hydrogen halide

A

haloalkane

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5
Q

reactant alkane to haloalkane

A

halogen and UV light

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6
Q

product alkane and halogen under UV light

A

haloalkane

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7
Q

reactant haloalkane to alcohol (1.,2.)

A

NaOH(aq)

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8
Q

product haloalkane and NaOH(aq)

A

alcohol (1.,2.)

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9
Q

(1,2) alcohol to haloalkane reactant

A

sodium halide catalyst and H2SO4

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10
Q

(1,2) alcohol + sodium halide catalyst + H2SO4 product

A

Haloalkane

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11
Q

alkene to (1,2) alcohol reactant

A

H2O steam and H3PO4

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12
Q

alkene + H2O steam + H3PO4 product

A

(1,2) alcohol

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13
Q

reactant (1,2) alcohol to alkene

A

H3PO4 or H2SO4 and heat

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14
Q

(1,2) alcohol + H3PO4 or H2SO4 and heat

A

alkene

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15
Q

haloalkane to nitrile reactant

A

CN- and ethanol

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16
Q

haloalkane + CN- and ethanol

A

nitrile

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17
Q

reactants Haloalkane to amine

A

NH3 and ethanol

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18
Q

haloalkane + NH3 and ethanol

A

amine

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19
Q

(1,2) alcohol to ester

A

carboxylic acid and conc. H2SO4 or acid anhydride

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20
Q

(1,2) alcohol + carboxylic acid and conc. H2SO4 or acid anhydride

A

Ester

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21
Q

Ester to carboxylate

A

OH- and heat

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22
Q

ester + OH- and heat

A

carboxylate

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23
Q

Ester to carboxylic acid

A

Dilute acid and heat

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24
Q

ester + dilute acid and heat

A

carboxylic acid

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25
Q

carboxylic acid to ester

A

alcohol and conc. H2SO4

26
Q

carboxylic acid + alcohol and conc. H2SO4

A

Ester

27
Q

Acyl chloride to ester

A

alcohol

28
Q

Acyl chloride + alcohol

A

ester

29
Q

Acyl chloride to 2° amide

A

Primary amine

30
Q

Acyl chloride + primary amine

A

2° amide

31
Q

Acyl chloride to 1° amide

A

NH3

32
Q

Acyl chloride + NH3

A

1° amide

33
Q

Acyl chloride to carboxylic acid

A

H2O

34
Q

Acyl chloride + H2O

A

Carboxylic acid

35
Q

carboxylic acid to acyl chloride

A

SOCl2

36
Q

carboxylic acid and SOCl2

A

Acyl chloride

37
Q

1° alcohol to carboxylic acid

A

K2Cr2O7/H2SO4 and reflux

38
Q

1° alcohol + K2Cr2O7/H2SO4 and reflux

A

Carboxylic acid

39
Q

nitrile to amine

A

H2 and Nickel

40
Q

nitrile + H2 and nickel

A

amine

41
Q

nitrile to carboxylic acid

A

H2O and HCl and heat

42
Q

nitrile + H2O and HCl and heat

A

carboxylic acid

43
Q

hydroxynitrile to carboxylic acid

A

H2O and HCl and heat

44
Q

hydroxynitrile + H2O and HCl and heat

A

carboxylic acid

45
Q

hydroxynitrile to amine

A

H2 and Nickel

46
Q

hydroxynitrile + H2 and Nickel

A

amine

47
Q

ketone to hydroxynitrile

A

NaCN(aq) and H+ (aq)

48
Q

ketone + NaCN(aq) and H+(aq)

A

hydroxynitrile

49
Q

aldehyde to carboxylic acid

A

K2Cr2O7/H2SO4 and reflux

50
Q

aldehyde + K2Cr2O7/H2SO4 and reflux

A

carboxylic acid

51
Q

aldehyde to hydroxynitrile

A

NaCN(aq) and H+(aq)

52
Q

aldehyde + NaCN(aq) and H+(aq)

A

hydroxynitrile

53
Q

aldehyde to 1° alcohol

A

NaBH4

54
Q

aldehyde + NaBH4

A

1° alcohol

55
Q

1° alcohol to aldehyde

A

K2Cr2O7/H2SO4 and distillation

56
Q

1° alcohol + K2Cr2O7/H2SO4 and distillation

A

aldehyde

57
Q

2° alcohol to ketone

A

K2Cr2O7/H2SO4 and reflux

58
Q

2° alcohol + K2Cr2O7/H2SO4 and reflux

A

ketone

59
Q

Ketone to 2° alcohol

A

NaBH4

60
Q

Ketone + NaBH4

A

2° alcohol