Synaptic transmission Flashcards
Explain me in a long answer the steps of the synaptic transmission
When the AP arrive at the end of the axon, the v-gated calcium channel opens. That lets in a great number of calcium that will act as messenger to trigger enzymes. The enzymes will help neurotransmitters to bind with vesicles. The vesicles will release its content by using exocytosis. The neurottransmitters will act on post synaptic receptors (indirect or direct).
Indirect, g-protein, series of event, open a ion channel somewhere else.
direct. goes straight in or out.
What is temporal summation and spatial summation
Temporal summation: One presynaptic neuron releases neurotransmitters over a period of time to fire an action potential
Spatial summation: Multiple presynaptic neurons release neurotransmitters together to fire an action potential