Pharmocology Flashcards

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1
Q

what is the first drug mechanism of action (sy)

A

synthesis:

a drug can act as precursor to increase NT effect.

or

it can inhibit enzymes to decrease NT effect.

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2
Q

what is the second drug mechanism of action (st)

A

Storage:

A drug can block a transporter to decrease NT in vesicle and stop its release.

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3
Q

what is the third drug mechanism of action (re)

A

Release:

a drug can act as docking protein in vesicle to increase NT

or

it can block the docking protein to decrease NT

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4
Q

what is the fourth drug mechanism of action (rec)

A

Receptor interaction:

Drugs can bind to receptors to either increase or decrease the NT effect.

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5
Q

what is the fifth drug mechanism of action (in)

A

Inactivation

drug can stop enzymes in the synaptic cleft to increase NT.

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6
Q

what is the drug mechanism of action (reu)

A

Reuptake

drug can block reuptake transporter to increase NT

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7
Q

what is the seventh drug mechanism of action

A

Degradation

a drug can stop the enzymes in the cell from degrading NT so agonist.

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8
Q

What is pharmokinetics (4 steps)

A

Absorption:
by bloodstream (indirect, slow by lipid soluble)
or
directly to the brain (fast)

Distribution:
the journey of the drug in the system through various tissues

Metabolism
7 mechanism / sites

Excretion.

enzymes

urine, feces, sweat, exhale, breast milk

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