Synaptic Structure and Function Flashcards
What different types of synapses are there?
Electrical
Chemical
Mixed
With regards to electrical synapses, how wide is the synaptic cleft?
3nm
What is the mediating agent in electronic synapses?
Ion current
What is the synaptic delay time in electronic synapses?
Little or none
Are electrical synapses uni or bi directional?
Bi-directional as they are based on concentration gradients
Which type of synapse are most of the brains synapses?
Chemical
With regards to chemical synapses, how wide is the synaptic cleft?
30-50nm
What is the mediating agent in chemical synapses?
A chemical messenger
What is the synaptic delay time in chemical synapses?
0.3 - 0.5msec
Are chemical synapses uni or bi directional?
Unidirectional
What is one way to classify synapses based on the thickness of the post-synaptic density thickness?
Symmetric or asymmetric synapses
What is the difference between grey type 1 and grey type 2 synapses?
Type 1 = round vesicles and large active zones (bits of the pre and post synaptic neurons which re close)
Type 2 = oval vesicles and small active zones
Where do type 1 and type 2 usually attach to post-ganglionic neurons?
Type 1 = end on shaft or spine
Type 2 = end on soma