Synapses Flashcards
Storage granule
Large compartment that holds synaptic vesicles
Electrical synapse
Gap junction; direct connection between two cells that allows passage of ions and other small molecules
Types of chemical synapses
1) dendrodendritic
2) axodendritic
3) axoextracellular
4) axosomatic
5) axosynaptic
6) axoaxonic
7) axosecretory
Resting potential is due to these three factors
1) intracellular excess of anions
2) K+ accumulates in cell
3) Na+ is pumped out of cell by pumps
Graded potential
Brief change in polarity that is local
Three ways to obtain graded potentials
1) movement of K+ ions
2) movement of Na+ ions
3) movement of Cl- ions
Hyperpolarization is due to…
K+ efflux or Cl- influx
Depolarization is due to…
Na+ influx
Action potential
Short event in which electrical membrane potential of a cell rapidly rises and falls following consistent trajectory
Tetramethylammonium (TEA) blocks…
K+ channels
Tetrodotoxin blocks…
Na+ channels
Digitalis blocks…
Na/K pumps
Node of Ranvier
Breaks in myelin sheath contains many voltage sensitive channels
How action potentials are passed on
1) action potential arrives at axon
2) voltage-gated Ca channels open and release Ca
3) causes vesicles to release contents
4) neurotransmitters diffuse across synaptic cleft and bind to ligand-gated ion channels
5) binding opens channels causing graded potentials
6) neurotransmitter is removed from cleft in various ways
Temporal summation
Graded potentials that occur at approximately the same time on a membrane are summed