Synapses Flashcards

1
Q

Storage granule

A

Large compartment that holds synaptic vesicles

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2
Q

Electrical synapse

A

Gap junction; direct connection between two cells that allows passage of ions and other small molecules

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3
Q

Types of chemical synapses

A

1) dendrodendritic
2) axodendritic
3) axoextracellular
4) axosomatic
5) axosynaptic
6) axoaxonic
7) axosecretory

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4
Q

Resting potential is due to these three factors

A

1) intracellular excess of anions
2) K+ accumulates in cell
3) Na+ is pumped out of cell by pumps

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5
Q

Graded potential

A

Brief change in polarity that is local

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6
Q

Three ways to obtain graded potentials

A

1) movement of K+ ions
2) movement of Na+ ions
3) movement of Cl- ions

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7
Q

Hyperpolarization is due to…

A

K+ efflux or Cl- influx

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8
Q

Depolarization is due to…

A

Na+ influx

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9
Q

Action potential

A

Short event in which electrical membrane potential of a cell rapidly rises and falls following consistent trajectory

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10
Q

Tetramethylammonium (TEA) blocks…

A

K+ channels

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11
Q

Tetrodotoxin blocks…

A

Na+ channels

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12
Q

Digitalis blocks…

A

Na/K pumps

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13
Q

Node of Ranvier

A

Breaks in myelin sheath contains many voltage sensitive channels

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14
Q

How action potentials are passed on

A

1) action potential arrives at axon
2) voltage-gated Ca channels open and release Ca
3) causes vesicles to release contents
4) neurotransmitters diffuse across synaptic cleft and bind to ligand-gated ion channels
5) binding opens channels causing graded potentials
6) neurotransmitter is removed from cleft in various ways

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15
Q

Temporal summation

A

Graded potentials that occur at approximately the same time on a membrane are summed

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16
Q

Spatial summation

A

Graded potentials that occur at approximately the same location and time on membrane are summed

17
Q

Parts of synapse

A
Presynaptic membrane
Postsynaptic membrane
Synaptic cleft
Microtubules
Mitochondria
Vesicles
Storage granules