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Psy 303 > Neurotransmitters > Flashcards

Neurotransmitters Flashcards

1
Q

Biochemical steps in Neurotransmission

A

1) synthesis
2) release
3) receptor action
4) inactivation

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2
Q

Ionotropic Receptors

A

Excitatory; ligand gated ion channels

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3
Q

Metabotropic Channels

A

Inhibitory; consist of receptor and G protein; can activate enzymatic cascade

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4
Q

Small Molecule Neurotransmitters

A

1) Acetylcholine (ACh)
2) Dopamine (DA)
3) Norepinephrine (NE)
4) Epinephrine (EP)
5) Serotonin (5-HT)
6) Glutamate (Glu)
7) Gamma-aminobutyric acid (GABA)
8) Glycine (Gly)
9) Histamine

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5
Q

Classes of Neurotransmitters

A

1) small molecule
2) peptides
3) gases

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6
Q

Amines

A

Phenylalanine ➡️Tyrosine ➡️ L-Dopa ➡️ Dopamine ➡️ Norepinephrine ➡️ Epinephrine

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7
Q

Glycine

A

Inhibitory transmitter in spinal cord

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8
Q

Excitatory Post Synaptic Potential

A

Neurotransmitter binding opens cation channels (Na, K, Ca)

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9
Q

EPSP often evoked by…

A

Glutamate (CNS) and Acetylcholine (PNS)

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10
Q

Inhibitory Post Synaptic Potential

A

Neurotransmitter binding opens Cl channels

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11
Q

IPSP often evoked by…

A

GABA (CNS) and Glycine (PNS)

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12
Q

Glutamate

A

Excitatory transmitter in Brian

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13
Q

Gamma-Aminobutyric Acid

A

Inhibitory transmitter in brain

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14
Q

Nitric Oxide

A

Stimulates smooth muscle of blood vessels to dilate

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15
Q

Carbon Monoxide

A

Intestinal relaxation

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16
Q

Cholinergic System

A

Maintains waking pattern of cortex and plays role in memory

17
Q

Death of cholinergic neurons related to…

A

Alzheimer’s

18
Q

Nigrostriatial Pathway

A

Maintains normal motor behaior

19
Q

Loss of dopamine in nigrostriatial pathway linked to…

A

Muscle rigidity in Parkinson’s

20
Q

Mesolimbic Pathway

A

Involved in reward and pleasure

21
Q

Increase of dopamine in mesolimbic pathway related to…

A

Schizophrenia

22
Q

Noradrenergic System

A

Maintains emotional tone

23
Q

Decrease in NE related to…

A

Depression

24
Q

Increase in NE related to…

A

Mania

25
Q

Serotonergic System

A

Maintains waking pattern

26
Q

Change in serotonin related to…

A

OCD, tics, and Schizophrenia

27
Q

Decrease in serotonin related to…

A

Depression

28
Q

Proofs for Neurotransmitter

A

1) in neuron
2) when released, produce response
3) artificial application mimics response
4) mechanism for removal is present

Psy 303 (16 decks)

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