Neurodegeneration Flashcards

1
Q

Apoptosis

A

Genetically programmed cell death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Misregulation and deposition of Tau correlates with

A

Frontotemporal dementia and Parkinsonism; Alzheimer’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Alpha Synuclien

A

Filamentous nonsoluble protein that maintains synaptic pool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Synucleinopathies

A

Disorders characterized by intracellular aggregation of alpha synuclein (Parkinson’s, disease with Lewy bodies)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Protein Degradation

A

Abnormal proteins aggregate and accumulate and clog proteasome causing dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Alzheimer’s Disease

A

Characterized by neurotic plaques (a-beta peptides) and neurofibrillary tangles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Acute Neurodegeneration

A

Stroke and Traumatic Brain Injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly