Neurodegeneration Flashcards
1
Q
Apoptosis
A
Genetically programmed cell death
2
Q
Misregulation and deposition of Tau correlates with
A
Frontotemporal dementia and Parkinsonism; Alzheimer’s
3
Q
Alpha Synuclien
A
Filamentous nonsoluble protein that maintains synaptic pool
4
Q
Synucleinopathies
A
Disorders characterized by intracellular aggregation of alpha synuclein (Parkinson’s, disease with Lewy bodies)
5
Q
Protein Degradation
A
Abnormal proteins aggregate and accumulate and clog proteasome causing dysfunction
6
Q
Alzheimer’s Disease
A
Characterized by neurotic plaques (a-beta peptides) and neurofibrillary tangles
7
Q
Acute Neurodegeneration
A
Stroke and Traumatic Brain Injury