Sympathomimetics

Question 1

When released into the organism, what receptor does noradrenaline mainly influence?

Answer 1

B1 receptors

Question 2

Why is the adrenal medulla an important component of the sympathetic nervous system?

Answer 2

It contains chromaffin cells that release epinephrine and norepinephrine (mediators) from the adrenal gland

Question 3

Adrenergic receptors a1 and a2: are they post or pre-synapse, and where are they mostly located in?

Answer 3

a1: postsynapse - most of all in arteries
a2: Presynapse - mostly on smooth muscle cells

Question 5

When released in the organism, what receptor does adrenaline mostly influence

Answer 5

Mostly B2, but also B1

Question 6

What is the general B1 mimetic effect

Answer 6

Increase in the heartbeat and heart contractility, lipolysis

Question 7

What is the general B2 mimetic effect?

Answer 7

Decrease in the tone of bronchial muscle

Question 8

What are some overall general B-mimetic effects

Answer 8

Glycogenolysis
Dilation of blood vessels in skeletal muscle
Decrease in GI motility
Relaxation of the uterine smooth muscle