Serotonin recap (FINAL)

Question 1

Where can Serotonin be found in

Answer 1

Autacoid - all over
Enterochromaffin cells of intestines
Neurons of CNS
Mast cells
Platelets

Question 2

Role of serotonin

Answer 2

Sleep-wake cycle
Thermoregulation
Behavior
Motility of intestines (peristalsis)

Question 3

What is SSRI?

Answer 3

Selective serotonin reuptake inhibitor
- Used to treat depression & behavioral issues
- Fluoxetine

Question 4

Serotonin antagonists

Answer 4

Against vomiting & GI irritation, nausea
- Ondansetron
Increase appetite
Inflammatory in respiratory tract (cyproheptadine)

Question 5

Serotonin agonists in vetmed

Answer 5

Used for constipation

Question 6

Toxicity of serotonin

Answer 6

Nausea, vomiting
Mydriasis
Hyperthermia
Salivation