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Virology > Swine Viruses > Flashcards

Swine Viruses Flashcards

1
Q

virus family of Hog Cholera

A
  • flavivridae
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2
Q

hog cholera also known as

A
  • classical swine fever
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3
Q

hog cholera affects swine of what age group and what is its morbidity and mortality

A
  • all ages

- high morbidity and mortality

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4
Q

T/F: Hog Cholera occurs in the US

A
  • false - was eradicated
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5
Q

T/F: severe leukopenia is always present with Hog Cholera

A
  • true
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6
Q

swine infected with Hog Cholera how does their skin change

A
  • hyperemia and purpura of abdomen and ears
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7
Q

T/F: young swine may die preacutley but they always show clinical signs before

A
  • false - they show no clinical signs
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8
Q

effect of Hog Cholera on pregnant Sows (4)

A
  • reabsorption
  • abortion
  • fetal mummification
  • still births
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9
Q

what disease of hog cholera is associated with extended or intermittent clinical disease

A
  • subacute and chronic
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10
Q

most common route of entry for Hog Cholera

A
  • ingestion
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11
Q

how does hog cholera create profound leukopenia and thrombocytopenia

A
  • 2nd replication in endothelial cells, lymphoid organs, bone marrow -> hemorrhages
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12
Q

pathognomonic lesion of Hog Cholera

A
  • infarction of spleen
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13
Q

most prominent lesion of Hog Cholera

A
  • general exhaustion of lymphoid system -> white cells are completely gone
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14
Q

what happens to pigs that are live born from a dam infected with Hog Cholera

A
  • are persistently infected
  • immunologically tolerant
  • life-long virus shedders
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15
Q

T/F: Hog Cholera is not notifiable

A
  • false - it should be notified
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16
Q

how is hog cholera transmitted

A
  • direct or indirect contact - avoid fomites
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17
Q

virus family of African Swine Fever (ASF)

A
  • asfaviridae
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18
Q

T/F: ASF needs it envelop to infect

A
  • false
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19
Q

which virus causes paracrystalline arrays in the cytoplasm of infected cells

A
  • African Swine Fever
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20
Q

what is the reservoir and vector of African Swine Fever

A
  • soft ticks
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21
Q

what are the 2 epidemiology of African Swine Fever

A
  • in warthog

- in domestic swine

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22
Q

T/F: severe leukopenia is a clinical sign of African Swine Fever

A
  • true
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23
Q

mortality rate of African Swine Fever

A
  • can be high in naive populations
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24
Q

where are gross lesions of African Swine Fever located

A
  • lymphatic and vascular systems
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25
Q

what clinical sign of African Swine Fever is also seen in Hog Cholera

A
  • enlarged friable spleen

- petecchia in cortex of kidneys

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26
Q

T/F: swine that survive African Swine Fever are free of disease

A
  • false - are persistently infected
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27
Q

T/F: there is a vaccination for African Swine Fever

A
  • false - hard to make because it does not need its envelope so it avoids producing neutralizing antibodies
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28
Q

viral family of pseudorabies

A
  • herpesviridae
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29
Q

T/F: pseudorabies does not exist in the wild pig population

A
  • false - it does in the southern states
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30
Q

pregnant sow infected with pseudorabies before day 30

A
  • resorption
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31
Q

pregnant sow infected with pseudorabies after day 30

A
  • abortion
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32
Q

pregnant sow infected with pseudorabies later

A
  • mixture of mummified, macerated, stillborn, weak and normal piglets
33
Q

mortality rates in piglets born to non-immune sows of pseudorabies

A
  • 100%
34
Q

weaned, growing and mature swine clinical signs for 4-8 days with pseudorabies

A
  • sneezing
  • coughing and fever
  • constipation and occasional vomiting
35
Q

day 5 of infection with pseudorabies

A
  • incoordination, muscle spasm, circling

- neurologic signs

36
Q

day 6-8 of infection with pseudorabies

A
  • moribund and die within 12 hours
37
Q

secondary host of pseudorabies - cattle clinical signs

A
  • pruritus “mad itch”

- progressive CNS involvement with death

38
Q

secondary host of pseudorabies - dogs clinical signs

A
  • no tendency to attack
39
Q

T/F: pseudorabies has viremia

A
  • false
40
Q

shedding of recovered pigs from pseudorabies

A
  • can shed continuously in nasal secretions
41
Q

diagnosis of pseudorabies

A
  • antibody ELISA
42
Q

T/F: pseudorabies can be shed in feces and urine as well as saliva and nasal discharge

A
  • false - only through saliva and nasal discharge
43
Q

virus family of Postweaning multisystemic wasting syndrome (PMWS)

A
  • circoviridae
44
Q

clinical signs of PMWS

A
  • multi-systemic wasting syndrome of weaned piglets
45
Q

3 forms of PMWS

A
  • reproductive failure (breeding)
  • respiratory disease in finishing pigs
  • porcine dermatitis and nephropathy syndrome
46
Q

T/F: PMWS can be shed in feces and urine as well as saliva and nasal discharge

A
  • false - is shed in the feces
47
Q

is there a vaccine for PMWS

A
  • yes - but is strain specific
48
Q

porcine parvovirus viral family

A
  • parvoviridae
49
Q

ages that porcine parvo effects and what dramatic effects can be seen

A
  • domestic swine of all ages

- dramatic effects in naive pregnant pigs (stillbirth, mummified, embryonic death, infertility)

50
Q

porcine parvo infection before 30 days of gestation

A
  • fetal death and resorbtion (EDI)
51
Q

porcine parvo infection between 30-70 days of gestation

A
  • usually stillbirth and mummified
52
Q

porcine parvo infection after 70 days of gestation

A
  • developing lesions
53
Q

porcine parvo effect on boars

A
  • low fertility
54
Q

pathogenesis of porcine parvo

A
  • replicates in tonsils, LN, thymus, spleen, lungs and other organs of fetus
  • also replicates in peripheral blood lymphocytes (monocytes & macrophages -> leukopenia)
55
Q

how many days does it take after infection for porcine parvo to reach the fetus

A
  • 15 days
56
Q

diagnosis of porcine parvo

A
  • IF of fetal tissues
57
Q

shedding of porcine parvo in boars

A
  • shed in semen
58
Q

vaccination window of porcine parvo

A
  • 7 months
59
Q

transmissible gastroenteritis (TGE) virus family

A
  • coronaviridae
60
Q

4 different diseases of TGE

A
  • transmissible gastroenteritis (TGE)
  • vomiting and wasting disease
  • porcine epidemic diarrhea
  • respiratory disease
61
Q

vomiting and profuse yellow diarrhea clinical signs of what virus

A
  • transmissible gastroenteritis (TGE)
62
Q

in older pigs clinical signs of transmissible gastroenteritis (TGE)

A
  • course is shorter and rarely any vomiting
63
Q

pathogenesis of transmissible gastroenteritis (TGE)

A
  • villous enterocytes of small intestines are destroyed -> shortening of villi
64
Q

why is recovery of transmissible gastroenteritis (TGE) fast

A
  • crypt cells are unaffected
65
Q

diagnosis of transmissible gastroenteritis (TGE)

A
  • gross lesions are limited to GI
66
Q

which antibodies are protective against transmissible gastroenteritis (TGE)

A
  • maternal IgA - protective

- systemic IgG - no protective

67
Q

swine vesicular disease virus family

A
  • picornaviridae
68
Q

swine vesicular disease has similar clinical signs as what other virus

A
  • FMD
69
Q

swine vesicular disease shed in what excretion

A
  • feces
70
Q

vesicular exanthema of swine virus family

A
  • caliciviridae
71
Q

from what disease is indistinguishable clinically from vesicular exanthema of swine

A
  • FMD
72
Q

swine influenza virus family

A
  • orthomyxoviridae
73
Q

entry of swine influenza

A
  • aerosol
74
Q

porcine reproductive and respiratory syndrome (PRRS) virus family

A
  • arteriviridae
75
Q

what virus persists well in environment even at low temperatures

A
  • porcine reproductive and respiratory syndrome (PRRS)
76
Q

transmission of porcine reproductive and respiratory syndrome

A
  • contact
  • airborne
  • sexual transmission via semen
77
Q

clinical signs of porcine reproductive and respiratory syndrome (PRRS)

A
  • blue discoloration of ears, snout, vulva
78
Q

T/F: a vaccine is available for reproductive and respiratory syndrome (PRRS)

A
  • true

Virology (8 decks)

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