Suture Material Flashcards
Natural
- biological origin
- causes intense inflammatory rxn
- chromic gut, silk
Synthetic
- synthetic polymer
- does not cause tissue rxn
- nylon, polymer (PDS, vicryl)
- most suture materials are synthetic!
Absorbable
- loss of tensile strength in 60-90 days
- degraded via inflammatory rxn or hydrolysis
- internal or buried sutures
Non-absorbable
- may eventually degrade
- potential nidus for infection
- external sutures
- intentional internal use (as a marker)
Monofilament
- single strand, parallel fibers
- less tissue drag –> less trauma!
- resists microorganisms
- ties smoothly
- requires more knots than braided
- possesses memory
Multifilament
- fibers are twisted (braided)
- greater resistance in tissue –> drag
- provides good handling and ease of typing
- fewer knots required
Capillary action, increased infection risk, less smooth, less strength, better handling and knot security
Braided
No capillary action, less infection, smooth tissue passage, higher strength, memory, more throws
Monofilament
Surgical catgut
Submucosa of sheep SI or serosal layer of bovine SI
- multifilament (resembles monofilament)
- absorbed via phagocytosis –> slowed by chromic salt
- > 90 days to absorb, but becomes significantly weak
- poor knot security
- good handling
- cannot be autoclaved! –> radiation or ethylene oxide
Plain vs chromic gut
- plain: loss of >67% strength by 7 days
- chromic: loss of 50% strength by 7 days, 83% by 14 days, 100% by 21 days
Polydioxanone (PDS)
Loss 26% strength by 14 days, 42% by 28 days, 86% by 56 days
Polyglyconate (PGT, MAXON)
Polymer of polytrimethylene carbonate and glycolic acid
- loss 19% strength by 14 days, 41% by 28 days
PDS and Maxon - characteristics
- monofilament
- degraded via hydrolysis
- excellent tensile strength –> is initially better than nylon and polypropylene
- good knot security
- little/no tissue rx
- memory
- minimal tissue drag
What is commonly used to close the body wall and linea alba?
PDS, Maxon
Poliglecaprone 25
PGC25, Monocryl
- synthetic, monofilament
- absorbed by hydrolysis –> complete by 90-120 days
- loss of 50% strength by 10 days, 100% by 21 days
- good knot security
- minimal/no tissue rxn
- good tissue handling
- no drag
What is used as a buried suture?
Monocryl
Polyglactin 910
PG910, Vicryl
- polymer of glycolic acid and lactic acid in a ratio of 9:1
- multifilament
- absorbed via hydrolysis –> rate is increased in an alkaline environment and at higher temps!!!
- complete absorption by 40-90 days, independent of suture size
- good tensile strength –> lost 50% by 14 days, 80% by 21 days
- little/no tissue rxn, considerable tissue drag
Silk
Cocoon of silk worm, dyed black
- multifilament, treated with oil to reduce capillarity
- nonabsorbable, some breakdown over time
- slow loss of strength –> 30% by 14 days, 50% at 1 year, 100% by 2 yrs
- good knot security
- some tissue rxn via ulceration of GIT lumen
- gold standard of handling characteristics
Stainless steel
Surgical grade, alloy of chromium, nickel, and molybdenum
- mono or multifilament
- nonabsorbable
- highest tensile strength of any suture!!
- greatest knot security of all suture!
- poor handling
- used in infected surgical sites
Nylon
Amine coated thermoplastic
- mono or multifilament
- nonabsorbable
- intermediate in strength
- monofilament will lose tensile strength by 30% after 2 yrs
- multifilament will lose tensile strength by 70-90% by 180 days
- memory!
Polymerized caprolactam
Polyamide suture of nylon family (vetafil, supramid, braunamid)
- coated in proteinaceous material
- multifilament, nonabsorbable
- loses 15-20% strength when wet!
- coating can break with repeated sterilization
- autoclave reduces strength, no chemical sterilization with disinfectants, dispensing vials are not sterile
Polyester fibers
Mersilene, dacron, polydek, tevdek
- multifilament, nonabsorbable
- high initial strength
- uncoated drag, good knot security
- coated less drag, poor knot security
- significant tissue rxn, greatest of all sutures!!!
Polypropylene
Prolene, flurofil
- monofilament
- nonabsorbable
- fair-poor tensile strength and knot security
- biologically inert
- least thrombogenic of any suture (often used in vascular surgery)!!
- poor handling, memory