Surgery Flashcards
What investigations are needed pre breast surgery
Need to determine if axillary lymphadenopathy
- if no lymphadenopathy do USS
- if palpable lymphadenopathy or sentinel node biopsy positive then need to resect
What is problem of axillary lymph node removal
Lymphoedema
Functional arm impairment
What do if USS of axillary lymph nodes negative
Sentinel lymph node biopsy in the operation
What tumour characteristics imply mastectomy over wide local excision
Multifocal tumour
Central location
Large lesion in small breast
DCIS over 4cm
Who is radiotherapy offered to in breast cancer
All woman whove had
- Had wide local excision
- Had T3-T4 mastectomy
Aim to reduce recurrence
What determines the choice of hormonal therapy in breast cancer
Pre or peri menopausal give tamoxifen
Post menopausal give letrozole
First line investigation for testicular cancers
USS
What tumour markers are released by the testicular cancers
Seminomas= HcG- but most often not elevated
Non-seminomas- AFP and HCG
LDH produced by most germ cell tumours and seminomas
Who is eligible for AAA screening
Men get a single abdo USS when they reach 65
Risk is 9:1 compared to women
How does follow-up from AAA screening work
Under 3cm= no action
3-4.4cm (small) = rescan every 12 months
4.5-5.4cm (medium) = rescan every 3 months
5.5cm and higher= refer within 2 weeks to vascular surgery
What makes an aneurysm low vs high rupture risk
Low
- under 5.5cm
- asymptomatic
High
- over 5.4cm
- symptomatic
- enlarging by over 1 cm a year
Management of low risk AAA
Elective vascular review
Rescan based on size
Optimise CVD rfx
Management of high risk AAA
Includes symptomatic and enlarging by 1cm a year
- refer within 2 weeks
- elective endovascular repair
How manage over 45 yo male who is treated for a UTI but the haematuria persists
Refer to urology under 2ww
What are 2 urological 2ww pathways
45 and over with isolated visible haematuria or persistent post UTI haematuria
60 and over with non-visible haematuria along with dysuria or a raised WCC
Risk factors for RCC
Middle aged men
Smoking
Von-hippel lindau
Tuberous sclerosis
APCKD- only slight increase tho
How can RCC present
Classic triad- haematuria, abdo pain and abdo mass
PUO
Varicocele as obstructing veins
Endocrine- EPO causing polycythaemia, ACTH and PTHrp
Cholestasis from stauffer syndrome
Renal vein thrombosis
Management of RCC
Mainstay is surgery
- under 7cm can do partial nephrectomy
- over 7cm total nephrectomy
Immune modulators
- IL-2
- interferon alpha
Biologics
- receptor tyrosine kinase inhibitors- sorafenib
- ipilimumab
- novolimumab
What is ABPI
Ankle brachial pressure index is ratio of systolic blood pressure in the leg to that of arm
What is a normal ABPI
0.9-1.2
What ABPI indicates PAD vs severe disease
0.5-0.8- PAD
<0.5- severe disease
What can cause ABPI>1.2
Calcified, stiff arteries especially in elderly and DM with PAD
What are the types of lower urinary tract symptoms
Obstructive (voiding)
- weak flow
- straining
- hesitancy
- incomplete emptying
Storage
- urgency
- frequency
- incontinence
- nocturia
Post micturition
- dribbling
Complications
- retention
- UTI
- obstructive uropathy
How does tamsulosin and doxazoscin work
Alpha-1-antagonist
Reduces muscle tone of prostate and bladder
Side effects of tamsulosin
Dizziness
Dry mouth
Depression
Postural hypotension
How does finasteride work
5 alpha reductase inhibitors
Blocks conversion of DTH to testosterone which reduces prostate volume
Side effects of finasteride
Erectile dysfunction
Reduced libido
Gynaecomastia
What is management of predominantly voiding symptoms
First line- conservative measures or active monitoring
Second line if IPSS over 8 then alpha blocker
If fails to respond consider referral for surgery or catheter
What do if man has an enlarged prostate and is at high risk of progressing
Finasteride
When are both finasteride and tamsulosin indicated
bothersome moderate-to-severe voiding symptoms and prostatic enlargement
What is critical limb ischaemia
End stage of peripheral vascular disease when symptoms are present at rest. Associated with ulcers and gangrene
What are the 6 Ps
Pulseless
Paralysis
Parasthesia
Perishingly cold
Pain
Pale
What indicates embolus over thrombous as cause of acute limb ischaemia
Sudden onset with no preceding pain
AF or recent MI
Aneurysm proximal to pain
No evidence of contralateral symptoms
Initial acute limb ischaemia management
ABC
IV opioids
IV unfractionated heparin particularly if awaiting intervention (ischaemia takes 6 hours for leg to become unviable)
Vascular review for surgical intervention
First line investigation for suspected prostate cancer
Multiparametric MRI
What is used to determine if do transrectal ultrasound guided biopsy based off multiparametric MRI
Likert scale
If 3 or more then do TRUS
If 1-2 discuss with patient doing one
How to differentiate psychogenic cause from organic in case of erectile dysfunction
Psychogenic will have;
Sudden onset
Decreased libido
Major life events
Good erection by self
Investigation for erectile dysfunction
Measure morning testosterone and assess 10 year cardiovascular risk
If testosterone low or borderline then do full hormone profile
First line for erectile dysfunction
Phosphodiesterase type 5 inhibitor like sildenafil/viagra
What do if sildenafil contraindicated
Use vacuum erection device
What do if present with erectile dysfunction they have always had from puberty
Refer to urology
Breast cancer 2WW referral
Over 30 with unexplained lump
Over 50 with discharge, retraction or any other change in 1 breast
Skin changes indicative of cancer
Lump in axilla if over 30
What is done if predominantly storage problems
Lifestyle bladder training
First drug is oxybutynin
What do if mixed voiding and storage symptoms
Alpha blocker first
Second line add oxybutynin
What is used to manage thrombophlebitis
Consider vasc referral if long saphenous vein or high suspicion of DVT
Mild- topical NSAIDS with warm compresses
Severe- oral NSAIDS
Use compression stockings too to reduce DVT progression (check ABPI)
Consider LMWH too
Investigation for superficial thrombophlebitis
Arrange a duplex USS to rule out DVT
Problems of thrombophlebitis
Can lead to DVT
May indicate underlying DVT
How to investigate acute limb ischaemia
Initially do doppler
Then move onto duplex
Discharge differene between duct ectasia and intraductal papilloma
Duct ectasia= green and thick
Intraductal papilloma= clear or bloody
What does ultrasound of axillary lymph nodes showing snowstorm sign show
Ruptured implant
This is the leakage of silicone which enters lymphatics
What analgesia use for renal stones
NSAIDs
IM if need admission
Imaging for renal stones
Non contrast CTKUB to do within 14 hours
Management of kidney stone under 5mm
Watchful waiting for 4 weeks
Unless renal transplant, obstruction or renal anatomical abnormality
Management if obstructed kidney stone with infection
IV abx
Renal decompression with nephrostomy tube placement
Management of stones under 2cm
Lithotripsy
If pregnant uteroscopy
Management of complex renal calculi including staghorn
Percutaneous nephrolithotomy
What renal tumour is associated with chemicals from the textiles industry
Transitional cell
Management of ruptured abdominal aorta
Immediate vascular review
Control BP (do not want too high)
If haem unstable take straight to surgery for laparotomy
If stable may take to CT to assess if can do endovascular repair
Who should be referred to urology for prostate cancer
50-69
- PSA over 3
- abnormal DRE
Normal PSA range
50-59= under 3
60-69= under 4
Over 70= under 5
What falsely raises PSA
Prostatisis/UTI- wait 4 weeks
Ejaculation in last 2 days
Vigorous exercise in last 2 days
What organisms causes epididymo orchitis
Either local spread of STI
- chlamydia
- gonorrhoea
From bladder
- E coli
Investigations for epididymo orchitis
If young
- assess for UTI
If older
- MSU and urine dip
Management of epididymo orchitis
If young/STI suspected
- refer to GUM who will prescribe Ceftriaxone IM one dose and Doxycycline BD 14 days
If older and E coli suspected
- oral quinolone for 14 days
What do if recurrent balanitis
Circumcision
Management of hydrocele
Do USS to exclude cancer
Conservative approach
Management of varicocele
If mild then conservative
If large and symptomatic can consider surgery
How does fat necrosis present
Fat women with large breasts
Typically follows trauma
Irregular firm lump
Nipple changes seen
Presentation of acute prostatitis
Pain can be back, rectum or abdominal
Fever
Pain on defaecation
Voiding symptoms
Tender boggy prostate on examination
Management of prostatitis
Quinolone 14 days
Management for localised prostate cancer
If not advanved
- Can use watchful waiting
- Radical prostatectomy
- Radiotherapy
If more advanced
- radiotherapy
- prostatectomy
- hormone therapy
Complication of prostatectomy
Erectile dysfunction
Side effects of prostate radiotherapy
Proctitis
Bladder and colon cancer risk increased
What is main option for metastatic prostate cancer
Hormone therapy
Hormone therapy for prostate cancer
Aim is to reduce testosterone
GNRH agonists (goserelin) but this can initially cause flare of tumour
What causes urethral stricture
Idiopathic
Post STI
Penile fractures
Catheters
Management of urethral stricture
Dilation
What is complication post relief of retention
Diuresis which may lead to hypovolaemia, hyponatraemia
What can cause intermittent 10/10 pain in testicules
It is possible to get intermitten torsion which self resolves
Must treat with emergency fixation
Complications of transurethral resection of prostate syndrome
TURP syndrome
Urethral stricture
Retrograde ejaculation
Perforation of prostate
What is in TURP syndrome
Leakage of irrigation fluid (glycine) enters bloods causing a triad of
- hyponatraemia (dilutional)
- fluid overload
- glycine toxicity
If AFP and HCG not raised, what tumour is most likely cause
Seminoma
What is most common cause of testicular lump
Epididymal cyst
What is presentation of epididymal cyst
Separate from body of the testicle
Posterior to testicle
Painless lump
What are the types of urinary retention
Chronic
- low pressure
- high pressure
Acute
What causes acute onset pain in testes with retained cremasteric function
Torsion of testicular appendage
Gold standard investigation for AAA
CT Angio
Investigation if want to intervene on intermittent claudication
MRI angiogram
What is anti-platelet for PAD
Clopidogrel
Given for all patients with evidence of PAD
Medications given for PAD
Everyone is given atorvastatin 80mg and clopidogrel
Management of critical limb ischaemia
Urgent vascular referral
Analgesia
Urgent revascularisation
- endovascular angioplasty
- endarterectomy
- bypass
- amputation
What is management if fixed mottling of leg
Amputation
What is marjolins ulcer
A squamous cell carcinoma which occurs at the site of chronic inflammation such as ulcers
What can be done for severe intermittent claudication
Endovascular revascularisation
- angioplasty
Surgical revascularisaton
- endarterectomy
- bypass with autologous vein
What differentiates between doing endovascular vs open revascularisation on PAD
Endovascular indications
- stenosis under 10cm
- only 1 lesion
- around the iliac area
Surgical indications
- over 10cm
- multifocal lesions
- common femoral and more distally
If pain in buttocks on walking, in what vessel is there stenosis
Iliac
If there is pain in calves which artery is being affected
Superficial femoral
What may cause an ulcer to increase in size
Squamous cell carcinoma
Complications of varicose veins
Bleeding
Thrombophlebitis
Venous ulceration
DVT
What skin changes are seen in varicose veins and venous ulcers
Haemosiderin deposition-> hyperpigmentation
Lipodermatosclerosis-> hard/tight skin
Atrophie blanche-> hypopigmentation
Investigation for varicose veins
Venous duplex USS showing retrograde venous flow
Management of varicose veins
First line
- compressoin stockings
- weight loss
- exercise
- emollient
- elevate legs
If referred
- endothermal ablation
- surgery
- foam sclerotherapy
When refer to secondary care for varicose veins
Significant bothersome symptoms
Previous bleeding from varicose veins
Skin changes suggesting venous insufficiency
Superficial thrombophlebitis
Active or healed venous ulcer
What is cervical rib
When an extra rib can develop from the seventh vertebra
Presentation of subclavian steal syndrome
Come on when using arm
Syncope
Lightheadedness
Neuro symptoms can vary
Arm symptoms like crmaping on use or signs of PAD
What is rib notching on CXR indicative of
Aortic coarctation
Management of PAD
Atorvastatin 80mg
Clopidogrel
Exercise training
Investigation of choice by vascular for PAD
MR angio
In the legs MR angio> CT as vessels are smaller
Presentation of cervical rib
Compression of brachial plexus can lead to neuro symptoms in hand and arm
Worse when arms above head
Sudden onset collapse and cold, painful arm
Axillary artery embolus
What do for someone with terminal unresectable pancreatic cancer causing jaundice
Biliary stenting
What imaging is needed in pancreatitis
USS early to determine if cause is gallstones which will affect maangement
When is a right hemi-colectomy done
Caecal cancer
Ascending colon
Proximal transverse
When is a left hemi-colectomy indicated
Distal transverse colon
Descending colon
What operation is done for a sigmoid cancer
High anterior resection
What operation is done for high and mid rectum cancers
Anterior resection with total mesorectal fat excision
What is an anterior resection
Where remove all of the sigmoid/rectum depending on cancer location
What is a total mesorectal excision
Where remove all of the fat and lymph/blood around the rectum
What operation is done for anal cancer
Abdomino-perineal excision of the rectum with end colostomy bag
What operation is done in low rectal cancers
If within 5cm of of anal verge then APE
What do if HNPCC causing cancer
Panproctocolectomy which removes all of the colon to anus. End ileostomy prementantly created
What operation is done for sigmoid rupture and diverticulitis
Hartmanns
What counts as clear fluids
Water
Black tea or coffee
Ice lollies
Juice without pulp
Triad for gastric volvulus
Non-bilious vomiting
Pain
Failed attempts at getting NG tube in
What is management of fibroadenoma
Leave alone unless over 3cm when surgical excision can be used
What causes pain and swelling of the testis post urological intervention
Epididymo orchitis
When are hartmanns done
Emergency rupture or diverticulitis
What is a hiatus hernia
Herniation of stomach above diaphragm
How are most hiatus hernias found
Incidentally on endoscopy as nature of smyptoms makes them be investigated
What is best test for hiatus hernia
Barium swallow
Management of hiatus hernia
Conservative- all patients weight loss etc
If needed omeprazole or if reallt needed if very sympomatic- laprascopic fundoplication
What is ASA 1
Healthy non-smoking or minimal alcohol
What is ASA 2
Mild diseases without substantive functional limitation
Examples of ASA 2
Current smoker
Controlled DM and HTN
Mild lung disease
What is ASA 3
Patient with severe systemic disease
Examples of ASA 3
Poorly controlled DM, HTN and COPD
Alcohol dependance
Moderate EF reduction
BMI over 40
Active hepatitis
History of stroke or MI over 3 months ago
Renal disease on regular dialysis