Surgery Flashcards
What investigations are needed pre breast surgery
Need to determine if axillary lymphadenopathy
- if no lymphadenopathy do USS
- if palpable lymphadenopathy or sentinel node biopsy positive then need to resect
What is problem of axillary lymph node removal
Lymphoedema
Functional arm impairment
What do if USS of axillary lymph nodes negative
Sentinel lymph node biopsy in the operation
What tumour characteristics imply mastectomy over wide local excision
Multifocal tumour
Central location
Large lesion in small breast
DCIS over 4cm
Who is radiotherapy offered to in breast cancer
All woman whove had
- Had wide local excision
- Had T3-T4 mastectomy
Aim to reduce recurrence
What determines the choice of hormonal therapy in breast cancer
Pre or peri menopausal give tamoxifen
Post menopausal give letrozole
First line investigation for testicular cancers
USS
What tumour markers are released by the testicular cancers
Seminomas= HcG- but most often not elevated
Non-seminomas- AFP and HCG
LDH produced by most germ cell tumours and seminomas
Who is eligible for AAA screening
Men get a single abdo USS when they reach 65
Risk is 9:1 compared to women
How does follow-up from AAA screening work
Under 3cm= no action
3-4.4cm (small) = rescan every 12 months
4.5-5.4cm (medium) = rescan every 3 months
5.5cm and higher= refer within 2 weeks to vascular surgery
What makes an aneurysm low vs high rupture risk
Low
- under 5.5cm
- asymptomatic
High
- over 5.4cm
- symptomatic
- enlarging by over 1 cm a year
Management of low risk AAA
Elective vascular review
Rescan based on size
Optimise CVD rfx
Management of high risk AAA
Includes symptomatic and enlarging by 1cm a year
- refer within 2 weeks
- elective endovascular repair
How manage over 45 yo male who is treated for a UTI but the haematuria persists
Refer to urology under 2ww
What are 2 urological 2ww pathways
45 and over with isolated visible haematuria or persistent post UTI haematuria
60 and over with non-visible haematuria along with dysuria or a raised WCC
Risk factors for RCC
Middle aged men
Smoking
Von-hippel lindau
Tuberous sclerosis
APCKD- only slight increase tho
How can RCC present
Classic triad- haematuria, abdo pain and abdo mass
PUO
Varicocele as obstructing veins
Endocrine- EPO causing polycythaemia, ACTH and PTHrp
Cholestasis from stauffer syndrome
Renal vein thrombosis
Management of RCC
Mainstay is surgery
- under 7cm can do partial nephrectomy
- over 7cm total nephrectomy
Immune modulators
- IL-2
- interferon alpha
Biologics
- receptor tyrosine kinase inhibitors- sorafenib
- ipilimumab
- novolimumab
What is ABPI
Ankle brachial pressure index is ratio of systolic blood pressure in the leg to that of arm
What is a normal ABPI
0.9-1.2
What ABPI indicates PAD vs severe disease
0.5-0.8- PAD
<0.5- severe disease
What can cause ABPI>1.2
Calcified, stiff arteries especially in elderly and DM with PAD
What are the types of lower urinary tract symptoms
Obstructive (voiding)
- weak flow
- straining
- hesitancy
- incomplete emptying
Storage
- urgency
- frequency
- incontinence
- nocturia
Post micturition
- dribbling
Complications
- retention
- UTI
- obstructive uropathy
How does tamsulosin and doxazoscin work
Alpha-1-antagonist
Reduces muscle tone of prostate and bladder