Surgery Flashcards
ER + Breast cancer in post-menopausal
Anastrozole
Management of Barrett’s
Surveillance + High dose PPI
Dysplasia in Barrett’s
Endoscopic mucosal resection or radiofrequency ablation
Metabolic acidosis, elevated lactate and thumbprinting sign
Ischemic Colitis
Gold standard for ischemic colitis
CT
COCP should be stopped for how long before surgery
4 weeks
Painless jaundice
Pancreatic cancer
Crohn’s and Goblet cells
increased
Bloody diarrhea in IBD
UC
crypt Abscess
UC
pseudopolypoid appearance
UC
Hypercalcemia in pancreatitis
Cause of pancreatitis
hypocalcemia in pancreatitis
severity
Halitosis and Episodic dysphagia
pharyngeal Pouch
Barrett’s increases the risk of what cancer
adenocarcioma
Dysphagia to solids and liquids from the start
Achalasia
Treatment of Achalasia (surgical)
Hellers cardiomyotomy
Rovsig’s sign
Palpating LIF pains the RIF
Appendictomy requires prophylactic Abx T or F
True
Anal sphincter cancer
APER
Rectum
Anterior resection
Unstable and acute patient with colon cancer
Hartmann’s procedue
Painless jaundice and palpable GB
Pancreatic Cancer
Halo sign on mammogram
Breast cyst
Slit like retraction of the nipple
Duct ectasia
Small AAA
3 to 4.4 cm - rescan every 12 months
Medium AAA
4.5 to 5.4
rescan every 3 months
large AAA
> =5.5 cm refer within 2 weeks
AAA screening
Single abdominal USS at 65
Pharyngeal pouch treatment; Presenting with Dysphagia, regurgitation and halitosis
Surgery
Gold standard investigation for Aortic dissection
CT angiography of the chest, abdomen and pelvis (CTA-CAP)
Anastrazole side effects
Osteoporosis (most imp); hot flushes, insomnia and myalgia
Biliary colic pain radiates to
Interscapular region
Ileocecal resection causes what deficiency; It may cause glossitis
Vitamin B12 deficiency
Type of Shock
PAP low
CO low
SVR high
Hypovolemia
Type of shock
PAP high
CO low
SVR high
Cardiogenic shock
Type of shock
PAP low
CO high
SVR low
SEPTIC SHOCK
Smoker, infection of breast (recurrent); induration of the nipple areole
Periductal mastitis
Bright red bleeding, much-epithelial defect in the posterior midline of the anus; what is the diagnosis and what is the surgical management
Anal fissure - Sphinctertomy
Haemorrhoids - Painless, bleeding and pruritus
Rubber band ligation
What is seton insertion used for
Anal fistula
6 Ps of acute limb ischemia
Pale, pulseless, pain, perishing cold, paralysis and paraesthesia
Aortic dissection on imaging
CXR: widened mediastinum
CT angiography: False lumen
Poor weight gain, young infant, erythematous blanching rash, colicky abdominal pain, vomiting after feeds
Cows milk protein intolerance
PAD chronic management drugs
Statin + clopidogrel
Treatment of Achalasia
Pneumatic balloon dilation
Heller cardiomyotomy- surgery
Surgical management of GORD (severe)
Nissan Fundoplication
Rovsing’s Sign in appendicitis
RIF pain on palpation of LIF
Caecal, ascending or proximal transverse colon
Right hemicolectomy
Distal transverse, descending colon
Left hemicolectomy
Sigmoid colon
Higher anterior resection
Upper rectum
Anterior resectiom TME
Lower rectum
Anterior resection low TME
Anal verge
APER
Paralytic lieus management
Insert an NG tube
UC with avoiding stoma
Panproctocolectomy and ileoanal pouch
Only treatment for asystole
Adrenaline
All patients with an unprovoked DVT must be offered this test
CT scan abdomen and pelvis to identify possible cancer
All patients with mechanical valves require treatment with
Aspirin and Warfarin
scale formation at sites of minor injury and typically when injury is healing; can last months to week
Psoriasis
Airway that protects lungs from regurgitated stomach contents
Tracheal tube
Severe headache 24 hours after spinal anaesthetic
Low pressure headache
Cyclical pain, FNA- fluid, brown, no malignant change, 6 month history
Fibrocystic disease
CXR shows mediastinal surgical emphysema; air and fluid level in pleural cavity
Perforation of esophagus
Narrowed tubular structure; Food to fluid dysphagia, may be malnourished or cachectic
Oesophageal strictures
GOJ enters the thorax (sphincter)
Sliding hiatus hernia
proximal part of stomach herniates into thorax
Rolling hiatus hernia
Investigation of Hiatus hernia
barium swallow
Surgical management of hiatus hernia
Open/laparoscopic Nissen’s Fundoplication; indicated in rolling hiatus hernia due to risk of volvulus
Risk factors of oesophageal cancer
smoking, alcohol, diet, Barrett’s and achalasia
Acute management of varices
Clotting abnormalities, IV terlipressin, OGD + sclerotherapy or banding of varices
Prophylaxis of varices
Beta blockers + OGD + sclerotherapy/banding
TIPSS
Achalasia can be mimicked by this disorder
Chagas Disease (T. Cruzi)
Test for Achalasia
Barium swallow (Birds beak) and proximal dilatation
treatment of Achalasia - Endoscopic and medical
Endoscopic pneumatic dilatation or Botulinum Toxin injection at OGD
Surgical treatment of Achalasia
Heller’s operation
Protrusion through Killian’s Dehiscence is called
Pharyngeal pouch or Zenker’s Diverticulum
Surgical management of duodenal ulcer
suture ligation + vagotomy and pyloroplasty
Malignanct peptic ulcer surgery
Distal gastrectomy - Billroth
Bleeding proximal to this anatomical structure is classified as Upper GI bleeding
Ligament of Treitz
Upper GI bleeding mortality score
Rockall score
surgical treatment of pyloric stenosis
Ramstedt pyloromyotomy (incision of pylorus muscle)
Persistence of segment of the vitello-intestinall duct is called
Meckel’s Diverticulum
complicated diverticulitis surgical management
Hartmann’s procedure and colostomy reversal 3-6 months later
Tumour markers of colon cancer
CEA and CA19-9; Faecal occult blood
classification in colon cancer
Modified Dukes criteria
FAP genetics
Autosomal dominant
APC gene
Painless bright red PR bleeding, perianal lump and pruritus Ani
Hemorrhoids
Management of hemorrhoids
Grade 1-3: sclerosant injection/ banding/cryotherapy
grade 4: hemorrhoidectomy
painful anal tear and mucosa, posterior to midline, bright red PR bleeding, skin tags
Fissure
GTN cream, botox
Surgery: lateral sphincterotomy
constipation + Colicky pain + distention and vomiting
Complete bowel onstruction
Tinkling bowel sounds
SBO
SBO and stragulation
laparotomy
Intussuception management
Reduction with air enema
Cholangiocarcinoma is associated with
PSC; IBD
CA19-9
Pancreatic cancer
ABPI
> 1 normal
0.9-0.6: claudication
0.6 to 0.3: rest pain
<0.3: critical ischemia
buttock claudication + impotence
Aorto-iliac disease - Leriche’s Syndrome
Inflammed medium sized vessels; male smokers and occlusion
Buerger’s disease aka Thromboangiitis Obliterans
Unilateral temporary blindness due to carotid emboli
Amaurosis fugax
painful at rest, punched out, poor pulses, pallor cyanosis
Arterial ulcers
Ischemic limb and ulcer - Investigation
Biopsy and revascularization or amputation
DVT history, venous eczema, lipodermatosclerosis, pain when dressing are applied; gaiter distribution
compression bandaging
Marjolin’s Ulcer
Squamous cell carcinoma in ulcer, venous ulcer, biopsy is needed; excise
What type of dissection starts at the origin of left subclavian artery
Type B
fibroepithelial neoplasm; majority are benign but can be malignant, firm breast lump
phyllodes tumor
Most common breast carcinoma in situ
DCIS
Lobar carcinoma in situ needs bilateral or unilateral excision?
Bilateral
Eczematous skin change to the nipple; associated to a lump
Paget’s
Commonest post op complication within first 24 hours is
Reactionary hemorrhage
5-7 days post op most likely complication
WOund infection
Circulating volume less than capacity of IV compartment
is common to all forms of shock
Most useful guide to monitor fluid replacement
Urine output
Triple assessment
History and exam + Imaging + Biopsy/FNA
Most common cause of bleeding from the nipple
Duct papilloma
Most indicative of Appendicitis
McBurney’s point
Multiple fluid levels in small bowel + Air in biliary tree
Gallstone lieu’s
Calf symptoms
Superficial femoral occlusion
History of vascular disease, absent bowel sounds, abdominal pain, lactic acidosis (key sign)
Mesenteric ischemia
Change in bowel habit + Left iliac fossa pain + Infection (pyrexia)
Diverticulitis
Milk production outside lactation is called? and its causes
Galatorrhea
nipple stimulation and prolactinoma of anterior pituitary
Cause of acute mastitis
S.. Aureus
treat with Flucoxacillin
Periductal mastitis is common in
Smokers
* blocked duct through keratin
may present with nipple traction
Green-brown nipple discharge
mammary duct ectasia
inflammation of the duct, subareolar ducts inflammation, post-menopausal women, breast mass
Related to trauma, calcification on mammogram
Fat necrosis
fibrosis of connective tissue and hypertrophy of lobules and ducts; some carry increased risk of carcinoma (invasive), cysts and apocrine metaplasia, worse pain before period
Fibrocystic disease
bloody discharge
intraductal papilloma
single duct only
Treat- Microdiscectomy
Fibrous tissue and gland, benign, premenopausal, mobile, well circumscribed, marble like and estrogen sensitive
Fibroadenoma
> 3cm exicise surgically
Mastectomy if large lesion
Phyllodes tumour
Fibroadenoma like tumor, leaf like projections and can be malignant
smooth discrete lump; fluctuant, small increased risk of cancer
breast cyst- aspirated
risk factors of breast cancer
Female, age, early menarche, late menopause, obesity,, atypical hyperplasia and 1st degree relative
What is the functional unit of breast
Terminal duct lobule
DCIS
malignant + basement membrane
Epidermis + malignant in the duct
Paget’s
Malignant lobule
LCIS
Invasion into connective tissue
Invasive lobular cancer
Comedo type DCIS
High grade cells with necrosis and dystrophic calcification in center of ducts
DCIS + nipple involvement + erythema
Pagets
Most common type of breast cancer
Invasive ductal carcinoma
Breast is erythematous, mastitis, no resolve with ABx
inflammatory breast cancer
BRCA1 is related to
medullary carcinoma
Do a sentinel when the axilla cannot be palpated and positive USS
That means no nodes are present and exision of one node can tell us if clearance is required
Poor prognosis of breast cancer
triple negative
BRCA1 and 2 are Inherited
Autosomal dominant
BRCA1 is related to what other cancer
ovarian
BRCA 2
related to male breast cancer
DCIS >4cm
Mastectomy
DCIS <4 cm
wide local excision
NHS breast screening
50-70 every three years
Clinically palpable axillary nodes
Axillary node clearance is indicated
SE of Axillary node clearance
Lymphedema and functional arm impairment
Radiotherapy indications
whole breast - Wide local exicision
T3/T4 or those with 4 or more positive nodes - Mastectomy
Premenopausal ER+
tamoxifen
Post-menopausal ER+
Anastrazole
SE of Tamoxifen
Endometrial cancer; VTE and menopausal sxs
Biological therapy
Trastuzumab or Herceptin
HER2 positive
CI heart disease
Chemotherapy
Axillary node disease FEC-D
AAA screening
USS in all men 65 year old
Risks of AAA
Smoking, male, increased age, hypertension, FH, CAD, MArfans,
Infrarenal aortic diameter of more than 3 Cm
Usually arises below the renal arteries and above the bifurcation into iliacs
Classic presentation - Severe abdominal pain radiating to back and presence of a pulsating mass
AAA
Diagnosis
USS- large cystic lesion
Gold standard is CT or MRI
Management of AAA
asymptomatic - Pharma and lifestyle - Statin, antiplatelet, antihypertensive and beta blocker
If asx and >5.5 cm and 0.5 cm per year expansion - surgery
Symptomatic: Surgery
Surgery type in AAA
EVAR has decreased perioperative mortality
NO decrease in mortality by 5 years due to fatal endograft failure
EVAR requires lifeling surviellance
Open: durable for younger patients
Complication of AAA EVAR graft
Bloody stools relating to ischemic colitis
Endo-leak
<3 cm
3 to 4.4
4.5 to 5.4
>5.5
<3 cm = Normal
3 to 4.4 = small - rescan 12 months
4.5 to 5.4 = Medium - rescan every 3 months
>5.5 - refer 2 weeks to intervention
Emergency AAA repair
Oxygen, Keep SBP <100, MHP, Cef + metronidazole; Dacron graft
Tear of the intima, allowing blood through the media of the aortic wall
Aortic dissection
Most common cause of dissection
Hypertension
Sharp pain, sudden onset, radiating to back, tearing, pulse deficit- weak carotid, brachial or femoral, variation in systolic BP, ST elevation in inferior leads
Aortic dissection
Type A dissection
AA +/- DA
Type B dissection
distal to subclavian artery in descending aorta
Type A leads to complications such as
heart failure, aortic valve insufficiency, cardiac tamponade and shock
Diagnosis gold standard of dissection
CT angiogram of chest, abdomen, pelvis
TOE- oesophageal unstable or TTE
AA + DA
Type 1 debakey
AA only
Type 2
DA only
type 3
Most common cause of death in aortic dissection
pericardial tamponade
others: renal artery stenosis
Type A
Surgical + BP management
Type B
Conservative, IV labetalol
backward tear complications in dissection
AR, MI inferior wall
Forward tear complication in dissection
Unequal pulses and stroke + renal failure
Poor blood supply to skin + PAD causes
Arterial ulcers
Pooling of blood and waste products in the skin secondary to venous deficiency such as varicose and phlebitis
Venous ulcers
Combination of ulcers
Mixed
Ulcer with absent pulse, pallor, small, regular, grey colour, not bleeding, more painful, pain with elevation and improved by hanging
Arterial ulcer
An ulcer which is edematous, flushed, hyperpigmented, varicose eczema, larger, irregular border, likely to bleed and relieves with elevation and worse on hanging
Venous ulcer
Brown pigmentation, lipodermatosclerosis, eczema, above ankle, painless, DVT, varicose, medial malleolus, hemosiderin
Venous
management
1st line 4 layer compression bandage
Squamous cell carcinoma, occuring at chronic inflammation sites such as burns or osteomyelitis
Marjoin’s ulcer
Pyoderma gangrenosum
IBD, RA, stoma sites pustules that can ulcerate
Pentoxyfylline improves
VV: microcirculatory blood flow and improves healing rates
Surgical management of varicose veins
Compression stocking
Pentoxifylline
ENdothermal ablation (radiofrequency) endovenous laser
foam sclerotherapy
Others: trendelberg (sapgenofemoral), SSV (popliteal)
Investigation of Varicose veins
Duplex uss
Origin of CVA and TIA
internal carotid A
neurological symptoms related to Internal carotid
Amaurosis fugax- central retinal artery
Hemianopia
internal capsular stroke
Diagnosis carotid disease
All patients with TIA/CVA within last 6 months - Duplex
2nd line MRA or CTA - inconclusive duplex
Management of carotid A disease
Antiplatelet such as aspirin, dipyridamole, smoking cessation, BP and diabetes
Statin for cholestrol
Acute thrombolysis in CT proven ischemia
ABCD2 risk score in TIA
> 50 and symptomatic
>70% stenosis
Complication of CEA
hypoglossal nerve and glossopharyngeal nerve
great auricular - numb ear lobe
hoarse voice - recurrent laryngeal
Stenting can be considered
young patients with carotid disease
Aching, burning legs, can walk predictable distances and relived with rest
Intermittent claudication
investigation of Intermittent claudication
Duplex USS, ABPI
Rest pain in foor >2 weeks, ulcer or gangrene
pain eases on hanging legs
ABPI <0.5
Critical limb ischemia
6 Ps: pale, pulseless, paralysed, paraesthetic and cold
Acute limb ischemia
Thrombus
pre-existing claudication and deterioration
Emboli
no claudication, AF, MI, normal pulses in contralateral limb
ABPI scores
1 = normal
0.6 to 0.9 = claudication
0.3 to 0.6 = rest pain
<0.3 = impending
management of PAD
Smoking cessation, statin 80mg, Clopidogrel 1st line
Severe pad and critical limb ischemia
Angioplasty, stenting and bypass
Drugs used PAD
Naftridrifuryl oxlate and cilostazol
Doppler
Normal is triphasic
Mild stenosis is biphasic
Severe stenosis is monophasic
ABPI >1.4
Calcification due to DM and chronic renal failure
Endovascular treatment
p/c transluminal angioplasty + stenting
Diagnosis of thrombosis acute limb
angiography
Treatment of thrombosis and embolus acute limb
Thrombolysis and bypass- thrombus
Embolectomy + warfarin - emboli- Fogarty catheter