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Year 3 > Hematology > Flashcards

Hematology Flashcards

1
Q

DIC in sepsis

A

Deranged coagulation

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2
Q

Cryoprecipitate constitution

A

factor 8 + fibrinogen + vWF + factor 13

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3
Q

Hemoarthroses, hematomas, prolonged bleeding; prolonged APTT

A

Hemophilia Factor 8 and 9

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4
Q

Factor 5 leidin

A

Activated protein C resistance

Inherited thrombophilia commonest

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5
Q

Tear drop poikilocytes

A

Myelofibrosis

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6
Q

Pencil piokilocytes

A

iron deficiency anemia

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7
Q

Howell-Jolly Bodies and Siderocytes

A

hyposplenism

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8
Q

Schistocytes

A

Hemolysis Such as Hereditary spherocytosis

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9
Q

Spherocytes

A

Hereditary spherocytosis or AIHA

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10
Q

CML treatment

A

Imatinib- TK inhibitor

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11
Q

Ritcher’s transformation

A

B symptoms - fever, weight loss, nigh sweats; CLL to large cell lymphoma; diagnose by biopsy of lymph node

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12
Q

DIC on coagulation test

A

Low platelet
Low fibrinogen
Increased PT and APTT
Increased FDPs

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13
Q

VTE risk

A

Factor 5 Leiden or Protein C resistance

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14
Q

Bleeding disorder that is inherited autosomal

A

VWF

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15
Q

Anti Tb medication, alcohol, myelodysplasia, lead and microcytosis are related to

A

Sideroblastic anemia

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16
Q

Basophilic stippling of cells - RBC

A

Sideroblastic Anemia

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17
Q

Most common type of leukaemia in adults

A

Chronic Lymphocytic Leukemia

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18
Q

Blood film of CLL

A

Smear cells aka Smudge cells

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19
Q

Petichae, purpura, epistaxis, in old females

A

ITP

20
Q

1st line management of ITP

A

Prednisolone

21
Q

Band cells

A

CML

22
Q

BLAST CELLS

A

AML

23
Q

Burkitt’s Lymphoma mutation

A

C-MYC gene translocation

24
Q

Clotting in Hemophilia - PT, APTT and Bleeding time

A

APTT increased
PT normal
BT normal

25
Q

Coagulation test in VWD

A

APTT raised
PT normal
Bleeding time raised

26
Q

Vitamin K deficiency coagulation

A

APTT increased
PT increased
Bleeding time normal

27
Q

CLL to High grade non-Hodgkin lymphoma is called

A

Ritcher’s transformation

28
Q

Tumour lysis syndrome

A

Lymphoma + Chemo + uremia, Hyperkalemia, hyperphosphatemia and hypocalcemia and increased creatinine/ Arrhythmia or seizure

29
Q

Hypercalcemia; Pancytopenia and AKI, Proteinuria

A

Multiple myeloma

30
Q

Myelodysplasia transforms into?

A

Acute myeloid Leukemia

31
Q

Smudge cells or Smear cells

A

CLL

32
Q

Pseudo-pelger Huet cells

A

CML

33
Q

Back pain, >60, leukopenia and Hypercalcemia. choice of investigation

A

Protein electrophoresis and Bence-Jones protein testing

34
Q

A painful maculopapular rash in a allogenic host

A

Graft vs Host disease

35
Q

Isolated Low platelets

A

Commonly ITP

36
Q

Anemia, Fever, purpura and cerebral dysfunction; a hematological disorder, low platelets, microangiopathic anemia, AKI

A

TTP

37
Q

IgA deficiency increases the risk of blood transfusion reaction

A

Anaphylactic

38
Q

EMA binding test is used for

A

Hereditary spherocytosis

39
Q

Basophilic stippling and Cabot rings

A

Lead poisoning

40
Q

Rouleaux formation

A

Myeloma

41
Q

Lymphoma, Raynauld’s, worse on cold symptoms and new macrocytic anemia

A

AIHA

42
Q

Ovarian cancer spreads

A

Locally

43
Q

Myeloma - Calcium, Phosphate and ALP

A

High calcium
Normal or high phosphate
NOrmal ALP

44
Q

Haemarthrosis is a sign of what hemotological disease

A

Hemophilia A

45
Q

CLL is associated with what type of haemolytic anemia

A

Warm autoimmune anemia

46
Q

COLD AIHA

A

Lymphoma, EBV, mycoplasma

Year 3 (11 decks)

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