Hematology

Question 1

DIC in sepsis

Answer 1

Deranged coagulation

Question 2

Cryoprecipitate constitution

Answer 2

factor 8 + fibrinogen + vWF + factor 13

Question 3

Hemoarthroses, hematomas, prolonged bleeding; prolonged APTT

Answer 3

Hemophilia Factor 8 and 9

Question 4

Factor 5 leidin

Answer 4

Activated protein C resistance

Inherited thrombophilia commonest

Question 5

Tear drop poikilocytes

Answer 5

Myelofibrosis

Question 6

Pencil piokilocytes

Answer 6

iron deficiency anemia

Question 7

Howell-Jolly Bodies and Siderocytes

Answer 7

hyposplenism

Question 8

Schistocytes

Answer 8

Hemolysis Such as Hereditary spherocytosis

Question 9

Spherocytes

Answer 9

Hereditary spherocytosis or AIHA

Question 10

CML treatment

Answer 10

Imatinib- TK inhibitor

Question 11

Ritcher’s transformation

Answer 11

B symptoms - fever, weight loss, nigh sweats; CLL to large cell lymphoma; diagnose by biopsy of lymph node

Question 12

DIC on coagulation test

Answer 12

Low platelet
Low fibrinogen
Increased PT and APTT
Increased FDPs

Question 13

VTE risk

Answer 13

Factor 5 Leiden or Protein C resistance

Question 14

Bleeding disorder that is inherited autosomal

Answer 14

VWF

Question 15

Anti Tb medication, alcohol, myelodysplasia, lead and microcytosis are related to

Answer 15

Sideroblastic anemia

Question 16

Basophilic stippling of cells - RBC

Answer 16

Sideroblastic Anemia

Question 17

Most common type of leukaemia in adults

Answer 17

Chronic Lymphocytic Leukemia

Question 18

Blood film of CLL

Answer 18

Smear cells aka Smudge cells

Question 19

Petichae, purpura, epistaxis, in old females

Answer 19

ITP

Question 20

1st line management of ITP

Answer 20

Prednisolone

Question 21

Band cells

Answer 21

CML

Question 22

BLAST CELLS

Answer 22

AML

Question 23

Burkitt’s Lymphoma mutation

Answer 23

C-MYC gene translocation

Question 24

Clotting in Hemophilia - PT, APTT and Bleeding time

Answer 24

APTT increased
PT normal
BT normal

Question 25

Coagulation test in VWD

Answer 25

APTT raised
PT normal
Bleeding time raised

Question 26

Vitamin K deficiency coagulation

Answer 26

APTT increased
PT increased
Bleeding time normal

Question 27

CLL to High grade non-Hodgkin lymphoma is called

Answer 27

Ritcher’s transformation

Question 28

Tumour lysis syndrome

Answer 28

Lymphoma + Chemo + uremia, Hyperkalemia, hyperphosphatemia and hypocalcemia and increased creatinine/ Arrhythmia or seizure

Question 29

Hypercalcemia; Pancytopenia and AKI, Proteinuria

Answer 29

Multiple myeloma

Question 30

Myelodysplasia transforms into?

Answer 30

Acute myeloid Leukemia

Question 31

Smudge cells or Smear cells

Answer 31

CLL

Question 32

Pseudo-pelger Huet cells

Answer 32

CML

Question 33

Back pain, >60, leukopenia and Hypercalcemia. choice of investigation

Answer 33

Protein electrophoresis and Bence-Jones protein testing

Question 34

A painful maculopapular rash in a allogenic host

Answer 34

Graft vs Host disease

Question 35

Isolated Low platelets

Answer 35

Commonly ITP

Question 36

Anemia, Fever, purpura and cerebral dysfunction; a hematological disorder, low platelets, microangiopathic anemia, AKI

Answer 36

TTP

Question 37

IgA deficiency increases the risk of blood transfusion reaction

Answer 37

Anaphylactic

Question 38

EMA binding test is used for

Answer 38

Hereditary spherocytosis

Question 39

Basophilic stippling and Cabot rings

Answer 39

Lead poisoning

Question 40

Rouleaux formation

Answer 40

Myeloma

Question 41

Lymphoma, Raynauld’s, worse on cold symptoms and new macrocytic anemia

Answer 41

AIHA

Question 42

Ovarian cancer spreads

Answer 42

Locally

Question 43

Myeloma - Calcium, Phosphate and ALP

Answer 43

High calcium
Normal or high phosphate
NOrmal ALP

Question 44

Haemarthrosis is a sign of what hemotological disease

Answer 44

Hemophilia A

Question 45

CLL is associated with what type of haemolytic anemia

Answer 45

Warm autoimmune anemia

Question 46

COLD AIHA

Answer 46

Lymphoma, EBV, mycoplasma