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Immunology - Serology > Surface Markers on T and B Cells > Flashcards

Surface Markers on T and B Cells Flashcards

1
Q

What does the accronym “CD” stand for?

A

Cluster of Designation

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2
Q

What are the cell types of the CD2 antigen?

A

Thymocytes
T cells
NK cells

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3
Q

What are the cell types of the CD3 antigen?

A

Thymocytes
T cells
T cell Receptor

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4
Q

What are the cell types of the CD4 antigen?

A

Helper T cells

Monocytes and Macrophages

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5
Q

What are the cell types of the CD5 antigen?

A

Mature T cells
Thymocytes
Subset of B cells (B1)

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6
Q

What are the cell types of the CD8 antigen?

A

Thymocyte subsets

Cytotoxic T cells

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7
Q

What are the cell types of the CD10 antigen?

A

B and T cell precursors

Bone marrow stromal cells

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8
Q

What are the cell types of the CD16 antigen?

A

Macrophages
NK cells
Neutrophils

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9
Q

What are the cell types of the CD19 antigen?

A

B cells

Follicular Dendritic cells

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10
Q

What are the cell types of the CD21 antigen?

A

B cells
Follicular Dendritic cells
Subset of immature Thymocyte

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11
Q

What are the cell types of the CD23 antigen?

A

B cells
Monocytes
Follicular Dendritic cells

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12
Q

What are the cell types of the CD25 antigen?

A

Activated T and B cells

Monocytes

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13
Q

What are the cell types of the CD44 antigen?

A

Most leukocytes

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14
Q

What are the cell types of the CD45R antigen?

A

Different forms on all hematopoietic cells

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15
Q

What are the cell types of the CD56 antigen?

A

NK cells

Subsets of T cells

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16
Q

What are the cell types of the CD94 antigen?

A

NK cells

Subset of T cells

17
Q

What is the function of the CD2 antigen?

A

Involved in T cell activiation

18
Q

It is associated with T CELL ANTIGEN RECEPTOR and has a role in TCR transduction

A

CD3

19
Q

Co-receptor for MHC Class II and a receptor for HIV

A

CD4

20
Q

Positive or negative modulation of T and B cell receptor signaling

A

CD5

21
Q

Co-receptor for MHC Class I

A

CD8

22
Q

A protease

Marker for pre-B CALLA (Common Acute Lymphoblastic Leukemia Antigen)

A

CD10

23
Q

Has Low affinity Fc receptor, mediates phagocytosis and ADCC

A

CD16

24
Q

Part of the B cell co-receptor

Signal transduction molecule that regulates B cell development adn activation

A

CD19

25
Q

Receptor for Complement component C3d

Part of B cell co-recetor with CD 19

A

CD21

26
Q

Regulation of IgE synthesis

Triggers releaseof GM-CSF from monocytes

A

CD23

27
Q

Receptor for IL-2

A

CD25

28
Q

Adhesion molecule mediating homing to peripheral lymphoid organs

A

CD44

29
Q

Essential in T and B cell antigen-stimulation activiation

A

CD45R

30
Q

Subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity

A

CD94

31
Q

What is the function of the CD56 antigen?

A

Unknown

Immunology - Serology (7 decks)

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