Surface Markers on T and B Cells Flashcards
What does the accronym “CD” stand for?
Cluster of Designation
What are the cell types of the CD2 antigen?
Thymocytes
T cells
NK cells
What are the cell types of the CD3 antigen?
Thymocytes
T cells
T cell Receptor
What are the cell types of the CD4 antigen?
Helper T cells
Monocytes and Macrophages
What are the cell types of the CD5 antigen?
Mature T cells
Thymocytes
Subset of B cells (B1)
What are the cell types of the CD8 antigen?
Thymocyte subsets
Cytotoxic T cells
What are the cell types of the CD10 antigen?
B and T cell precursors
Bone marrow stromal cells
What are the cell types of the CD16 antigen?
Macrophages
NK cells
Neutrophils
What are the cell types of the CD19 antigen?
B cells
Follicular Dendritic cells
What are the cell types of the CD21 antigen?
B cells
Follicular Dendritic cells
Subset of immature Thymocyte
What are the cell types of the CD23 antigen?
B cells
Monocytes
Follicular Dendritic cells
What are the cell types of the CD25 antigen?
Activated T and B cells
Monocytes
What are the cell types of the CD44 antigen?
Most leukocytes
What are the cell types of the CD45R antigen?
Different forms on all hematopoietic cells
What are the cell types of the CD56 antigen?
NK cells
Subsets of T cells
What are the cell types of the CD94 antigen?
NK cells
Subset of T cells
What is the function of the CD2 antigen?
Involved in T cell activiation
It is associated with T CELL ANTIGEN RECEPTOR and has a role in TCR transduction
CD3
Co-receptor for MHC Class II and a receptor for HIV
CD4
Positive or negative modulation of T and B cell receptor signaling
CD5
Co-receptor for MHC Class I
CD8
A protease
Marker for pre-B CALLA (Common Acute Lymphoblastic Leukemia Antigen)
CD10
Has Low affinity Fc receptor, mediates phagocytosis and ADCC
CD16
Part of the B cell co-receptor
Signal transduction molecule that regulates B cell development adn activation
CD19
Receptor for Complement component C3d
Part of B cell co-recetor with CD 19
CD21
Regulation of IgE synthesis
Triggers releaseof GM-CSF from monocytes
CD23
Receptor for IL-2
CD25
Adhesion molecule mediating homing to peripheral lymphoid organs
CD44
Essential in T and B cell antigen-stimulation activiation
CD45R
Subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity
CD94
What is the function of the CD56 antigen?
Unknown