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Immunology - Serology > Ch. 26 - Hypersensitivity Reactions (Turgeon): Table 26-1,2 (For Midterm) > Flashcards

Ch. 26 - Hypersensitivity Reactions (Turgeon): Table 26-1,2 (For Midterm) Flashcards

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1
Q

What is the type of reaction of hypersensitivity reaction type I?

A

Anaphylactic

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2
Q

What is the type of reaction of hypersensitivity reaction type II?

A

Cytotoxic

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3
Q

What is the type of reaction of hypersensitivity reaction type III?

A

Immune Complex

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4
Q

What is the type of reaction of hypersensitivity reaction type IV?

A

T cell-dependent

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5
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type I?

A

IgE

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6
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type II?

A

IgG, possibly other immunoglobulins

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7
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type III?

A

Antigen-antibody complexes (IgG, IgM)

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8
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type IV?

A

None

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9
Q

Is there a complement involved in the hypersensitivity reaction type I?

A

No

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10
Q

Is there a complement involved in the hypersensitivity reaction type II?

A

Yes

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11
Q

Is there a complement involved in the hypersensitivity reaction type III?

A

Yes

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12
Q

Is there a complement involved in the hypersensitivity reaction type IV?

A

No

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13
Q

These types of hypersensitivity reactions include reactions with antibodies

A

Hypersensitivity reaction type I - III

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14
Q

This type of hypersensitivity reaction is T-cell mediated.

A

Hypersensitivity reaction type IV

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15
Q

Complements are involved in these types of hypersensitivity reactions.

A

Hypersensitivity reaction type II and III

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16
Q

Complements are not involved in these types of hypersensitivity reactions.

A

Hypersensitivity reaction type I and IV

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17
Q

What are the cells involved in the hypersensitivity reaction type I?

A

Mast cells
Basophils
Granules (Histamines)

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18
Q

What are the cells involved in the hypersensitivity reaction type II?

A

Effector cells (macrophages, polymorphonuclear leukocytes)

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19
Q

What are the cells involved in the hypersensitivity reaction type III?

A

Macrophages

Mast cells

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20
Q

What are the cells involved in the hypersensitivity reaction type IV?

A

Antigen-specific T cells

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21
Q

This type of hypersensitivity reaction involves the basophils and granules such as histamine.

A

Hypersensitivity reaction type I

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22
Q

This type of hypersensitivity reaction involves effector cells such as macrophages and polymorphonuclear luekocytes.

A

Hypersensitivity reaction type II

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23
Q

This type of hypersensitivity reaction involves macrophages and mast cells.

A

Hypersensitivity reaction type III

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24
Q

This type of hypersensitivity reaction involves Antigen specific T cells.

A

Hypersensitivity reaction type IV

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25
These types of hypersensitivity reaction involves the mast cells.
Hypersensitivity reaction type I and III
26
These types of hypersensitivity reaction involves the macrophages.
Hypersensitivity reaction type II and III
27
Are there cytokines involved in the hypersensitivity reaction type I?
Yes
28
Are there cytokines involved in the hypersensitivity reaction type II?
No
29
Are there cytokines involved in the hypersensitivity reaction type III?
Yes
30
Are there cytokines involved in the hypersensitivity reaction type IV?
Yes (T cell cytokines)
31
This is the only type of hypersensitivity reaction that does not have cytokine involvement.
Hypersensitivity reaction type II
32
The cytokines involved in this type of hypersensitivity reaction is the T cell cytokines.
Hypersensitivity reaction type IV
33
How is the hypersensitivity reaction type I mediated? (Comparative description)
Antibody mediated, immediate
34
How is the hypersensitivity reaction type II mediated? (Comparative description)
Antibody dependent | Complement or cell mediated
35
How is the hypersensitivity reaction type III mediated? (Comparative description)
Immune complex mediated (Immune complex disease)
36
How is the hypersensitivity reaction type IV mediated? (Comparative description)
T cell mediated, delayed type
37
This type of hypersensitivity reaction is antibody mediated.
Hypersensitivity reaction type I
38
This type of hypersensitivity reaction is complement or cell mediated.
Hypersensitivity reaction type II
39
This type of hypersensitivity reaction is immune complex mediated.
Hypersensitivity reaction type III
40
This type of hypersensitivity reaction is T cell mediated
Hypersensitivity reaction type IV
41
What is the mechanism of tissue injury in a hypersensitivity reaction type I?
Allergic and anaphylactic reactions
42
What is the mechanism of tissue injury in a hypersensitivity reaction type II?
Target cell lysis | Cell-mediated cytotoxicity
43
What is the mechanism of tissue injury in a hypersensitivity reaction type III?
Immune complex deposition | Inflammation
44
What is the mechanism of tissue injury in a hypersensitivity reaction type IV?
Inflammation | Cellular infiltration
45
The mechanism of tissue injury in this type of hypersensitivity reaction is allergic and anaphylactic reactions.
Hypersensitivity reaction type I
46
The mechanism of tissue injury in this type of hypersensitivity reaction is target cell lysis and cell-mediated cytotoxicity.
Hypersensitivity reaction type II
47
The mechanism of tissue injury in this type of hypersensitivity reaction is immune complex deposition inflammation.
Hypersensitivity reaction type III
48
The mechanism of tissue injury in this type of hypersensitivity reaction is inflammation cellular infiltration.
Hypersensitivity reaction type IV
49
The mechanism of tissue injury of these types of hypersensitivity reaction involves inflammation.
Hypersensitivity reaction type III and IV
50
Give examples of hypersensitivity reaction type I.
Anaphylaxis Hay fever Asthma Food allergy
51
Give examples of hypersensitivity reaction type II.
Transfusion reactions Hemolytic disease of newborn Thrombocytopenia
52
Give examples of hypersensitivity reaction type III.
Arthus reaction Serum sickness Systemic lupus erythematosus
53
Give examples of hypersensitivity reaction type IV.
Allergy or infection | Contact dermatitis
54
Examples of this type of hypersensitivity reaction are anaphylaxis, hay fever, asthma, and food allergy.
Hypersensitivity reaction type I
55
Examples of this type of hypersensitivity reaction are transfusion reactions, hemolytic disease of newborn and thrombocytopenia.
Hypersensitivity reaction type II
56
Examples of this type of hypersensitivity reaction are arthus reaction, serum sickness and systemic lupus erythematosus
Hypersensitivity reaction type III
57
Examples of this type of hypersensitivity reaction are llergy or infection and contact dermatitis
Hypersensitivity reaction type IV
58
Give some mediators of anaphylaxis.
``` Histamines Leukotrienes Basophil kallikrein Serotonin Platelet-activating factor Eosinophil chemotactic factor of anaphylaxis Prostaglandins ```
59
The primary action of this mediator of anaphylaxis is to increase vascular permeability; promotes contraction of smooth muscle.
Histamines
60
The primary action of this mediator of anaphylaxis is to alter bronchial smooth muscle and enhance effects of histamine on target organs.
Leukotrienes
61
The primary action of this mediator of anaphylaxis is to generates kinins.
Basophil kallikrein
62
The primary action of this mediator of anaphylaxis is to contract smooth muscle.
Serotonin
63
The primary action of this mediator of anaphylaxis is to enhance the release of histamine and serotonin from platelets that affect smooth muscle tone and vascular permeability.
Platelet-activating factor
64
The primary action of this mediator of anaphylaxis is to attract eosinophils to area of activity; these cells release secondary mediators that may limit the effects of primary mediators.
Eosinophil | chemotactic factor of anaphylaxis
65
The primary action of this mediator of anaphylaxis affects smooth muscle tone and vascular permeability.
Prostaglandins

Immunology - Serology (7 decks)

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