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Immunology - Serology > Ch. 26 - Hypersensitivity Reactions (Turgeon): Table 26-1,2 (For Midterm) > Flashcards

Ch. 26 - Hypersensitivity Reactions (Turgeon): Table 26-1,2 (For Midterm) Flashcards

1
Q

What is the type of reaction of hypersensitivity reaction type I?

A

Anaphylactic

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2
Q

What is the type of reaction of hypersensitivity reaction type II?

A

Cytotoxic

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3
Q

What is the type of reaction of hypersensitivity reaction type III?

A

Immune Complex

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4
Q

What is the type of reaction of hypersensitivity reaction type IV?

A

T cell-dependent

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5
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type I?

A

IgE

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6
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type II?

A

IgG, possibly other immunoglobulins

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7
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type III?

A

Antigen-antibody complexes (IgG, IgM)

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8
Q

What is the immunnoglobulin involved in the hypersensitivity reaction type IV?

A

None

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9
Q

Is there a complement involved in the hypersensitivity reaction type I?

A

No

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10
Q

Is there a complement involved in the hypersensitivity reaction type II?

A

Yes

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11
Q

Is there a complement involved in the hypersensitivity reaction type III?

A

Yes

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12
Q

Is there a complement involved in the hypersensitivity reaction type IV?

A

No

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13
Q

These types of hypersensitivity reactions include reactions with antibodies

A

Hypersensitivity reaction type I - III

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14
Q

This type of hypersensitivity reaction is T-cell mediated.

A

Hypersensitivity reaction type IV

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15
Q

Complements are involved in these types of hypersensitivity reactions.

A

Hypersensitivity reaction type II and III

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16
Q

Complements are not involved in these types of hypersensitivity reactions.

A

Hypersensitivity reaction type I and IV

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17
Q

What are the cells involved in the hypersensitivity reaction type I?

A

Mast cells
Basophils
Granules (Histamines)

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18
Q

What are the cells involved in the hypersensitivity reaction type II?

A

Effector cells (macrophages, polymorphonuclear leukocytes)

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19
Q

What are the cells involved in the hypersensitivity reaction type III?

A

Macrophages

Mast cells

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20
Q

What are the cells involved in the hypersensitivity reaction type IV?

A

Antigen-specific T cells

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21
Q

This type of hypersensitivity reaction involves the basophils and granules such as histamine.

A

Hypersensitivity reaction type I

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22
Q

This type of hypersensitivity reaction involves effector cells such as macrophages and polymorphonuclear luekocytes.

A

Hypersensitivity reaction type II

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23
Q

This type of hypersensitivity reaction involves macrophages and mast cells.

A

Hypersensitivity reaction type III

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24
Q

This type of hypersensitivity reaction involves Antigen specific T cells.

A

Hypersensitivity reaction type IV

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25
Q

These types of hypersensitivity reaction involves the mast cells.

A

Hypersensitivity reaction type I and III

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26
Q

These types of hypersensitivity reaction involves the macrophages.

A

Hypersensitivity reaction type II and III

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27
Q

Are there cytokines involved in the hypersensitivity reaction type I?

28
Q

Are there cytokines involved in the hypersensitivity reaction type II?

29
Q

Are there cytokines involved in the hypersensitivity reaction type III?

30
Q

Are there cytokines involved in the hypersensitivity reaction type IV?

A

Yes (T cell cytokines)

31
Q

This is the only type of hypersensitivity reaction that does not have cytokine involvement.

A

Hypersensitivity reaction type II

32
Q

The cytokines involved in this type of hypersensitivity reaction is the T cell cytokines.

A

Hypersensitivity reaction type IV

33
Q

How is the hypersensitivity reaction type I mediated? (Comparative description)

A

Antibody mediated, immediate

34
Q

How is the hypersensitivity reaction type II mediated? (Comparative description)

A

Antibody dependent

Complement or cell mediated

35
Q

How is the hypersensitivity reaction type III mediated? (Comparative description)

A

Immune complex mediated (Immune complex disease)

36
Q

How is the hypersensitivity reaction type IV mediated? (Comparative description)

A

T cell mediated, delayed type

37
Q

This type of hypersensitivity reaction is antibody mediated.

A

Hypersensitivity reaction type I

38
Q

This type of hypersensitivity reaction is complement or cell mediated.

A

Hypersensitivity reaction type II

39
Q

This type of hypersensitivity reaction is immune complex mediated.

A

Hypersensitivity reaction type III

40
Q

This type of hypersensitivity reaction is T cell mediated

A

Hypersensitivity reaction type IV

41
Q

What is the mechanism of tissue injury in a hypersensitivity reaction type I?

A

Allergic and anaphylactic reactions

42
Q

What is the mechanism of tissue injury in a hypersensitivity reaction type II?

A

Target cell lysis

Cell-mediated cytotoxicity

43
Q

What is the mechanism of tissue injury in a hypersensitivity reaction type III?

A

Immune complex deposition

Inflammation

44
Q

What is the mechanism of tissue injury in a hypersensitivity reaction type IV?

A

Inflammation

Cellular infiltration

45
Q

The mechanism of tissue injury in this type of hypersensitivity reaction is allergic and anaphylactic reactions.

A

Hypersensitivity reaction type I

46
Q

The mechanism of tissue injury in this type of hypersensitivity reaction is target cell lysis and cell-mediated cytotoxicity.

A

Hypersensitivity reaction type II

47
Q

The mechanism of tissue injury in this type of hypersensitivity reaction is immune complex deposition
inflammation.

A

Hypersensitivity reaction type III

48
Q

The mechanism of tissue injury in this type of hypersensitivity reaction is inflammation
cellular infiltration.

A

Hypersensitivity reaction type IV

49
Q

The mechanism of tissue injury of these types of hypersensitivity reaction involves inflammation.

A

Hypersensitivity reaction type III and IV

50
Q

Give examples of hypersensitivity reaction type I.

A

Anaphylaxis
Hay fever
Asthma
Food allergy

51
Q

Give examples of hypersensitivity reaction type II.

A

Transfusion reactions
Hemolytic disease of newborn
Thrombocytopenia

52
Q

Give examples of hypersensitivity reaction type III.

A

Arthus reaction
Serum sickness
Systemic lupus erythematosus

53
Q

Give examples of hypersensitivity reaction type IV.

A

Allergy or infection

Contact dermatitis

54
Q

Examples of this type of hypersensitivity reaction are anaphylaxis, hay fever, asthma, and food allergy.

A

Hypersensitivity reaction type I

55
Q

Examples of this type of hypersensitivity reaction are transfusion reactions, hemolytic disease of newborn and thrombocytopenia.

A

Hypersensitivity reaction type II

56
Q

Examples of this type of hypersensitivity reaction are arthus reaction, serum sickness and systemic lupus erythematosus

A

Hypersensitivity reaction type III

57
Q

Examples of this type of hypersensitivity reaction are llergy or infection and contact dermatitis

A

Hypersensitivity reaction type IV

58
Q

Give some mediators of anaphylaxis.

A 
Histamines
Leukotrienes
Basophil kallikrein
Serotonin
Platelet-activating factor
Eosinophil
   chemotactic factor of anaphylaxis
Prostaglandins
59
Q

The primary action of this mediator of anaphylaxis is to increase vascular permeability; promotes contraction of smooth muscle.

A

Histamines

60
Q

The primary action of this mediator of anaphylaxis is to alter bronchial smooth muscle and enhance effects of histamine on target organs.

A

Leukotrienes

61
Q

The primary action of this mediator of anaphylaxis is to generates kinins.

A

Basophil kallikrein

62
Q

The primary action of this mediator of anaphylaxis is to contract smooth muscle.

63
Q

The primary action of this mediator of anaphylaxis is to enhance the release of histamine and serotonin from platelets that affect smooth muscle tone and vascular permeability.

A

Platelet-activating factor

64
Q

The primary action of this mediator of anaphylaxis is to attract eosinophils to area of activity; these cells release secondary mediators that may limit the effects of primary mediators.

A

Eosinophil

chemotactic factor of anaphylaxis

65
Q

The primary action of this mediator of anaphylaxis affects smooth muscle tone and vascular permeability.

A

Prostaglandins

Immunology - Serology (7 decks)

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