Ch. 2 - for Prelim exam (Table 2-2) Flashcards
What is the MW (molecular weight) of IgM?
900,000 Da
What is the MW (molecular weight) of IgA?
360,000 Da
What is the MW (molecular weight) of IgE?
200,000 Da
What is the MW (molecular weight) of IgG?
160,000 Da
What is the MW (molecular weight) of IgD?
160,000 Da
What is the Sedimentation coefficient of IgM?
19
What is the Sedimentation coefficient of IgA?
11
What is the Sedimentation coefficient of IgE?
8
What is the Sedimentation coefficient of IgG?
7
What is the Sedimentation coefficient of IgD?
7
What is the percent of carbohydrate in IgM, IgE and IgD?
12
What is the percent of carbohydrate in IgA?
7
What is the percent of carbohydrate in IgG?
8
Which among the Ig classes has subclasses? Enumerate their subclasses.
IgG1-4
IgA: alpha 1 & 2
What is the serum concentration of IgG (mg/dL) in adults?
13.5
What is the serum concentration of IgA (mg/dL) in adults?
3.5
What is the serum concentration of IgM (mg/dL) in adults?
1.5
What is the serum concentration of IgE (mg/dL) in adults?
0.05
What is the serum concentration of IgD (mg/dL) in adults?
Trace*
What is the serum half-life of IgG?
23
What is the serum half-life of IgA?
6
What is the serum half-life of IgM?
5
What is the serum half-life of IgD?
3
What is the serum half-life of IgE?
2.5
What Ig has the highest MW?
IgM (900,000 Da)
What Ig has the lowest MW?
IgG & IgD (160,000 Da)
What Ig has the highest Sedimentation coefficient?
IgM (19)
What Ig has the lowest Sedimentation coefficient?
IgG & IgD (7)
What Ig has the highest percent of carbohydrate?
IgM, IgE, and IgD (12)
What Ig has the lowest percent of carbohydrate?
IgA (7)
What Ig has the highest serum concentration (mg/dL) in adults?
IgG (13.5)
What Ig has the lowest serum concentration (mg/dL) in adults?
IgD (Trace)
What Ig has the highest serum half-life?
IgG (23)
What Ig has the lowest serum half-life?
IgE (2.5)