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Biology4351 > super final awfully specific exam questions > Flashcards

super final awfully specific exam questions Flashcards

1
Q

True/False: Agonists possess affinity only

A

FALSE- Antagonists possess affinity only

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2
Q

True/False: The 1st pass effect applies to drugs administered orally

A

TRUE

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3
Q

True/False: The uncharged form of a weak base with a pKa=8.2 would be most abundant at a pH=1.6

A

FALSE- A weak base will dissociate in an acidic solution and the charged form will dominate

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4
Q

True/False: The charged form of a weak acid with a pKa=4.3 would be most abundant at a pH=2.8

A

FALSE- A weak acid will not dissociate in an acidic solution and the uncharged form will dominate

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5
Q

True/False: If drug A is more potent than drug B, then drug B is more efficacious than drug A

A

FALSE

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6
Q

True/False: Pareneteral administration of a drug is the most effect route of administration

A

FALSE

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7
Q

True/False: Pharmocodynamics deals with the effects of a drug on the body

A

TRUE

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8
Q

The liver plays a major role in drug excretion

A

TRUE

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9
Q

Drugs administered IV have 1000% bioavailability

A

TRUE

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10
Q

True/False: Tachycardia can result from the administration of metoprolol because it has β1 affinity

A

FALSE

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11
Q

True/False: Tachycardia can result from the administration of bethanecol because it is a direct-acting muscarinic agonist

A

FALSE

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12
Q

True/False: Tachycardia can result from the administration of neostigmine because it is a muscarinic antagonist

A

FALSE

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13
Q

True/False: Tachycardia can result from the administration of phenylephrine because it increases SVR

A

FALSE

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14
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will stimulate E secretion from the adrenal medulla

A

TRUE

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15
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause diarrhea by directly stimulating β2 receptors

A

FALSE

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16
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will decrease SVR by directly stimulating α1 receptors

A

FALSE

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17
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause spastic skeletal muscle paralysis

A

FALSE

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18
Q

True/False: Epinephrine is a positive chronotrope

A

TRUE

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19
Q

True/False: Epinephrine decreases digestive system activity due to its β2 effect

A

TRUE

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20
Q

True/False: Epinephrine is a positive inotrope

A

TRUE

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21
Q

True/False: Epinephrine is a vasoconstrictor due to its α1 effect

A

TRUE

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22
Q

True/False: Epinephrine is a vasodilator due to its β2 effect

A

TRUE

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23
Q

True/False: Epinephrine is a bronchodilator due to its β2 effect

A

TRUE

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24
Q

True/False: Atropine relaxes skeletal muscle because it is a cholinergic receptor antagonist

A

FALSE

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25
Q

True/False: Atropine is a positive chronotrope because it is an antimuscarinic drug

A

TRUE

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26
Q

True/False: Atropine decreases bronchial mucous secretion by blocking Nn receptors

A

FALSE

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27
Q

True/False: Atropine is a bronchodilator

A

TRUE

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28
Q

True/False: Labetalol causes reflex tachycardia

A

FALSE

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29
Q

True/False: Labetalol is a vasodilator

A

TRUE

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30
Q

True/False: Labetalol can cause orthostatic hypotension by blocking adrenergic receptors

A

TRUE

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31
Q

True/False: Labetalol lowers BP by reducing CO

A

TRUE

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32
Q

True/False: Metoprolol lowers BP by reducing SVR

A

FALSE

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33
Q

True/False: Metoprolol directly reduces CO

A

TRUE

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34
Q

True/False: Metoprolol targets the same receptors as dobutamine

A

TRUE

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35
Q

True/False: Metoprolol causes reflex bradycardia

A

FALSE

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36
Q

True/False: Phenylephrine causes reflex bradycardia because it reduces BP

A

FALSE

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37
Q

True/False: Phenylephrine targets a receptor targeted by NE

A

TRUE

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38
Q

True/False: Phenylephrine directly increases myocardial contractility

A

FALSE

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39
Q

True/False: Phenylephrine is an effective decongestant

A

TRUE

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40
Q

ACE Inhibitors AND/OR Cardioselective beta blockers block AII production

A

ACE INHIBITORS

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41
Q

ACE Inhibitors AND/OR Cardioselective beta blockers lower BP by reducing SVR

A

ACE INHIBITORS

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42
Q

ACE Inhibitors AND/OR Cardioselective beta blockers decrease LV afterload by reducing blood volume

A

NEITHER

43
Q

ACE Inhibitors AND/OR Cardioselective beta blockers can successfully treat CHF

A

BOTH

44
Q

ACE Inhibitors AND/OR Cardioselective beta blockers can cause hypokalemia

A

NEITHER

45
Q

ACE Inhibitors AND/OR Cardioselective beta blockers decrease myocardial workload

A

ACE INHIBITORS

46
Q

ARB’s AND/OR CA++ Channel Blockers are vasodilators

A

BOTH

47
Q

ARB’s AND/OR CA++ Channel Blockers reduce SVR

A

BOTH

48
Q

ARB’s AND/OR CA++ Channel Blockers decrease AII production

A

NEITHER

49
Q

ARB’s AND/OR CA++ Channel Blockers can cause hypokalemia

A

NEITHER

50
Q

ARB’s AND/OR CA++ Channel Blockers are negative chronotropes

A

CA++ CHANNEL BLOCKERS

51
Q

Dobutamine AND/OR Digoxin is useful in the treatment of systolic heart failure

A

BOTH

52
Q

Dobutamine AND/OR Digoxin inhibits the Na/K pump

A

DIGOXIN

53
Q

Dobutamine AND/OR Digoxin is a β1 agonist

A

DOBUTAMINE

54
Q

Dobutamine AND/OR Digoxin is a positive inotrope

A

BOTH

55
Q

HCTZ AND/OR Furosemide reduces preload by reducing SVR

A

NEITHER

56
Q

HCTZ AND/OR Furosemide targets the DCT

A

HCTZ

57
Q

HCTZ AND/OR Furosemide increases Na absorption in the renal tubules

A

NEITHER

58
Q

HCTZ AND/OR Furosemide can cause hypokalemia

A

BOTH

59
Q

True/False: A hypertensive patient would benefit from clonidine because it reduces CO

A

TRUE

60
Q

True/False: A hypertensive patient would benefit from atenolol because it reduces stroke volume

A

TRUE

61
Q

True/False: A hypertensive patient would benefit from Lisinopril because it reduces LV afterload

A

TRUE

62
Q

True/False: A hypertensive patient would benefit from diltiazem because it is a negative inotrope

A

TRUE

63
Q

True/False: A hypertensive patient would benefit from labetalol because it is a vasodilator

A

TRUE

64
Q

True/False: Nitroglycerin reduces myocardial O2 demand

A

TRUE

65
Q

True/False: Isosorbide dintrate reduces adterload by dilating veins

A

FALSE

66
Q

True/False: Aspirin is indicated in patients at risk for DVTs

A

FALSE

67
Q

True/False: Statins reduce hepatic cholesterol synthesis b inhibiting HMG CoA reductase

A

TRUE

68
Q

True/False: Warfarin blocks the synthesis of vitamin K dependent clotting factors

A

TRUE

69
Q

True/False: Heparin enhances ATIII activity

A

TRUE

70
Q

True/False: Thrombolytics promote the conversion of plasminogen to plasmin

A

TRUE

71
Q

True/False: A hypertensive patient would benefit from HCTZ because it is a positive inotrope

A

FALSE

72
Q

True/False: Caffeine is a bronchodilator

A

TRUE

73
Q

True/False: Ethanol is a myocardial depressant

A

TRUE

74
Q

Cocaine AND/OR Nicotine is a CNS depressant

A

NEITHER

75
Q

Cocaine AND/OR Nicotine can increase BP

A

BOTH

76
Q

Cocaine AND/OR Nicotine has therapeutic benefit

A

BOTH

77
Q

Cocaine AND/OR Nicotine is an alpha 2 agonist

A

NEITHER

78
Q

Cocaine AND/OR Nicotine can increase heart rate

A

BOTH

79
Q

Cocaine AND/OR Nicotine binds to receptors found in the autonomic nervous system

A

NICOTINE

80
Q

Cocaine AND/OR Nicotine binds to receptors found in the somatic nervous system

A

NICOTINE

81
Q

Albuterol AND/OR salmeterol is a rapid acting b2 agonist

A

ALBUTEROL

82
Q

Albuterol AND/OR salmeterol is a bronchodilator

A

BOTH

83
Q

Albuterol AND/OR salmeterol is a muscarinic receptor agonist

A

NEITHER

84
Q

Albuterol AND/OR salmeterol is used as a “rescue” agent

A

ALBUTEROL

85
Q

Albuterol AND/OR salmeterol reduces airway wall inflammation

A

NEITHER

86
Q

Fluticasone AND/OR montelukast is a slow-acting bronchodilator

A

NEITHER

87
Q

Fluticasone AND/OR montelukast is used as a “rescue” agent

A

NEITHER

88
Q

Fluticasone AND/OR montelukast is a corticosteroid

A

FLUTICASONE

89
Q

Fluticasone AND/OR montelukast is a leukotriene receptor antagonist

A

MONTELUKAST

90
Q

Fluticasone AND/OR montelukast is an anti-inflammatory

A

BOTH

91
Q

Insulin AND/OR sitagliptin can cause hypoglycemia

A

BOTH

92
Q

Insulin AND/OR sitagliptin is a DPP-4 inhibitor

A

SITAGLIPTIN

93
Q

Insulin AND/OR sitagliptin stimulates insulin secretion

A

SITAGLIPTIN

94
Q

Insulin AND/OR sitagliptin is an insulin analogue

A

NEITHER

95
Q

Insulin AND/OR sitagliptin is useful in the treatment of Type I diabetes

A

INSULIN

96
Q

Exenatide AND/OR metformin stimulates insulin secretion

A

EXENATIDE

97
Q

Exenatide AND/OR metformin can cause hypoglycemia

A

BOTH

98
Q

Exenatide AND/OR metformin increases insulin sensitivity

A

METFORMIN

99
Q

Exenatide AND/OR metformin is useful in the treatment of Type II diabetes

A

BOTH

100
Q

True/False: Morphine causes respiratory depression

A

TRUE

101
Q

True/False: Opiod analgesics are also effective antipyretics

A

FALSE

102
Q

True/False: Acetaminophen is a non-opiod NSAID

A

FALSE

103
Q

True/False: Aspirin’s antiplatelet effects are cause by COX-1 inhibition

A

TRUE

Biology4351 (16 decks)

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