super dick Flashcards
True/False: Agonists possess affinity only
FALSE- Antagonists possess affinity only
True/False: The 1st pass effect applies to drugs administered orally
TRUE
True/False: The uncharged form of a weak base with a pKa=8.2 would be most abundant at a pH=1.6
FALSE- A weak base will dissociate in an acidic solution and the charged form will dominate
True/False: The charged form of a weak acid with a pKa=4.3 would be most abundant at a pH=2.8
FALSE- A weak acid will not dissociate in an acidic solution and the uncharged form will dominate
True/False: If drug A is more potent than drug B, then drug B is more efficacious than drug A
FALSE
True/False: Pareneteral administration of a drug is the most effect route of administration
FALSE
True/False: Pharmocodynamics deals with the effects of a drug on the body
TRUE
The liver plays a major role in drug excretion
TRUE
Drugs administered IV have 1000% bioavailability
TRUE
True/False: Tachycardia can result from the administration of metoprolol because it has β1 affinity
FALSE
True/False: Tachycardia can result from the administration of bethanecol because it is a direct-acting muscarinic agonist
FALSE
True/False: Tachycardia can result from the administration of neostigmine because it is a muscarinic antagonist
FALSE
True/False: Tachycardia can result from the administration of phenylephrine because it increases SVR
FALSE
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will stimulate E secretion from the adrenal medulla
TRUE
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause diarrhea by directly stimulating β2 receptors
FALSE
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will decrease SVR by directly stimulating α1 receptors
FALSE
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause spastic skeletal muscle paralysis
FALSE
True/False: Epinephrine is a positive chronotrope
TRUE
True/False: Epinephrine decreases digestive system activity due to its β2 effect
TRUE
True/False: Epinephrine is a positive inotrope
TRUE
True/False: Epinephrine is a vasoconstrictor due to its α1 effect
TRUE
True/False: Epinephrine is a vasodilator due to its β2 effect
TRUE
True/False: Epinephrine is a bronchodilator due to its β2 effect
TRUE
True/False: Atropine relaxes skeletal muscle because it is a cholinergic receptor antagonist
FALSE
True/False: Atropine is a positive chronotrope because it is an antimuscarinic drug
TRUE
True/False: Atropine decreases bronchial mucous secretion by blocking Nn receptors
FALSE
True/False: Atropine is a bronchodilator
TRUE
True/False: Labetalol causes reflex tachycardia
FALSE
True/False: Labetalol is a vasodilator
TRUE
True/False: Labetalol can cause orthostatic hypotension by blocking adrenergic receptors
TRUE
True/False: Labetalol lowers BP by reducing CO
TRUE
True/False: Metoprolol lowers BP by reducing SVR
FALSE
True/False: Metoprolol directly reduces CO
TRUE
True/False: Metoprolol targets the same receptors as dobutamine
TRUE
True/False: Metoprolol causes reflex bradycardia
FALSE
True/False: Phenylephrine causes reflex bradycardia because it reduces BP
FALSE
True/False: Phenylephrine targets a receptor targeted by NE
TRUE
True/False: Phenylephrine directly increases myocardial contractility
FALSE
True/False: Phenylephrine is an effective decongestant
TRUE
ACE Inhibitors AND/OR Cardioselective beta blockers block AII production
ACE INHIBITORS
ACE Inhibitors AND/OR Cardioselective beta blockers lower BP by reducing SVR
ACE INHIBITORS
ACE Inhibitors AND/OR Cardioselective beta blockers decrease LV afterload by reducing blood volume
NEITHER
ACE Inhibitors AND/OR Cardioselective beta blockers can successfully treat CHF
BOTH
ACE Inhibitors AND/OR Cardioselective beta blockers can cause hypokalemia
NEITHER
ACE Inhibitors AND/OR Cardioselective beta blockers decrease myocardial workload
ACE INHIBITORS
ARB’s AND/OR CA++ Channel Blockers are vasodilators
BOTH
ARB’s AND/OR CA++ Channel Blockers reduce SVR
BOTH
ARB’s AND/OR CA++ Channel Blockers decrease AII production
NEITHER
ARB’s AND/OR CA++ Channel Blockers can cause hypokalemia
NEITHER
ARB’s AND/OR CA++ Channel Blockers are negative chronotropes
CA++ CHANNEL BLOCKERS
Dobutamine AND/OR Digoxin is useful in the treatment of systolic heart failure
BOTH
Dobutamine AND/OR Digoxin inhibits the Na/K pump
DIGOXIN
Dobutamine AND/OR Digoxin is a β1 agonist
DOBUTAMINE
Dobutamine AND/OR Digoxin is a positive inotrope
BOTH
HCTZ AND/OR Furosemide reduces preload by reducing SVR
NEITHER
HCTZ AND/OR Furosemide targets the DCT
HCTZ
HCTZ AND/OR Furosemide increases Na absorption in the renal tubules
NEITHER
HCTZ AND/OR Furosemide can cause hypokalemia
BOTH
True/False: A hypertensive patient would benefit from clonidine because it reduces CO
TRUE
True/False: A hypertensive patient would benefit from atenolol because it reduces stroke volume
TRUE
True/False: A hypertensive patient would benefit from Lisinopril because it reduces LV afterload
TRUE
True/False: A hypertensive patient would benefit from diltiazem because it is a negative inotrope
TRUE
True/False: A hypertensive patient would benefit from labetalol because it is a vasodilator
TRUE
True/False: Nitroglycerin reduces myocardial O2 demand
TRUE
True/False: Isosorbide dintrate reduces adterload by dilating veins
FALSE
True/False: Aspirin is indicated in patients at risk for DVTs
FALSE
True/False: Statins reduce hepatic cholesterol synthesis b inhibiting HMG CoA reductase
TRUE
True/False: Warfarin blocks the synthesis of vitamin K dependent clotting factors
TRUE
True/False: Heparin enhances ATIII activity
TRUE
True/False: Thrombolytics promote the conversion of plasminogen to plasmin
TRUE
True/False: A hypertensive patient would benefit from HCTZ because it is a positive inotrope
FALSE
True/False: Caffeine is a bronchodilator
TRUE
True/False: Ethanol is a myocardial depressant
TRUE
Cocaine AND/OR Nicotine is a CNS depressant
NEITHER
Cocaine AND/OR Nicotine can increase BP
BOTH
Cocaine AND/OR Nicotine has therapeutic benefit
BOTH
Cocaine AND/OR Nicotine is an alpha 2 agonist
NEITHER
Cocaine AND/OR Nicotine can increase heart rate
BOTH
Cocaine AND/OR Nicotine binds to receptors found in the autonomic nervous system
NICOTINE
Cocaine AND/OR Nicotine binds to receptors found in the somatic nervous system
NICOTINE
Albuterol AND/OR salmeterol is a rapid acting b2 agonist
ALBUTEROL
Albuterol AND/OR salmeterol is a bronchodilator
BOTH
Albuterol AND/OR salmeterol is a muscarinic receptor agonist
NEITHER
Albuterol AND/OR salmeterol is used as a “rescue” agent
ALBUTEROL
Albuterol AND/OR salmeterol reduces airway wall inflammation
NEITHER
Fluticasone AND/OR montelukast is a slow-acting bronchodilator
NEITHER
Fluticasone AND/OR montelukast is used as a “rescue” agent
NEITHER
Fluticasone AND/OR montelukast is a corticosteroid
FLUTICASONE
Fluticasone AND/OR montelukast is a leukotriene receptor antagonist
MONTELUKAST
Fluticasone AND/OR montelukast is an anti-inflammatory
BOTH
Insulin AND/OR sitagliptin can cause hypoglycemia
BOTH
Insulin AND/OR sitagliptin is a DPP-4 inhibitor
SITAGLIPTIN
Insulin AND/OR sitagliptin stimulates insulin secretion
SITAGLIPTIN
Insulin AND/OR sitagliptin is an insulin analogue
NEITHER
Insulin AND/OR sitagliptin is useful in the treatment of Type I diabetes
INSULIN
Exenatide AND/OR metformin stimulates insulin secretion
EXENATIDE