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Biology4351 > Awfully Specific Exam 1 Questions > Flashcards

Awfully Specific Exam 1 Questions Flashcards

1
Q

True/False: Agonists possess affinity only

A

FALSE- Antagonists possess affinity only

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2
Q

True/False: The 1st pass effect applies to drugs administered orally

A

TRUE

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3
Q

True/False: The uncharged form of a weak base with a pKa=8.2 would be most abundant at a pH=1.6

A

FALSE- A weak base will dissociate in an acidic solution and the charged form will dominate

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4
Q

True/False: The charged form of a weak acid with a pKa=4.3 would be most abundant at a pH=2.8

A

FALSE- A weak acid will not dissociate in an acidic solution and the uncharged form will dominate

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5
Q

True/False: If drug A is more potent than drug B, then drug B is more efficacious than drug A

A

FALSE- potency is amount of drug req for intended effect, efficacy is ability to produce physiological alteration

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6
Q

True/False: Pareneteral administration of a drug is the most effect route of administration

A

FALSE- Multifactorial considerations

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7
Q

True/False: Pharmocodynamics deals with the effects of a drug on the body

A

TRUE

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8
Q

The liver plays a major role in drug excretion

A

TRUE

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9
Q

Drugs administered IV have 1000% bioavailability

A

TRUE

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10
Q

True/False: Tachycardia can result from the administration of metoprolol because it has β1 affinity

A

FALSE- Reflex tachycardia is β1-mediated so metoprolol blocks the reflex

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11
Q

True/False: Tachycardia can result from the administration of bethanecol because it is a direct-acting muscarinic agonist

A

FALSE- no one cares

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12
Q

True/False: Tachycardia can result from the administration of neostigmine because it is a muscarinic antagonist

A

FALSE- Neostigmine is a muscarinic agonist

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13
Q

True/False: Tachycardia can result from the administration of phenylephrine because it increases SVR

A

FALSE- idk why

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14
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will stimulate E secretion from the adrenal medulla

A

TRUE

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15
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause diarrhea by directly stimulating β2 receptors

A

FALSE

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16
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will decrease SVR by directly stimulating α1 receptors

A

FALSE- α1 receptors are not nicotinic receptors

17
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause spastic skeletal muscle paralysis

A

FALSE- nicotinic(muscle) stimulation will cause twitching

18
Q

True/False: Epinephrine is a positive chronotrope

A

TRUE

19
Q

True/False: Epinephrine decreases digestive system activity due to its β2 effect

A

TRUE

20
Q

True/False: Epinephrine is a positive inotrope

A

TRUE

21
Q

True/False: Epinephrine is a vasoconstrictor due to its α1 effect

A

TRUE

22
Q

True/False: Epinephrine is a vasodilator due to its β2 effect

A

TRUE

23
Q

True/False: Epinephrine is a bronchodilator due to its β2 effect

A

TRUE

24
Q

True/False: Atropine relaxes skeletal muscle because it is a cholinergic receptor antagonist

A

FALSE- ?

25
Q

True/False: Atropine is a positive chronotrope because it is an antimuscarinic drug

A

TRUE

26
Q

True/False: Atropine decreases bronchial mucous secretion by blocking Nn receptors

A

FALSE- ?

27
Q

True/False: Atropine is a bronchodilator

A

TRUE

28
Q

True/False: Labetalol causes reflex tachycardia

A

FALSE-Reflex tachycardia is β1-mediated so labetalol blocks the reflex

29
Q

True/False: Labetalol is a vasodilator

A

TRUE

30
Q

True/False: Labetalol can cause orthostatic hypotension by blocking adrenergic receptors

A

TRUE

31
Q

True/False: Labetalol lowers BP by reducing CO

A

TRUE

32
Q

True/False: Metoprolol lowers BP by reducing SVR

A

FALSE-

33
Q

True/False: Metoprolol directly reduces CO

A

TRUE

34
Q

True/False: Metoprolol targets the same receptors as dobutamine

A

TRUE

35
Q

True/False: Metoprolol causes reflex bradycardia

A

FALSE-Reflex tachycardia is β1-mediated so metoprolol blocks the reflex

36
Q

True/False: Phenylephrine causes reflex bradycardia because it reduces BP

A

FALSE-Phenylephrine stimulates α1 receptors- vasoconstriction would cause reflex tachycardia

37
Q

True/False: Phenylephrine targets a receptor targeted by NE

A

TRUE

38
Q

True/False: Phenylephrine directly increases myocardial contractility

A

FALSE-Phenylephrine stimulates α1 receptors causing vasoconstriction

39
Q

True/False: Phenylephrine is an effective decongestant

A

TRUE

Biology4351 (16 decks)

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