drugs for whatever Flashcards
(D/(*/~))(nmab)(+/-): Neostigmine
Indirect (~reuptake) cholinomimetic
(D/(*/~))(nmab)(+/-): Nicotine
Direct nicotinic receptor agonist
(D/(*/~))(nmab)(+/-): Bethanechol
Direct muscarinic receptor agonist
(D/(*/~))(nmab)(+/-): Methamphetamine
Indirect (*release) sympathomimetic
(D/(*/~))(nmab)(+/-): MAOI
Indirect (~reuptake) sympathomimetic
(D/(*/~))(nmab)(+/-): TCA
Indirect (~reuptake) sympathomimetic
(D/(*/~))(nmab)(+/-): Cocaine
Indirect (~reuptake) sympathomimetic
(D/(*/~))(nmab)(+/-): Epinephrine
α1, α2, β1, β2 direct adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): NE/Levophed
α1, α2, β1 direct adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): Phenylephrine
α1 direct adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): Clonidine
α2 adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): Dobutamine
β1 adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): Albuterol/Terbutaline
β2 adrenergic receptor agonist
(D/(*/~))(nmab)(+/-): “ganglionic blockers”
Nn cholinergic receptor antagonist
(D/(*/~))(nmab)(+/-): Atracurium
Nm cholinergic receptor antagonist
(D/(*/~))(nmab)(+/-): Vecuronium
Nm cholinergic receptor antagonist
(D/(*/~))(nmab)(+/-): Succinylcholine
Nm cholinergic antagonist
(D/(*/~))(nmab)(+/-): Atropine
Muscarinic receptor antagonist
(D/(*/~))(nmab)(+/-): Glycopyrrolate
Muscarinic receptor antagonist
(D/(*/~))(nmab)(+/-): Ipratropium
Muscarinic receptor antagonist
(D/(*/~))(nmab)(+/-): Tiotropium
Muscarinic receptor antagonist
(D/(*/~))(nmab)(+/-): Propanolol
Beta blocker
(D/(*/~))(nmab)(+/-): Prazosin
α1 blocker
(D/(*/~))(nmab)(+/-): Labetalol
α1, β1, β2 blocker
(D/(*/~))(nmab)(+/-): Metoprolol
β1 blocker
(D/(*/~))(nmab)(+/-): Atenolol
β1 blocker
Name me a non-selective beta blocker
Propanolol
Give me some weirdly pseudo opposite drugs (an agonist and an antagonist)
NE stimulates α1, α2, β1
Labetalol blocks α1, β1, β2
What receptor mediates reflexive tachycardia?
β1 receptors
Name me some β1 blockers
Metoprolol
Atenolol
(Propanolol)
(Labetalol)
Name me some α1 blockers
Prazosin
Labetalol
Give me α1, α2, β1, β2 agonists in order
Phenylephrine
Clonidine
Dobutamine
Albuterol/Terbutaline
Give me our three cholinergic agonists
Neostigmine (~ cholinomimetic)
Nicotine (D m cholinomimetic)
Bethanechol (D m cholinomimetic)
Give me our three antinicotinics (m)
Atracurium
Vecuronium
Succinylcholine
Give me our four antimuscarinics
Atropine
Glycopyrrolate
Ipratropium
Tiotropium
What are beta blockers never
Beta blockers are never vasodilators
What is atracurium used for?
blocks nm junctions
flaccid paralysis
What is vecuronium used for?
blocks nm junctions
flaccid paralysis
What is succinylcholine used for?
blocks nm junctions
(irreversible, short term) flaccid paralysis
What is atropine used for?
blocks M2 site
increases HR
treat sinus bradycardia
What is glycopyrrolate used for?
blocks M3
reduce glandular activity
reduce bronchial secretions
What is ipratropium used for?
blocks M3
relaxes s.m.
treats COPD
What is tiotropium used for?
blocks M3
relaxes s.m.
treats COPD
What is propanolol used for?
blocks β1, β2
slows HR, constricts s.m.
treats hypertension
What is labetalol used for?
blocks α1, β1, β2
vasodilation, slows HR, constricts s.m.
treats emergency hypertension
What is prazosin used for?
blocks α1
vasodilation
reduces blood pressure
What is metoprolol used for?
blocks β1
slows HR
treats congestive heart failure
What is atenolol used for?
blocks β1
slows HR
treats congestive heart failure
What is neostigmine used for?
reduces ACh reuptake
reverses paralyzing blockers
What is nicotine used for?
stimulates N receptors
energy boost and P/SNS enhancement
What is bethanechol used for?
stimulates M3 cells
treats urinary problems
What is meth used for?
increases NE release
stimulant
What is cocaine used for?
reduce NE reuptake
stimulant
What is epinephrine used for?
stimulates α1, α2, β1, β2
vasoconstriction, reduces SNS, increases HR, relaxes s.m.
What is norepinephrine used for?
stimulates α1, α2, β1
vasoconstriction, reduces SNS, increases HR
What is levophed used for?
stimulates α1, α2, β1
vasoconstriction, reduces SNS, increases HR
What is phenylephrine used for?
stimulates α1
vasoconstriction
What is clonidine used for?
stimulates α2
reduces SNS
What is dobutamine used for?
stimulates β1
increases HR
treats heart failure
What is albuterol used for?
stimulates β2
relaxes s.m.
tocolytic
What is terbutaline used for?
stimulates β2
relaxes s.m.
bronchodilator
Complete the equation: BP = ?
BP = CO x SVR
Complete the equation: CO = ?
CO = HR x SV
Complete the equation: SV = ?
Myocardial contractility x
When does baroreceptor reflex occur?
Change in BP
What group of drugs prevents the baroreceptor reflex?
Beta blockers
What two conditions can the baroreceptor reflex cause?
Reflexive tachycardia
Reflexive bradycardia
Specifically what receptor mediates the baroreceptor reflex?
β1 receptors
Eight ways to treat hypertension!
Diuretics Beta blockers ACE Inhibitors/ARBs Ca++ channel blockers Central sympatholytics α1 blockers Direct arterial dilators
Name four classes of diuretics
Loop diuretics- Furosemide
DCT diuretics- HCTZ
K+ sparing- Ameloride, Triamterene, Spironolactone
Osmotics- Mannitol
Name your drugs that affect angiotensin (at all)
Captopril
Lisinopril
LoSARtin
Name your Ca++ channel blockers
Nifedipine
Amlodipine
Diltiazem
Verapamil
Name some standalone drugs for hypertensive treatment (drugs who’s class we know like one of)
Central sympatholytics- clonidine
α1 blockers- prazosin
DAD- hydralazine
Drugs to treat angina pectoris?
Nitrates
Beta blockers
Ca++ channel blockers
Name your nitrates
Nitroglycerin
Isosorbide dintrate
Drugs to treat hypertensive emergency
Labetalol
Nitroprusside Na
Drugs to treat systolic heart failure
Dobutamine
Digoxin
Generally how to treat systolic heart failure?
Improve contractility
Reduce workload
Generally how to treat diastolic heart failure?
Increase filling time
Reduce workload
How to reduce workload?
Reduce SNS activity
Reduce fluid retention
Drugs to reduce workload
Diuretics
ACE Inhibitors, ARBs
Beta blockers
Nitroprusside Na
Drugs to increase filling time
Beta blockers
Ca ++ Channel blockers
ACE Inhibitors/ARBs
Diuretics
Heart drugs that affect just preload?
Diuretics
Heart drugs that affect preload and afterload?
ACE Inhibitors, ARBs
Nitroprusside Na
Heart drugs that affect just afterload?
NONE HAHAHAHAHAHAHAHAHAHAHAH
Heart drugs that affect neither preload nor afterload?
Beta blockers
