Basics Flashcards
α1 receptors are located…
on vascular smooth muscle
α2 receptors are located…
on presynaptic adrenergic nerve terminals
β1 receptors are located…
in the heart
β2 receptors are located…
on all smooth muscle cells
M1 receptors are located…
on gastric parietal cells
M2 receptors are located…
in the heart
M3 receptors are located…
on smooth muscle cells (except vascular s.m.) & glands
Nn receptors are located…
in autonomic ganglia & adrenal medulla
Nm receptors are located…
at NMJ of somatic nervous system
Stimulation of α1 receptors results in…
vasoconstriction
Stimulation of α2 receptors results in…
reduced NE output
Stimulation of β1 receptors results in…
increased heart rate
increased myocardial contractility
Stimulation of β2 receptors results in…
contraction of all smooth muscle
Stimulation of M1 receptors results in…
increased HCl secretion
Stimulation of M2 receptors results in…
increased heart rate
Stimulation of M3 receptors results in…
contraction of s.m. (-vasc) & gland secretion
Stimulation of Nn receptors results in…
slight energy boost
Stimulation of Nm receptors results in…
twitching???
BLOCKING α1 receptors results in…
vasodilation
BLOCKING α2 receptors results in…
increased NE output
BLOCKING β1 receptors results in…
reduced heart rate
increased myocardial contractility
BLOCKING β2 receptors results in…
relaxation of all smooth muscles
BLOCKING of M1 receptors results in…
reduced HCl secretion
BLOCKING of M2 receptors results in…
reduced heart rate
BLOCKING of M3 receptors results in…
relaxation of s.m. (-vasc) & gland inhibition
BLOCKING of Nn receptors results in…
shut down ANS
BLOCKING of Nm receptors results in…
flaccid paralysis
(side) effects of taking an anticholinergics
Dry mouth Blurred vision (reflexive) Tachycardia Constipation, Urinary retention Bronchodilation (only)
(side) effects of taking a central sympatholytics
shuts down ANS, flaccid paralysis
