Sulfo, Quino, Trime Flashcards

0
Q

Among quinolones what causes torsades, tendinitis and hypohyperglycemia

A

Gatifloxin

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1
Q

Among all quinolones which is the most toxic

A

Gatifloxin

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2
Q

Give a first gen quino

A

Nalidixic acid

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3
Q

This group of drug is very effective against UTI even MDR bacteria such as aeruginosa

A

Quinolones

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4
Q

All quinolones are effective against MDR except?

A

Moxiflocin

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5
Q

Most common SE of quinolone

A

NVD

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6
Q

Why must quinolones given in the AM

A

Causes insomnia

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7
Q

Among all quinolones what is/are effective against anthrax and meningoccocemia

A

Ciprofloxacin

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8
Q

What can be given for chlamydia

A

Ciprofloxqcin and levofloxacin

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9
Q

Ciprofloxacin and levofloxacin can be given for?

A

Chlamydia

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10
Q

Whaqr quinolones that can be used for MAC

A

Levo, cipro, moxi

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11
Q

Among all quinolones, which annot be used for UTI because it has hepatic route

A

Moxifloxacin and Travo

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12
Q

What isomer of ofloxacin is highly active

A

L-isomer

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13
Q

What can be used in px with renal failure but must use quinolones for respi tract infxn

A

Moxi and Travo – hepatic

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14
Q

Nitromizadole antiprotozoal drug

A

Metronidazole

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15
Q

Has a metallic taste

A

Metronidazole

16
Q

Needs to be reduced by ferredoxin to be activated

A

Metronidazole

17
Q

Inhibits topoisomerase ii and iv

A

DNA gyrase inhibitors

18
Q

Do cross resistance exist among quinolones

A

Yes because they act on the same enzyme

19
Q

Mode killing of fluoroquinolones

A

Concentration dependent

20
Q

What do u call the activity created with combining trimep and sulfo

A

Sequential syngergistix blockade

21
Q

When taking sulfonamide, what drugs must be taken extra care of

A

Phenytoin, warfarin, sulfonyureas

22
Q

Inhibits tetrahydrofolate synthesis by inhibiting dihydrofolate enzyme

A

Trimethoprim

23
Q

Which is more lipid soluble, sulfa or trime?

24
Drug used for malaria?
Sulfadoxine plus pyrimethamone
25
Drug for acute toxoplasmosis
Sufadiazine plus pyrimethamine plus folinic acid
26
Sulfonamides
Bactericidal
27
Trimetophrim
Bacteriostatic
28
Sulfo plus trime
Cidal
29
Metronidazeol
Cidal
30
Quinolones
Cidal
31
Drugs for H. Pylori
MCAT METRO, CLARITHRO, TETRA, METRO
32
Respiratory fluoroquinolones
Gmgl Gati, moxi, gemi, levo
33
True or false, when combining sulfo and tri, half lives must be the same
True