Sulfo, Quino, Trime Flashcards
Among quinolones what causes torsades, tendinitis and hypohyperglycemia
Gatifloxin
Among all quinolones which is the most toxic
Gatifloxin
Give a first gen quino
Nalidixic acid
This group of drug is very effective against UTI even MDR bacteria such as aeruginosa
Quinolones
All quinolones are effective against MDR except?
Moxiflocin
Most common SE of quinolone
NVD
Why must quinolones given in the AM
Causes insomnia
Among all quinolones what is/are effective against anthrax and meningoccocemia
Ciprofloxacin
What can be given for chlamydia
Ciprofloxqcin and levofloxacin
Ciprofloxacin and levofloxacin can be given for?
Chlamydia
Whaqr quinolones that can be used for MAC
Levo, cipro, moxi
Among all quinolones, which annot be used for UTI because it has hepatic route
Moxifloxacin and Travo
What isomer of ofloxacin is highly active
L-isomer
What can be used in px with renal failure but must use quinolones for respi tract infxn
Moxi and Travo – hepatic
Nitromizadole antiprotozoal drug
Metronidazole
Has a metallic taste
Metronidazole
Needs to be reduced by ferredoxin to be activated
Metronidazole
Inhibits topoisomerase ii and iv
DNA gyrase inhibitors
Do cross resistance exist among quinolones
Yes because they act on the same enzyme
Mode killing of fluoroquinolones
Concentration dependent
What do u call the activity created with combining trimep and sulfo
Sequential syngergistix blockade
When taking sulfonamide, what drugs must be taken extra care of
Phenytoin, warfarin, sulfonyureas
Inhibits tetrahydrofolate synthesis by inhibiting dihydrofolate enzyme
Trimethoprim
Which is more lipid soluble, sulfa or trime?
Trume