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PHARMA 3.0 > Sulfo, Quino, Trime > Flashcards

Sulfo, Quino, Trime Flashcards

0
Q

Among quinolones what causes torsades, tendinitis and hypohyperglycemia

A

Gatifloxin

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1
Q

Among all quinolones which is the most toxic

A

Gatifloxin

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2
Q

Give a first gen quino

A

Nalidixic acid

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3
Q

This group of drug is very effective against UTI even MDR bacteria such as aeruginosa

A

Quinolones

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4
Q

All quinolones are effective against MDR except?

A

Moxiflocin

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5
Q

Most common SE of quinolone

A

NVD

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6
Q

Why must quinolones given in the AM

A

Causes insomnia

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7
Q

Among all quinolones what is/are effective against anthrax and meningoccocemia

A

Ciprofloxacin

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8
Q

What can be given for chlamydia

A

Ciprofloxqcin and levofloxacin

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9
Q

Ciprofloxacin and levofloxacin can be given for?

A

Chlamydia

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10
Q

Whaqr quinolones that can be used for MAC

A

Levo, cipro, moxi

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11
Q

Among all quinolones, which annot be used for UTI because it has hepatic route

A

Moxifloxacin and Travo

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12
Q

What isomer of ofloxacin is highly active

A

L-isomer

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13
Q

What can be used in px with renal failure but must use quinolones for respi tract infxn

A

Moxi and Travo – hepatic

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14
Q

Nitromizadole antiprotozoal drug

A

Metronidazole

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15
Q

Has a metallic taste

A

Metronidazole

16
Q

Needs to be reduced by ferredoxin to be activated

A

Metronidazole

17
Q

Inhibits topoisomerase ii and iv

A

DNA gyrase inhibitors

18
Q

Do cross resistance exist among quinolones

A

Yes because they act on the same enzyme

19
Q

Mode killing of fluoroquinolones

A

Concentration dependent

20
Q

What do u call the activity created with combining trimep and sulfo

A

Sequential syngergistix blockade

21
Q

When taking sulfonamide, what drugs must be taken extra care of

A

Phenytoin, warfarin, sulfonyureas

22
Q

Inhibits tetrahydrofolate synthesis by inhibiting dihydrofolate enzyme

A

Trimethoprim

23
Q

Which is more lipid soluble, sulfa or trime?

A

Trume

24
Q

Drug used for malaria?

A

Sulfadoxine plus pyrimethamone

25
Q

Drug for acute toxoplasmosis

A

Sufadiazine plus pyrimethamine plus folinic acid

26
Q

Sulfonamides

A

Bactericidal

27
Q

Trimetophrim

A

Bacteriostatic

28
Q

Sulfo plus trime

A

Cidal

29
Q

Metronidazeol

A

Cidal

30
Q

Quinolones

A

Cidal

31
Q

Drugs for H. Pylori

A

MCAT METRO, CLARITHRO, TETRA, METRO

32
Q

Respiratory fluoroquinolones

A

Gmgl

Gati, moxi, gemi, levo

33
Q

True or false, when combining sulfo and tri, half lives must be the same

A

True

PHARMA 3.0 (7 decks)

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