Subcutaneous Mycoses Flashcards

1
Q

Subcutaneous Mycoses

Habitat

A

Soil, plants, organic debris, etc

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2
Q

Subcutaneous Mycoses

Transmission

A

Contaminated thorns

Implantation into traumatized skin (spores)

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3
Q

Subcutaneous Mycoses

Lesions

A

Abscesses
Nonhealing ulcers
Draining sinus tracts

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4
Q

Sporothrix schenckii

Characteristics

A

Dimorphic fungus

Causes Sporotichosis

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5
Q

Sporothrix schenckii

Habitat

A

Soil, vegetation, and wood

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6
Q

Sporothrix schenckii

Host species

A

Humans, horses, dogs, and cats

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7
Q

Sporothrix schenckii

Pathogenesis

A

Infection of the extremities via trauma
Ulcerating nodules along the superficial lymphatic vessels
Lymphangitis—thickened and cordlike vessels
(skin and lymphatic vessels)

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8
Q

Equine SPorothricosis

A

Hard cutaneous nodules along the lymphatic, ulcerating and draining (cigar shaped yeasts cells)

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9
Q

Feline Sporothricosis

A

Mainly male cats, draining puncture wounds, head or tail base (cigar shaped yeasts cells)

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10
Q

Pythium insidiosum

A

Causes: Mycotic Swamp Cancer, Florida Horse Leeches
- Aquatic plant fungus
Host: humans, horses, dogs and cattle

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11
Q

Mycotic Swamp Cancer

Pathogenesis

A

Invasion of traumatized skin or intestinal mucosa by motile zoospores
Germination of zoospores to form aseptate hyphae
Pyogranulomatous lesions with fistulous tracts discharging purulent exudate

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12
Q

Myotic Swamp Cancer

Equine pythiosis

A

mostly cutaneous lesions
Ex: Draining mass on the rear leg of a horse
Ex: Granular, irregularly-shaped yellow “kunkers” w/n the mass

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13
Q

Myotic Swamp Cancer

Canine pythiosis

A

Mostly alimentary tract lesions

EX; Granulomatus Gastritis

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14
Q

Myotic Swamp Cancer

Laboratory Diagnosis

A

Lactophenol Cotton Blue Stain

Masses of hyphae

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15
Q

Aspergillus Species

Characteristics

A

aerobic,

Saprophytic moulds with septate hyaline hyphae. Unbranched conidiophores are formed from phialides borne on vesicles

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16
Q

Aspergillus funigatus

Pathogenesis

A

Inhalation or ingestion
Primary lesions occur in the respiratory tract
Possible dissemination via the bloodstream
Lesions: granulomatous lesions [yellowish-gray nodules]

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17
Q

Aspergillosis BIRDS

A

Brooder pneumonia and airsacculitis in Respiratory Tract

18
Q

Aspergillosis Horses

A

Guttural pouch mycosis, keratitis, intestinal aspergillosis

19
Q

Aspergillosis Cattle

A

Muycotic abortion, Mycotic penumonia, Mycotic mastitis

20
Q

Aspergillosis Dogs

A

Otitis externa
Chronic rhinks
Aspergilosis with thrombosis of vessels

21
Q

Aspergillosis

A

Immunocompromised humans with prolonged antibiotics involve the lungs and skin of inhalation of spores can lead to a hypersensitive state

22
Q

Avain Aspergillosis (Brooder Penumonia) Transmission

A

Inhalation

23
Q

Avain Aspergillosis (Brooder Penumonia) Clinical Findings

A

Acute: Gasping, loss of appetite, paralysis or convulsions
Chronic: Emaciation, cyanosis, etc

24
Q

Avain Aspergillosis (Brooder Penumonia) Pathology

A

Yellowish-grean granulomatous plaques

25
Laboratory Diagnosis for Aspergillosis of
Conidophore and Conidiospores
26
Fungal Dimorphism
``` Mold Form (25C to 30C) Yeats or spherule form (35 to 37) ```
27
Blastomyces dermatitidis
Causes: North American Blastomycosis in humans and dogs
28
North American Blastomycosis in humans and dogs | Epidemiology
Found in acid soil enriched with manure and other organic matter Inhalation of aerosolized conidia
29
Blastomycosis | Pathogensis
Primary lesions: Lungs Hematogenous dissemination Eye, skin, liver, CNS, etc Granulomatous lesions
30
Blastomycosis Clinical Findings
Dogs: Fever, weight loss, chronic cough, dyspnea, etc
31
Blastomycosis | Laboratory Diagnosis
FA stain: Fluorecing Budding Yeast Cells
32
Coccidioides immitis
Causes Coccidioidomycosis in dogs, horses and humans [San Joachim Valley Fever]
33
Coccidioidomycosis in dogs, horses and humans [San Joachim Valley Fever] Epidemiology
Arid soils | Inhalation of arthrospores
34
Coccidioidomycosis | Pathogenesis
Lungs: Primary lesions Hematogenous dissemination Lesions: Granulomatous nodules
35
Coccidioidomycosis | Laboratory Diangnosis
Barrel-Shaped Arthrospores | PAS stain, Spherule
36
Histoplasmosis capsulatumm
Causes: Histoplasmosis in humans, dogs and cats
37
Histoplasmosis in humans, dogs and cats | Epidemiology
Found in soils enriched with bat or bird feces | Inhalation of airborne conidia
38
Histoplasmosis | Pathogenesis
Intracellular fungus—replicates in monocytes and macrophages Primary lesions: Lungs Hematogenous spread Infection of intestine, liver, etc
39
Histoplasmosis | Clinical Presentations
Many infected dogs don’t get sick. Some develop mild to severe respiratory and/or gastrointestinal disease, with breathing difficulties, fever, weight loss, vomiting, muscle wasting, coughing and intractable diarrhea
40
Feline Histoplasmosis | Transmission
Enters an animals intestinal tract after being ingested through contaminated soil or bird
41
Feline Histoplasmosis | Clinical Presentations
Increased breathing effort and harsh lung sounds Lameness Eye discharge Diarrhea Fever, up to to 40 degrees Celsius (104.0 degrees Fahrenheit) Pale gums and moist body tissues (mucous membrane)
42
Histoplasmosis | Laboratory Diagnosis
Numerous Yeast Forms of H. capsula-tum in Alveolar Macrophages