Haemobartonella Flashcards
Characteristics of Haemobartonella
Short rods or cocci
Epicellular organisms
Found on cell surfaces of erythrocytes
Mycoplasma haemofelis
Feline Infectious Anemia
Feline Infectious Anemia
Organisms are found on the surfaces of ery-throcytes or free in the plasma
Feline Infectious Anemia
Blood Smear
Rings, cocci, or rods
Feline Infectious Anemia
Transmission
Hematophagous arthropods, eg, fleas
Bite wounds and blood transfusion
Feline Infectious Anemia
Pathogenesis
Fluctuating packed cell volume
Regenerative anemia
Latency
Feline Infectious Anemia
Clinical Finding
Acute: Fever, anorexia, splenomegaly, hemolytic anemia, weight loss, and icterus
Chronic: Anemia, depression and weakness
Feline Infectious Anemia
Diagnosis
Clinical signs
Examination of blood and/or bone marrow smears
Feline Infectious Anemia
Treatment
Blood transfusion?
Doxycycline
Genus Mycoplasma (Eperythrozoon)
Organisms are found on erythrocytes and free in plasma
Coccoid, rings or rod-shaped
Mycoplasma(Eperythrozoon) suis
Icteroanemia in swine
Icteroanemia in swine
Transmission
Mechanical transmission by Hematopinus suis
Iatrogenic transmission
Icteroanemia in swine
Pathogenesis
Removal of infected erythrocytes results in anemia
Lifelong subclinical carrier state
Icteroanemia in swine
Clinical Findings
Fever, anemia, icterus, and general weakness
Icteronanemia
Diagnosis
Organisms in stained blood smear
Presence of lice
Icteronanemia
Serology
Detection of antibodies in serum
Icteronanemia
Treatment
Tetracyclines in feed or water
Anaplasma
The organisms form inclusions in erythrocytes or granulocytes
Demonstration of organisms
Stained blood smears
Anaplasma marginale
Anaplasmosis
Cattle, deer, other ruminants
Transmission
Biological transmission by Boophilus spp., Dermacentor spp., etc
Mechanical stransmission by biting flies, eg, stable flies, mosquitoes, tabanids, etc
Iatrogenic transmission
Transplacental transmission
Anaplasmosis
Pathogenesis
Organisms form microcolonies in RBCs
Removal of infected RBCs results in anemia and icterus
No hemoglobinuria
Anaplasmosis
Clinical Findings
Calves < 6 months of age—resistant to disease but not infection
Anemia, intermittent fever, icterus, abortion, etc
Highly fatal if untreated
Anaplasmosis
Diagnosis
Giemsa-stained blood smears
PCR
Anaplasmosis
Serology
Detects carrier animals
Card agglutination test, ELISA, etc
Anaplasmosis
Vaccination
Vaccine prevents disease but not infection
