Sub gingival Plaque - The pathogens Flashcards
1
Q
What bacteria are involved in Rapidly progressing periodontitis (RPP)?
A
- A. actinomycetemcomitans (found in 90% of sites)
- Eikenella corrodens
- Prevotella intermedia & Campylobacter rectus
2
Q
What can Porphyromonas cause?
A
periodontitis & bone destruction
3
Q
What is the outer membrane of Gram - negatives?
A
- Assymetric membrane
- Lipopolysaccharides (LPS)
- Peptidoglycan
- Lipoteichoic acid (LTA)
- Lipoproteins
bind to receptors on macrophages, B cells & other cells that stimulates release of acute phase cytokines.
4
Q
Where is Prevotella found?
A
Gingival sulcus and periodontal pocket
5
Q
What does Tannerella Forsythia induce?
A
Induces release of bone reabsorbing pro-inflammatory cytokines
Induces chemokines (recruit neutrophils, inflammation, tissue destruction)
6
Q
What can Fusobacterium nucleatum cause?
A
- Diversification of Plaque
- Periodontal Disease
- AUG
- Still Births
- Colorectal Cancer
7
Q
Is Fusobacterium spp. Gram +ve or Gram -ve?
A
Gram -ve spindle shaped bacteria
8
Q
A