Sub gingival Plaque - The pathogens Flashcards

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1
Q

What bacteria are involved in Rapidly progressing periodontitis (RPP)?

A
  • A. actinomycetemcomitans (found in 90% of sites)
  • Eikenella corrodens
  • Prevotella intermedia & Campylobacter rectus
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2
Q

What can Porphyromonas cause?

A

periodontitis & bone destruction

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3
Q

What is the outer membrane of Gram - negatives?

A
  • Assymetric membrane
  • Lipopolysaccharides (LPS)
  • Peptidoglycan
  • Lipoteichoic acid (LTA)
  • Lipoproteins

bind to receptors on macrophages, B cells & other cells that stimulates release of acute phase cytokines.

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4
Q

Where is Prevotella found?

A

Gingival sulcus and periodontal pocket

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5
Q

What does Tannerella Forsythia induce?

A

Induces release of bone reabsorbing pro-inflammatory cytokines

Induces chemokines (recruit neutrophils, inflammation, tissue destruction)

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6
Q

What can Fusobacterium nucleatum cause?

A
  • Diversification of Plaque
  • Periodontal Disease
  • AUG
  • Still Births
  • Colorectal Cancer
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7
Q

Is Fusobacterium spp. Gram +ve or Gram -ve?

A

Gram -ve spindle shaped bacteria

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8
Q
A
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