Periodontitis: Experimental Evidence

Question 1

What doe Epidemiological studies in Plaque & periodontitis show?

Answer 1

• Clear epidemiological evidence difficult to obtain
• Indicies
• Site variation
• Individual variation

Question 2

What is a microbiological study linking plaque and perio disease?

Answer 2

Moore & Moore 1994

• different sites & levels of periodontal disease
• 17,000 isolates
• 600 sites
• conventional techniques
  
  • A.naeslundii & F.nucleatum in health and disease

Question 3

What is another microbiology study linking plaque and perio disease?

Answer 3

Socransky 1998

• 185 subjects
  
  • different levels of perio disease
• 13,261 subgingival plaque samples
• Assayed for presence of 40 species of bactieria
• DNA-DNA hybridisation

Question 4

What are the 5 clusters?

Answer 4

• Red - deep perio pockets
• Orange - deep perio pockets
• Yellow
• Purple
• Green

Question 5

What is Curtis et. al. proposed 3 ‘Cs’?

Answer 5

• Community change
• Microbial Complexes
• Commensal involvement