Study unit 2.1 Nervous System Flashcards
Neurons
Individual cells that receive, integrate and transmit information. They are the basic links.
Dendrite
Feeler-like branch that receives the information.
Soma (cell body)
Cell nucleus or the chemical machinery where information flows through.
Axon
Long, thin fibre that transmits signals to other neurons, muscles or glands.
Myelin
Insulating material that encases the axon and speeds up signal transmission and stabilizes axon structures and patterns of connection.
Terminal buttons
Small knobs that secrete neurotransmitters.
Synapses
Points where neurons interconnect and information is transmitted from one neuron to another.
Action potential
Brief shift in electrical charge, traveling along axon.
Inside and outside the neuron there are fluids in which there is electrically charged atoms and ions. The + sodium and potassium and the - chloride flow back and forth across the cell membrane. When stimulated the cell membrane opens and lets + sodium come in resulting in it being less negative and it gradually becomes positive within the cell membrane.
Resting potential
Stable negative charge when cell is inactive
Glia
Cells found throughout the nervous system that provides various types of support for neurons. They supply nourishment to neurons, help remove waste from neurons and provide insulation around many axons. Heroes of NS. Some types can detect neural impulses and send signals to other glia cells.
Absolute refractory
Minimum length of time after an action potential before another action potential can begin. “Downtime”
Synoptic cleft
The microscopic gap between the terminal button, neuron and cell membrane of another cell membrane. It is where the signals cross.
Postsynaptic potential (PSP)
Neurotransmitter and receptor molecule combine. A voltage change occurs at the receptor site on the postsynaptic cell membrane. Don’t follow all or none law, is graded (vary in size) and increases or decreases the probability of a neural impulse in the receiving cell in proportion to the amount of voltage change.
Excitory message (PSP)
+ voltage shift that increases the likelihood of AP fire
Inhibatory message (PSP)
- voltage shift that decreases the likelihood of AP fire
Reuptake
Neurotransmitters are sponged up from the synaptic cleft by the presynaptic membrane. Recycled.
Synaptic pruning
The elimination of old synapses, the nervous system forms more synapses than needed and gradually eliminates the less active. It is a key process in neural network formation and is crucial to communication in the nervous system.
Acetylcholine (ACh)
Released by motor neurons controlling skeletal muscles. Contributes to the regulation of attention, arousal, and memory. Some receptors are stimulated by nicotine. The disorder associated is Alzheimer’s.
Dopamine (DA) - Monoamine
Control of voluntary movement. Activity at synapses is activated by cocaine and amphetamines. Dopamine circuits in mediual forebrain characterised as the “reward pathway’. The disorders associated is Parkinsons, Schizophrenic and addictive.
Norepinephrine (NE) - Monoamine
Modulation of mood and arousal. Activity at synapses is activated by cocaine and amphetamines. Depressive disorders are associated.
Serotonin - Monoamine
The regulation of sleep and wakefulness , eating and aggression. Serotonin circuits affected by prozac and similar antidepressant drugs. The disorders associated are depressive, obsessive-compulsive and eating.
GABA (Gamma-aminobutyric acid)
An inhibatory transmitter. Regulation of anxiety and sleep/arousal. Valium and similar antianxiety drugs. Anxiety disorders are associated.